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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C20orf23
Full Name:
Kinesin-like protein KIF16B
Alias:
Sorting nexin-23
Type:
Mass (Da):
151993
Number AA:
1317
UniProt ID:
Q96L93
International Prot ID:
IPI00452247
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0005875
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003774
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006996
GO:0007010
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
F
I
I
Q
M
E
K
S
K
T
T
I
T
N
L
Site 2
T33
I
Q
M
E
K
S
K
T
T
I
T
N
L
K
I
Site 3
T34
Q
M
E
K
S
K
T
T
I
T
N
L
K
I
P
Site 4
T36
E
K
S
K
T
T
I
T
N
L
K
I
P
E
G
Site 5
T45
L
K
I
P
E
G
G
T
G
D
S
G
R
E
R
Site 6
S48
P
E
G
G
T
G
D
S
G
R
E
R
T
K
T
Site 7
T53
G
D
S
G
R
E
R
T
K
T
F
T
Y
D
F
Site 8
T55
S
G
R
E
R
T
K
T
F
T
Y
D
F
S
F
Site 9
T57
R
E
R
T
K
T
F
T
Y
D
F
S
F
Y
S
Site 10
Y58
E
R
T
K
T
F
T
Y
D
F
S
F
Y
S
A
Site 11
S61
K
T
F
T
Y
D
F
S
F
Y
S
A
D
T
K
Site 12
T67
F
S
F
Y
S
A
D
T
K
S
P
D
Y
V
S
Site 13
S69
F
Y
S
A
D
T
K
S
P
D
Y
V
S
Q
E
Site 14
Y72
A
D
T
K
S
P
D
Y
V
S
Q
E
M
V
F
Site 15
S74
T
K
S
P
D
Y
V
S
Q
E
M
V
F
K
T
Site 16
T81
S
Q
E
M
V
F
K
T
L
G
T
D
V
V
K
Site 17
S89
L
G
T
D
V
V
K
S
A
F
E
G
Y
N
A
Site 18
Y101
Y
N
A
C
V
F
A
Y
G
Q
T
G
S
G
K
Site 19
S109
G
Q
T
G
S
G
K
S
Y
T
M
M
G
N
S
Site 20
Y110
Q
T
G
S
G
K
S
Y
T
M
M
G
N
S
G
Site 21
T111
T
G
S
G
K
S
Y
T
M
M
G
N
S
G
D
Site 22
S116
S
Y
T
M
M
G
N
S
G
D
S
G
L
I
P
Site 23
S131
R
I
C
E
G
L
F
S
R
I
N
E
T
T
R
Site 24
T137
F
S
R
I
N
E
T
T
R
W
D
E
A
S
F
Site 25
S143
T
T
R
W
D
E
A
S
F
R
T
E
V
S
Y
Site 26
Y150
S
F
R
T
E
V
S
Y
L
E
I
Y
N
E
R
Site 27
Y154
E
V
S
Y
L
E
I
Y
N
E
R
V
R
D
L
Site 28
S166
R
D
L
L
R
R
K
S
S
K
T
F
N
L
R
Site 29
S167
D
L
L
R
R
K
S
S
K
T
F
N
L
R
V
Site 30
T169
L
R
R
K
S
S
K
T
F
N
L
R
V
R
E
Site 31
Y183
E
H
P
K
E
G
P
Y
V
E
D
L
S
K
H
Site 32
S188
G
P
Y
V
E
D
L
S
K
H
L
V
Q
N
Y
Site 33
Y195
S
K
H
L
V
Q
N
Y
G
D
V
E
E
L
M
Site 34
T211
A
G
N
I
N
R
T
T
A
A
T
G
M
N
D
Site 35
T214
I
N
R
T
T
A
A
T
G
M
N
D
V
S
S
Site 36
S220
A
T
G
M
N
D
V
S
S
R
S
H
A
I
F
Site 37
S221
T
G
M
N
D
V
S
S
R
S
H
A
I
F
T
Site 38
S223
M
N
D
V
S
S
R
S
H
A
I
F
T
I
K
Site 39
S238
F
T
Q
A
K
F
D
S
E
M
P
C
E
T
V
Site 40
T244
D
S
E
M
P
C
E
T
V
S
K
I
H
L
V
Site 41
S256
H
L
V
D
L
A
G
S
E
R
A
D
A
T
G
Site 42
T262
G
S
E
R
A
D
A
T
G
A
T
G
V
R
L
Site 43
S278
E
G
G
N
I
N
K
S
L
V
T
L
G
N
V
Site 44
S293
I
S
A
L
A
D
L
S
Q
D
A
A
N
T
L
Site 45
T299
L
S
Q
D
A
A
N
T
L
A
K
K
K
Q
V
Site 46
T316
P
Y
R
D
S
V
L
T
W
L
L
K
D
S
L
Site 47
S322
L
T
W
L
L
K
D
S
L
G
G
N
S
K
T
Site 48
Y342
I
S
P
A
D
V
N
Y
G
E
T
L
S
T
L
Site 49
S347
V
N
Y
G
E
T
L
S
T
L
R
Y
A
N
R
Site 50
T348
N
Y
G
E
T
L
S
T
L
R
Y
A
N
R
A
Site 51
Y351
E
T
L
S
T
L
R
Y
A
N
R
A
K
N
I
Site 52
T385
A
E
I
A
R
L
K
T
L
L
A
Q
G
N
Q
Site 53
S403
L
D
S
P
T
A
L
S
M
E
E
K
L
Q
Q
Site 54
T419
E
A
R
V
Q
E
L
T
K
E
W
T
N
K
W
Site 55
Y479
H
L
K
E
G
Q
T
Y
V
G
R
D
D
A
S
Site 56
S486
Y
V
G
R
D
D
A
S
T
E
Q
D
I
V
L
Site 57
T487
V
G
R
D
D
A
S
T
E
Q
D
I
V
L
H
Site 58
S566
K
L
R
E
K
R
K
S
G
L
L
S
S
F
S
Site 59
S570
K
R
K
S
G
L
L
S
S
F
S
L
S
M
T
Site 60
S571
R
K
S
G
L
L
S
S
F
S
L
S
M
T
D
Site 61
T577
S
S
F
S
L
S
M
T
D
L
S
K
S
R
E
Site 62
S580
S
L
S
M
T
D
L
S
K
S
R
E
N
L
S
Site 63
S582
S
M
T
D
L
S
K
S
R
E
N
L
S
A
V
Site 64
S587
S
K
S
R
E
N
L
S
A
V
M
L
Y
N
P
Site 65
S611
E
E
L
E
K
L
E
S
K
R
K
L
I
E
E
Site 66
S625
E
M
E
E
K
Q
K
S
D
K
A
E
L
E
R
Site 67
T639
R
M
Q
Q
E
V
E
T
Q
R
K
E
T
E
I
Site 68
T644
V
E
T
Q
R
K
E
T
E
I
V
Q
L
Q
I
Site 69
S657
Q
I
R
K
Q
E
E
S
L
K
R
R
S
F
H
Site 70
S662
E
E
S
L
K
R
R
S
F
H
I
E
N
K
L
Site 71
T701
K
K
R
Q
E
E
E
T
F
L
R
V
Q
E
E
Site 72
Y741
Q
K
E
K
D
E
Q
Y
A
K
L
E
L
E
K
Site 73
S800
D
L
E
G
I
R
E
S
L
L
R
V
K
E
A
Site 74
S881
L
L
E
K
H
D
E
S
V
T
D
V
T
E
V
Site 75
T886
D
E
S
V
T
D
V
T
E
V
P
Q
D
F
E
Site 76
Y904
P
V
E
Y
R
L
Q
Y
K
E
R
Q
L
Q
Y
Site 77
S937
I
L
D
R
G
P
L
S
L
D
N
T
L
Y
Q
Site 78
T941
G
P
L
S
L
D
N
T
L
Y
Q
V
E
K
E
Site 79
Y943
L
S
L
D
N
T
L
Y
Q
V
E
K
E
M
E
Site 80
Y959
K
E
E
Q
L
A
Q
Y
Q
A
N
A
N
Q
L
Site 81
T972
Q
L
Q
K
L
Q
A
T
F
E
F
T
A
N
I
Site 82
S996
K
E
K
E
I
L
E
S
R
E
K
Q
Q
R
E
Site 83
S1017
A
R
L
E
R
R
H
S
A
L
Q
R
H
S
T
Site 84
S1023
H
S
A
L
Q
R
H
S
T
L
G
M
E
I
E
Site 85
T1024
S
A
L
Q
R
H
S
T
L
G
M
E
I
E
E
Site 86
S1038
E
Q
R
Q
K
L
A
S
L
N
S
G
S
R
E
Site 87
S1041
Q
K
L
A
S
L
N
S
G
S
R
E
Q
S
G
Site 88
S1043
L
A
S
L
N
S
G
S
R
E
Q
S
G
L
Q
Site 89
S1047
N
S
G
S
R
E
Q
S
G
L
Q
A
S
L
E
Site 90
S1052
E
Q
S
G
L
Q
A
S
L
E
A
E
Q
E
A
Site 91
Y1069
K
D
Q
E
R
L
E
Y
E
I
Q
Q
L
K
Q
Site 92
Y1079
Q
Q
L
K
Q
K
I
Y
E
V
D
G
V
Q
K
Site 93
S1100
E
G
K
V
A
S
S
S
L
P
V
S
A
E
K
Site 94
S1104
A
S
S
S
L
P
V
S
A
E
K
S
H
L
V
Site 95
S1138
Q
D
L
H
R
V
I
S
E
G
C
S
T
S
A
Site 96
S1142
R
V
I
S
E
G
C
S
T
S
A
D
T
M
K
Site 97
T1143
V
I
S
E
G
C
S
T
S
A
D
T
M
K
D
Site 98
Y1165
T
I
Q
R
K
L
K
Y
E
R
M
V
S
R
S
Site 99
S1170
L
K
Y
E
R
M
V
S
R
S
L
G
A
N
P
Site 100
S1172
Y
E
R
M
V
S
R
S
L
G
A
N
P
D
D
Site 101
T1214
K
I
T
V
L
D
E
T
W
T
V
F
R
R
Y
Site 102
T1216
T
V
L
D
E
T
W
T
V
F
R
R
Y
S
R
Site 103
T1230
R
F
R
E
M
H
K
T
L
K
L
K
Y
A
E
Site 104
S1262
R
V
I
A
E
R
R
S
H
L
E
K
Y
L
R
Site 105
Y1267
R
R
S
H
L
E
K
Y
L
R
D
F
F
S
V
Site 106
S1273
K
Y
L
R
D
F
F
S
V
M
L
Q
S
A
T
Site 107
T1291
H
I
N
K
V
G
L
T
L
S
K
H
T
I
C
Site 108
S1293
N
K
V
G
L
T
L
S
K
H
T
I
C
E
F
Site 109
Y1311
F
K
K
G
V
F
D
Y
S
S
H
G
T
G
_
Site 110
S1312
K
K
G
V
F
D
Y
S
S
H
G
T
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation