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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PKNOX2
Full Name:
Homeobox protein PKNOX2
Alias:
Homeobox protein PREP-2;PBX/knotted homeobox 2
Type:
Mass (Da):
52028
Number AA:
472
UniProt ID:
Q96KN3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
P
A
L
T
M
M
A
T
Q
N
V
P
P
P
P
Site 2
Y24
Q
N
V
P
P
P
P
Y
Q
D
S
P
Q
M
T
Site 3
S27
P
P
P
P
Y
Q
D
S
P
Q
M
T
A
T
A
Site 4
T31
Y
Q
D
S
P
Q
M
T
A
T
A
Q
P
P
S
Site 5
T33
D
S
P
Q
M
T
A
T
A
Q
P
P
S
K
A
Site 6
S38
T
A
T
A
Q
P
P
S
K
A
Q
A
V
H
I
Site 7
S53
S
A
P
S
A
A
A
S
T
P
V
P
S
A
P
Site 8
S58
A
A
S
T
P
V
P
S
A
P
I
D
P
Q
A
Site 9
Y75
E
A
D
K
R
A
V
Y
R
H
P
L
F
P
L
Site 10
T94
F
E
K
C
E
Q
A
T
Q
G
S
E
C
I
T
Site 11
S97
C
E
Q
A
T
Q
G
S
E
C
I
T
S
A
S
Site 12
T101
T
Q
G
S
E
C
I
T
S
A
S
F
D
V
D
Site 13
S102
Q
G
S
E
C
I
T
S
A
S
F
D
V
D
I
Site 14
S104
S
E
C
I
T
S
A
S
F
D
V
D
I
E
N
Site 15
S125
Q
E
H
K
P
F
F
S
D
D
P
E
L
D
N
Site 16
Y162
C
K
D
F
C
N
R
Y
I
T
C
L
K
T
K
Site 17
Y184
R
N
D
L
G
G
P
Y
S
P
N
Q
P
S
I
Site 18
S185
N
D
L
G
G
P
Y
S
P
N
Q
P
S
I
N
Site 19
S190
P
Y
S
P
N
Q
P
S
I
N
L
H
S
Q
D
Site 20
S195
Q
P
S
I
N
L
H
S
Q
D
L
L
Q
N
S
Site 21
S202
S
Q
D
L
L
Q
N
S
P
N
S
M
S
G
V
Site 22
S205
L
L
Q
N
S
P
N
S
M
S
G
V
S
N
N
Site 23
S207
Q
N
S
P
N
S
M
S
G
V
S
N
N
P
Q
Site 24
S210
P
N
S
M
S
G
V
S
N
N
P
Q
G
I
V
Site 25
T231
Q
Q
G
N
I
A
M
T
T
V
N
S
Q
V
V
Site 26
S239
T
V
N
S
Q
V
V
S
G
G
A
L
Y
Q
P
Site 27
T248
G
A
L
Y
Q
P
V
T
M
V
T
S
Q
G
Q
Site 28
S279
Q
V
N
L
D
L
T
S
L
L
D
N
E
D
K
Site 29
S288
L
D
N
E
D
K
K
S
K
N
K
R
G
V
L
Site 30
Y315
F
Q
H
L
M
H
P
Y
P
T
E
D
E
K
R
Site 31
S354
L
Q
P
M
L
D
A
S
N
P
D
P
A
P
K
Site 32
S367
P
K
A
K
K
I
K
S
Q
H
R
P
T
Q
R
Site 33
T372
I
K
S
Q
H
R
P
T
Q
R
F
W
P
N
S
Site 34
S379
T
Q
R
F
W
P
N
S
I
A
A
G
V
L
Q
Site 35
T394
Q
Q
G
G
A
P
G
T
N
P
D
G
S
I
N
Site 36
S399
P
G
T
N
P
D
G
S
I
N
L
D
N
L
Q
Site 37
S407
I
N
L
D
N
L
Q
S
L
S
S
D
S
A
T
Site 38
S409
L
D
N
L
Q
S
L
S
S
D
S
A
T
M
A
Site 39
S410
D
N
L
Q
S
L
S
S
D
S
A
T
M
A
M
Site 40
S412
L
Q
S
L
S
S
D
S
A
T
M
A
M
Q
Q
Site 41
T414
S
L
S
S
D
S
A
T
M
A
M
Q
Q
A
M
Site 42
S428
M
M
A
A
H
D
D
S
L
D
G
T
E
E
E
Site 43
T432
H
D
D
S
L
D
G
T
E
E
E
D
E
D
E
Site 44
T458
E
V
D
E
L
Q
T
T
N
V
S
D
L
G
L
Site 45
S461
E
L
Q
T
T
N
V
S
D
L
G
L
E
H
S
Site 46
S468
S
D
L
G
L
E
H
S
D
S
L
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation