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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFR
Full Name:
Zinc finger RNA-binding protein
Alias:
ZFR1; zinc finger RNA binding protein; zinc finger RNA-binding
Type:
RNA binding protein
Mass (Da):
117012
Number AA:
1074
UniProt ID:
Q96KR1
International Prot ID:
IPI00333858
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
I
P
I
C
P
V
V
S
F
T
Y
V
P
S
R
Site 2
Y28
A
K
M
A
T
G
N
Y
F
G
F
T
H
S
G
Site 3
S46
A
A
A
A
A
Q
Y
S
Q
Q
P
A
S
G
V
Site 4
S51
Q
Y
S
Q
Q
P
A
S
G
V
A
Y
S
H
P
Site 5
Y55
Q
P
A
S
G
V
A
Y
S
H
P
T
T
V
A
Site 6
S56
P
A
S
G
V
A
Y
S
H
P
T
T
V
A
S
Site 7
T60
V
A
Y
S
H
P
T
T
V
A
S
Y
T
V
H
Site 8
S63
S
H
P
T
T
V
A
S
Y
T
V
H
Q
A
P
Site 9
Y109
T
A
A
A
Y
G
G
Y
P
T
A
H
T
A
T
Site 10
T114
G
G
Y
P
T
A
H
T
A
T
D
Y
G
Y
T
Site 11
Y118
T
A
H
T
A
T
D
Y
G
Y
T
Q
R
Q
Q
Site 12
Y120
H
T
A
T
D
Y
G
Y
T
Q
R
Q
Q
E
A
Site 13
T135
P
P
P
P
P
P
A
T
T
Q
N
Y
Q
D
S
Site 14
Y139
P
P
A
T
T
Q
N
Y
Q
D
S
Y
S
Y
V
Site 15
S142
T
T
Q
N
Y
Q
D
S
Y
S
Y
V
R
S
T
Site 16
Y143
T
Q
N
Y
Q
D
S
Y
S
Y
V
R
S
T
A
Site 17
S144
Q
N
Y
Q
D
S
Y
S
Y
V
R
S
T
A
P
Site 18
Y145
N
Y
Q
D
S
Y
S
Y
V
R
S
T
A
P
A
Site 19
S148
D
S
Y
S
Y
V
R
S
T
A
P
A
V
A
Y
Site 20
T149
S
Y
S
Y
V
R
S
T
A
P
A
V
A
Y
D
Site 21
Y155
S
T
A
P
A
V
A
Y
D
S
K
Q
Y
Y
Q
Site 22
S157
A
P
A
V
A
Y
D
S
K
Q
Y
Y
Q
Q
P
Site 23
Y161
A
Y
D
S
K
Q
Y
Y
Q
Q
P
T
A
T
A
Site 24
S180
A
A
A
Q
P
Q
P
S
V
A
E
T
Y
Y
Q
Site 25
T184
P
Q
P
S
V
A
E
T
Y
Y
Q
T
A
P
K
Site 26
Y186
P
S
V
A
E
T
Y
Y
Q
T
A
P
K
A
G
Site 27
Y194
Q
T
A
P
K
A
G
Y
S
Q
G
A
T
Q
Y
Site 28
S195
T
A
P
K
A
G
Y
S
Q
G
A
T
Q
Y
T
Site 29
T199
A
G
Y
S
Q
G
A
T
Q
Y
T
Q
A
Q
Q
Site 30
Y201
Y
S
Q
G
A
T
Q
Y
T
Q
A
Q
Q
T
R
Site 31
T211
A
Q
Q
T
R
Q
V
T
A
I
K
P
A
T
P
Site 32
T217
V
T
A
I
K
P
A
T
P
S
P
A
T
T
T
Site 33
S219
A
I
K
P
A
T
P
S
P
A
T
T
T
F
S
Site 34
T222
P
A
T
P
S
P
A
T
T
T
F
S
I
Y
P
Site 35
T224
T
P
S
P
A
T
T
T
F
S
I
Y
P
V
S
Site 36
S226
S
P
A
T
T
T
F
S
I
Y
P
V
S
S
T
Site 37
Y247
A
A
T
V
V
P
S
Y
T
Q
S
A
T
Y
S
Site 38
S250
V
V
P
S
Y
T
Q
S
A
T
Y
S
T
T
A
Site 39
S254
Y
T
Q
S
A
T
Y
S
T
T
A
V
T
Y
S
Site 40
S261
S
T
T
A
V
T
Y
S
G
T
S
Y
S
G
Y
Site 41
Y265
V
T
Y
S
G
T
S
Y
S
G
Y
E
A
A
V
Site 42
Y268
S
G
T
S
Y
S
G
Y
E
A
A
V
Y
S
A
Site 43
Y273
S
G
Y
E
A
A
V
Y
S
A
A
S
S
Y
Y
Site 44
S274
G
Y
E
A
A
V
Y
S
A
A
S
S
Y
Y
Q
Site 45
S278
A
V
Y
S
A
A
S
S
Y
Y
Q
Q
Q
Q
Q
Site 46
T307
T
A
A
W
T
G
T
T
F
T
K
K
A
P
F
Site 47
Y332
P
K
P
P
Q
I
H
Y
C
D
V
C
K
I
S
Site 48
T345
I
S
C
A
G
P
Q
T
Y
K
E
H
L
E
G
Site 49
Y346
S
C
A
G
P
Q
T
Y
K
E
H
L
E
G
Q
Site 50
S365
K
E
A
A
L
K
A
S
Q
N
T
S
S
S
N
Site 51
S369
L
K
A
S
Q
N
T
S
S
S
N
S
S
T
R
Site 52
S370
K
A
S
Q
N
T
S
S
S
N
S
S
T
R
G
Site 53
S371
A
S
Q
N
T
S
S
S
N
S
S
T
R
G
T
Site 54
S373
Q
N
T
S
S
S
N
S
S
T
R
G
T
Q
N
Site 55
S374
N
T
S
S
S
N
S
S
T
R
G
T
Q
N
Q
Site 56
T375
T
S
S
S
N
S
S
T
R
G
T
Q
N
Q
L
Site 57
T378
S
N
S
S
T
R
G
T
Q
N
Q
L
R
C
E
Site 58
Y397
S
C
T
G
A
D
A
Y
A
A
H
I
R
G
A
Site 59
T423
L
G
K
P
I
P
S
T
E
P
N
V
V
S
Q
Site 60
S429
S
T
E
P
N
V
V
S
Q
A
T
S
S
T
A
Site 61
S438
A
T
S
S
T
A
V
S
A
S
K
P
T
A
S
Site 62
S440
S
S
T
A
V
S
A
S
K
P
T
A
S
P
S
Site 63
T443
A
V
S
A
S
K
P
T
A
S
P
S
S
I
A
Site 64
S445
S
A
S
K
P
T
A
S
P
S
S
I
A
A
N
Site 65
S447
S
K
P
T
A
S
P
S
S
I
A
A
N
N
C
Site 66
S448
K
P
T
A
S
P
S
S
I
A
A
N
N
C
T
Site 67
S460
N
C
T
V
N
T
S
S
V
A
T
S
S
M
K
Site 68
S464
N
T
S
S
V
A
T
S
S
M
K
G
L
T
T
Site 69
S465
T
S
S
V
A
T
S
S
M
K
G
L
T
T
T
Site 70
T470
T
S
S
M
K
G
L
T
T
T
G
N
S
S
L
Site 71
T471
S
S
M
K
G
L
T
T
T
G
N
S
S
L
N
Site 72
T472
S
M
K
G
L
T
T
T
G
N
S
S
L
N
S
Site 73
S475
G
L
T
T
T
G
N
S
S
L
N
S
T
S
N
Site 74
S476
L
T
T
T
G
N
S
S
L
N
S
T
S
N
T
Site 75
S479
T
G
N
S
S
L
N
S
T
S
N
T
K
V
S
Site 76
T480
G
N
S
S
L
N
S
T
S
N
T
K
V
S
A
Site 77
S481
N
S
S
L
N
S
T
S
N
T
K
V
S
A
V
Site 78
T483
S
L
N
S
T
S
N
T
K
V
S
A
V
P
T
Site 79
S486
S
T
S
N
T
K
V
S
A
V
P
T
N
M
A
Site 80
T499
M
A
A
K
K
T
S
T
P
K
I
N
F
V
G
Site 81
S528
K
G
T
E
C
V
K
S
T
P
V
T
S
A
V
Site 82
T529
G
T
E
C
V
K
S
T
P
V
T
S
A
V
Q
Site 83
T544
I
P
E
V
K
Q
D
T
V
S
E
P
V
T
P
Site 84
S546
E
V
K
Q
D
T
V
S
E
P
V
T
P
A
S
Site 85
T550
D
T
V
S
E
P
V
T
P
A
S
L
A
A
L
Site 86
S553
S
E
P
V
T
P
A
S
L
A
A
L
Q
S
D
Site 87
Y568
V
Q
P
V
G
H
D
Y
V
E
E
V
R
N
D
Site 88
Y610
G
R
R
H
R
L
Q
Y
K
K
K
V
N
P
D
Site 89
S625
L
Q
V
E
V
K
P
S
I
R
A
R
K
I
Q
Site 90
Y645
K
Q
M
Q
K
E
E
Y
W
R
R
R
E
E
E
Site 91
Y667
R
R
Y
E
E
D
M
Y
W
R
R
M
E
E
E
Site 92
Y689
R
R
M
P
D
G
G
Y
P
H
G
P
P
G
P
Site 93
S721
A
P
L
R
R
P
D
S
S
D
D
R
Y
V
M
Site 94
S722
P
L
R
R
P
D
S
S
D
D
R
Y
V
M
T
Site 95
Y726
P
D
S
S
D
D
R
Y
V
M
T
K
H
A
T
Site 96
Y735
M
T
K
H
A
T
I
Y
P
T
E
E
E
L
Q
Site 97
S759
E
R
A
L
K
L
V
S
D
S
L
S
E
H
E
Site 98
S761
A
L
K
L
V
S
D
S
L
S
E
H
E
K
N
Site 99
S763
K
L
V
S
D
S
L
S
E
H
E
K
N
K
N
Site 100
S817
L
L
C
S
E
K
P
S
K
T
L
L
S
R
I
Site 101
T819
C
S
E
K
P
S
K
T
L
L
S
R
I
A
E
Site 102
S822
K
P
S
K
T
L
L
S
R
I
A
E
N
L
P
Site 103
S836
P
K
Q
L
A
V
I
S
P
E
K
Y
D
I
K
Site 104
S869
Q
V
T
I
T
L
T
S
P
I
I
R
E
E
N
Site 105
T883
N
M
R
E
G
D
V
T
S
G
M
V
K
D
P
Site 106
S884
M
R
E
G
D
V
T
S
G
M
V
K
D
P
P
Site 107
T938
D
L
C
Q
R
V
P
T
W
S
D
F
P
S
W
Site 108
S956
L
L
V
E
K
A
I
S
S
A
S
S
P
Q
S
Site 109
S957
L
V
E
K
A
I
S
S
A
S
S
P
Q
S
P
Site 110
S959
E
K
A
I
S
S
A
S
S
P
Q
S
P
G
D
Site 111
S960
K
A
I
S
S
A
S
S
P
Q
S
P
G
D
A
Site 112
S963
S
S
A
S
S
P
Q
S
P
G
D
A
L
R
R
Site 113
S1012
Q
Q
R
E
D
I
T
S
S
A
Q
F
A
L
R
Site 114
S1054
N
R
K
R
R
R
D
S
D
G
V
D
G
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation