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Updated November 2019
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Protein Info
Short Name:
POM121L2
Full Name:
POM121-like protein 2
Alias:
PO122; POM121 membrane glycoprotein-like 2; POM121L; POM121-L; POM121-like 2
Type:
Mass (Da):
103081
Number AA:
971
UniProt ID:
Q96KW2
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
S
F
L
S
K
L
E
L
S
P
S
Site 2
S11
F
L
S
K
L
E
L
S
P
S
S
P
A
Q
V
Site 3
S13
S
K
L
E
L
S
P
S
S
P
A
Q
V
R
T
Site 4
S14
K
L
E
L
S
P
S
S
P
A
Q
V
R
T
D
Site 5
T20
S
S
P
A
Q
V
R
T
D
L
P
E
R
P
T
Site 6
T27
T
D
L
P
E
R
P
T
K
R
R
P
P
Q
P
Site 7
Y53
R
A
H
P
A
P
R
Y
R
P
V
R
R
R
P
Site 8
S84
R
R
F
P
M
K
K
S
Q
N
S
P
L
G
P
Site 9
S87
P
M
K
K
S
Q
N
S
P
L
G
P
L
P
S
Site 10
S94
S
P
L
G
P
L
P
S
D
W
W
E
S
Y
L
Site 11
S99
L
P
S
D
W
W
E
S
Y
L
K
R
T
I
W
Site 12
S107
Y
L
K
R
T
I
W
S
L
R
H
P
R
P
I
Site 13
S116
R
H
P
R
P
I
W
S
P
V
T
I
R
I
T
Site 14
T119
R
P
I
W
S
P
V
T
I
R
I
T
P
P
D
Site 15
T123
S
P
V
T
I
R
I
T
P
P
D
Q
R
V
P
Site 16
S132
P
D
Q
R
V
P
P
S
T
S
P
E
D
V
I
Site 17
T133
D
Q
R
V
P
P
S
T
S
P
E
D
V
I
A
Site 18
S134
Q
R
V
P
P
S
T
S
P
E
D
V
I
A
L
Site 19
S155
E
E
L
A
D
P
C
S
K
E
T
V
L
R
A
Site 20
S181
E
E
P
L
F
P
E
S
L
D
S
K
R
R
S
Site 21
S184
L
F
P
E
S
L
D
S
K
R
R
S
P
E
T
Site 22
S188
S
L
D
S
K
R
R
S
P
E
T
R
P
S
A
Site 23
T191
S
K
R
R
S
P
E
T
R
P
S
A
F
K
P
Site 24
S194
R
S
P
E
T
R
P
S
A
F
K
P
L
M
K
Site 25
T204
K
P
L
M
K
N
G
T
L
T
S
F
V
P
R
Site 26
S207
M
K
N
G
T
L
T
S
F
V
P
R
P
G
P
Site 27
S218
R
P
G
P
L
K
R
S
L
H
S
W
G
S
D
Site 28
S221
P
L
K
R
S
L
H
S
W
G
S
D
H
S
L
Site 29
S224
R
S
L
H
S
W
G
S
D
H
S
L
T
K
R
Site 30
S227
H
S
W
G
S
D
H
S
L
T
K
R
P
N
C
Site 31
T229
W
G
S
D
H
S
L
T
K
R
P
N
C
S
S
Site 32
S235
L
T
K
R
P
N
C
S
S
M
S
S
L
A
S
Site 33
S236
T
K
R
P
N
C
S
S
M
S
S
L
A
S
I
Site 34
S238
R
P
N
C
S
S
M
S
S
L
A
S
I
Y
R
Site 35
S239
P
N
C
S
S
M
S
S
L
A
S
I
Y
R
G
Site 36
S242
S
S
M
S
S
L
A
S
I
Y
R
G
G
T
L
Site 37
T248
A
S
I
Y
R
G
G
T
L
S
S
K
R
N
A
Site 38
S250
I
Y
R
G
G
T
L
S
S
K
R
N
A
I
G
Site 39
S251
Y
R
G
G
T
L
S
S
K
R
N
A
I
G
S
Site 40
S258
S
K
R
N
A
I
G
S
S
Y
S
S
C
R
N
Site 41
S259
K
R
N
A
I
G
S
S
Y
S
S
C
R
N
F
Site 42
Y260
R
N
A
I
G
S
S
Y
S
S
C
R
N
F
S
Site 43
S261
N
A
I
G
S
S
Y
S
S
C
R
N
F
S
D
Site 44
S262
A
I
G
S
S
Y
S
S
C
R
N
F
S
D
P
Site 45
S267
Y
S
S
C
R
N
F
S
D
P
W
K
R
S
V
Site 46
S273
F
S
D
P
W
K
R
S
V
P
S
V
S
F
E
Site 47
S276
P
W
K
R
S
V
P
S
V
S
F
E
T
P
E
Site 48
S278
K
R
S
V
P
S
V
S
F
E
T
P
E
W
P
Site 49
T281
V
P
S
V
S
F
E
T
P
E
W
P
I
K
K
Site 50
S291
W
P
I
K
K
E
K
S
C
H
R
P
S
S
P
Site 51
S296
E
K
S
C
H
R
P
S
S
P
V
P
L
V
S
Site 52
S297
K
S
C
H
R
P
S
S
P
V
P
L
V
S
D
Site 53
S307
P
L
V
S
D
F
E
S
L
G
G
S
E
S
S
Site 54
S311
D
F
E
S
L
G
G
S
E
S
S
G
Q
Q
N
Site 55
S313
E
S
L
G
G
S
E
S
S
G
Q
Q
N
Q
K
Site 56
S327
K
I
P
Q
L
P
S
S
P
E
N
L
V
S
E
Site 57
S333
S
S
P
E
N
L
V
S
E
I
P
P
P
Q
L
Site 58
S345
P
Q
L
G
Y
A
V
S
D
E
N
L
T
L
G
Site 59
S359
G
K
K
A
E
L
Q
S
T
G
E
A
T
S
V
Site 60
T360
K
K
A
E
L
Q
S
T
G
E
A
T
S
V
A
Site 61
S365
Q
S
T
G
E
A
T
S
V
A
H
S
P
L
K
Site 62
S369
E
A
T
S
V
A
H
S
P
L
K
T
P
S
L
Site 63
T373
V
A
H
S
P
L
K
T
P
S
L
P
T
P
P
Site 64
S375
H
S
P
L
K
T
P
S
L
P
T
P
P
G
C
Site 65
T378
L
K
T
P
S
L
P
T
P
P
G
C
S
Q
S
Site 66
S383
L
P
T
P
P
G
C
S
Q
S
E
L
L
P
G
Site 67
S385
T
P
P
G
C
S
Q
S
E
L
L
P
G
T
S
Site 68
T391
Q
S
E
L
L
P
G
T
S
P
D
S
K
P
T
Site 69
S392
S
E
L
L
P
G
T
S
P
D
S
K
P
T
A
Site 70
S395
L
P
G
T
S
P
D
S
K
P
T
A
T
F
I
Site 71
T400
P
D
S
K
P
T
A
T
F
I
L
L
T
P
T
Site 72
T414
T
S
P
T
L
P
V
T
D
T
T
W
P
P
S
Site 73
T416
P
T
L
P
V
T
D
T
T
W
P
P
S
T
S
Site 74
T417
T
L
P
V
T
D
T
T
W
P
P
S
T
S
Q
Site 75
S421
T
D
T
T
W
P
P
S
T
S
Q
A
D
R
S
Site 76
S423
T
T
W
P
P
S
T
S
Q
A
D
R
S
P
M
Site 77
S428
S
T
S
Q
A
D
R
S
P
M
P
P
D
P
P
Site 78
T439
P
D
P
P
A
P
P
T
I
Q
S
T
L
L
G
Site 79
S453
G
M
V
S
S
P
T
S
H
L
S
A
S
A
P
Site 80
S456
S
S
P
T
S
H
L
S
A
S
A
P
P
D
A
Site 81
S458
P
T
S
H
L
S
A
S
A
P
P
D
A
T
S
Site 82
S465
S
A
P
P
D
A
T
S
A
H
L
M
L
K
P
Site 83
S480
I
L
G
P
L
H
N
S
E
I
G
S
S
S
Y
Site 84
S484
L
H
N
S
E
I
G
S
S
S
Y
S
R
I
S
Site 85
S485
H
N
S
E
I
G
S
S
S
Y
S
R
I
S
V
Site 86
S486
N
S
E
I
G
S
S
S
Y
S
R
I
S
V
T
Site 87
Y487
S
E
I
G
S
S
S
Y
S
R
I
S
V
T
A
Site 88
S488
E
I
G
S
S
S
Y
S
R
I
S
V
T
A
A
Site 89
S491
S
S
S
Y
S
R
I
S
V
T
A
A
A
S
S
Site 90
T508
S
L
S
T
I
Q
G
T
L
T
P
T
F
K
P
Site 91
S519
T
F
K
P
I
F
G
S
I
D
P
L
K
T
T
Site 92
S533
T
P
M
I
A
P
F
S
S
K
Q
T
P
P
P
Site 93
S534
P
M
I
A
P
F
S
S
K
Q
T
P
P
P
F
Site 94
T537
A
P
F
S
S
K
Q
T
P
P
P
F
T
H
A
Site 95
T542
K
Q
T
P
P
P
F
T
H
A
S
T
H
H
F
Site 96
T563
T
S
V
V
M
S
T
T
L
A
S
T
S
K
D
Site 97
S571
L
A
S
T
S
K
D
S
V
F
K
P
P
L
D
Site 98
Y592
T
S
A
V
G
N
T
Y
S
V
P
S
T
C
D
Site 99
S593
S
A
V
G
N
T
Y
S
V
P
S
T
C
D
T
Site 100
T617
R
A
D
F
T
P
A
T
G
F
I
F
P
P
H
Site 101
S649
L
S
S
V
V
Q
I
S
P
R
S
S
T
A
N
Site 102
S652
V
V
Q
I
S
P
R
S
S
T
A
N
F
R
G
Site 103
S653
V
Q
I
S
P
R
S
S
T
A
N
F
R
G
M
Site 104
T654
Q
I
S
P
R
S
S
T
A
N
F
R
G
M
G
Site 105
T678
S
T
N
W
L
A
S
T
P
S
I
S
N
L
T
Site 106
S680
N
W
L
A
S
T
P
S
I
S
N
L
T
P
A
Site 107
T689
S
N
L
T
P
A
I
T
S
P
L
G
S
S
S
Site 108
S690
N
L
T
P
A
I
T
S
P
L
G
S
S
S
R
Site 109
S694
A
I
T
S
P
L
G
S
S
S
R
P
P
F
P
Site 110
S695
I
T
S
P
L
G
S
S
S
R
P
P
F
P
L
Site 111
S696
T
S
P
L
G
S
S
S
R
P
P
F
P
L
S
Site 112
S703
S
R
P
P
F
P
L
S
Q
G
A
N
P
Q
P
Site 113
S723
N
G
Q
K
Q
G
P
S
Q
P
A
L
M
P
S
Site 114
T768
Q
S
A
L
G
C
L
T
P
S
A
S
T
S
Q
Site 115
S770
A
L
G
C
L
T
P
S
A
S
T
S
Q
T
P
Site 116
S772
G
C
L
T
P
S
A
S
T
S
Q
T
P
A
S
Site 117
S774
L
T
P
S
A
S
T
S
Q
T
P
A
S
T
W
Site 118
T776
P
S
A
S
T
S
Q
T
P
A
S
T
W
S
G
Site 119
S779
S
T
S
Q
T
P
A
S
T
W
S
G
I
G
G
Site 120
S815
H
Q
S
G
A
F
G
S
V
F
G
S
R
A
P
Site 121
S819
A
F
G
S
V
F
G
S
R
A
P
Q
P
F
T
Site 122
T826
S
R
A
P
Q
P
F
T
F
G
G
F
V
T
P
Site 123
S849
I
M
T
G
P
D
M
S
P
T
S
G
A
F
S
Site 124
T851
T
G
P
D
M
S
P
T
S
G
A
F
S
I
G
Site 125
S852
G
P
D
M
S
P
T
S
G
A
F
S
I
G
A
Site 126
T867
L
P
S
G
T
T
N
T
M
I
P
F
G
K
G
Site 127
S876
I
P
F
G
K
G
W
S
Q
N
T
E
G
L
P
Site 128
S884
Q
N
T
E
G
L
P
S
H
R
T
A
F
S
L
Site 129
T887
E
G
L
P
S
H
R
T
A
F
S
L
G
R
G
Site 130
S890
P
S
H
R
T
A
F
S
L
G
R
G
S
I
S
Site 131
S895
A
F
S
L
G
R
G
S
I
S
A
R
K
T
M
Site 132
S897
S
L
G
R
G
S
I
S
A
R
K
T
M
A
P
Site 133
T901
G
S
I
S
A
R
K
T
M
A
P
I
A
Q
N
Site 134
T909
M
A
P
I
A
Q
N
T
P
V
P
G
Q
A
K
Site 135
S919
P
G
Q
A
K
A
G
S
S
V
G
F
G
M
P
Site 136
S933
P
F
P
P
A
Q
G
S
V
G
R
G
P
F
R
Site 137
S941
V
G
R
G
P
F
R
S
S
A
S
S
F
S
I
Site 138
S942
G
R
G
P
F
R
S
S
A
S
S
F
S
I
G
Site 139
S944
G
P
F
R
S
S
A
S
S
F
S
I
G
A
K
Site 140
S945
P
F
R
S
S
A
S
S
F
S
I
G
A
K
S
Site 141
S947
R
S
S
A
S
S
F
S
I
G
A
K
S
K
T
Site 142
S952
S
F
S
I
G
A
K
S
K
T
P
K
N
R
E
Site 143
T954
S
I
G
A
K
S
K
T
P
K
N
R
E
K
G
Site 144
S963
K
N
R
E
K
G
H
S
R
R
H
H
A
Y
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation