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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Prmt6
Full Name:
Protein arginine N-methyltransferase 6
Alias:
EC 2.1.1.-; Flj10559; Hrmt1l6; Protein arginine methyltransferase 6
Type:
Enzyme -Methyltransferase
Mass (Da):
41938
Number AA:
375
UniProt ID:
Q96LA8
International Prot ID:
IPI00102128
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042393
GO:0070612
GO:0070611
PhosphoSite+
KinaseNET
Biological Process:
GO:0006284
GO:0034970
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
K
K
R
K
L
E
S
G
G
G
G
E
G
G
Site 2
T21
G
G
E
G
G
E
G
T
E
E
E
D
G
A
E
Site 3
T39
A
L
E
R
P
R
R
T
K
R
E
R
D
Q
L
Site 4
Y47
K
R
E
R
D
Q
L
Y
Y
E
C
Y
S
D
V
Site 5
Y48
R
E
R
D
Q
L
Y
Y
E
C
Y
S
D
V
S
Site 6
Y51
D
Q
L
Y
Y
E
C
Y
S
D
V
S
V
H
E
Site 7
T67
M
I
A
D
R
V
R
T
D
A
Y
R
L
G
I
Site 8
Y70
D
R
V
R
T
D
A
Y
R
L
G
I
L
R
N
Site 9
S169
L
H
E
S
M
L
S
S
V
L
H
A
R
T
K
Site 10
S197
E
L
F
I
A
P
I
S
D
Q
M
L
E
W
R
Site 11
Y215
W
S
Q
V
K
Q
H
Y
G
V
D
M
S
C
L
Site 12
S259
R
F
A
Q
L
E
L
S
R
A
G
L
E
Q
E
Site 13
Y280
G
R
F
R
C
S
C
Y
G
S
A
P
M
H
G
Site 14
S308
S
E
K
P
L
V
L
S
T
S
P
F
H
P
A
Site 15
S310
K
P
L
V
L
S
T
S
P
F
H
P
A
T
H
Site 16
T316
T
S
P
F
H
P
A
T
H
W
K
Q
A
L
L
Site 17
Y324
H
W
K
Q
A
L
L
Y
L
N
E
P
V
Q
V
Site 18
T335
P
V
Q
V
E
Q
D
T
D
V
S
G
E
I
T
Site 19
S338
V
E
Q
D
T
D
V
S
G
E
I
T
L
L
P
Site 20
T342
T
D
V
S
G
E
I
T
L
L
P
S
R
D
N
Site 21
Y359
R
L
R
V
L
L
R
Y
K
V
G
D
Q
E
E
Site 22
T368
V
G
D
Q
E
E
K
T
K
D
F
A
M
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation