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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FEM1C
Full Name:
Protein fem-1 homolog C
Alias:
FEM1-gamma
Type:
Mass (Da):
68673
Number AA:
617
UniProt ID:
Q96JP0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
D
G
K
L
R
L
L
T
K
L
L
A
S
K
S
Site 2
S25
L
L
T
K
L
L
A
S
K
S
K
E
E
V
S
Site 3
S27
T
K
L
L
A
S
K
S
K
E
E
V
S
S
L
Site 4
S32
S
K
S
K
E
E
V
S
S
L
I
S
E
K
T
Site 5
S33
K
S
K
E
E
V
S
S
L
I
S
E
K
T
N
Site 6
S36
E
E
V
S
S
L
I
S
E
K
T
N
G
A
T
Site 7
T39
S
S
L
I
S
E
K
T
N
G
A
T
P
L
L
Site 8
T43
S
E
K
T
N
G
A
T
P
L
L
M
A
A
R
Site 9
S73
A
S
I
E
V
G
G
S
V
N
F
D
G
E
T
Site 10
T80
S
V
N
F
D
G
E
T
I
E
G
A
P
P
L
Site 11
S101
G
H
L
K
V
V
Q
S
L
L
N
H
G
A
S
Site 12
S108
S
L
L
N
H
G
A
S
V
N
N
T
T
L
T
Site 13
T112
H
G
A
S
V
N
N
T
T
L
T
N
S
T
P
Site 14
T113
G
A
S
V
N
N
T
T
L
T
N
S
T
P
L
Site 15
T115
S
V
N
N
T
T
L
T
N
S
T
P
L
R
A
Site 16
T118
N
T
T
L
T
N
S
T
P
L
R
A
A
C
F
Site 17
Y134
G
H
L
E
I
V
K
Y
L
V
E
H
K
A
D
Site 18
Y167
G
H
K
E
I
A
Q
Y
L
L
E
K
G
A
D
Site 19
S179
G
A
D
V
N
R
K
S
V
K
G
N
T
A
L
Site 20
Y213
A
K
M
E
K
D
G
Y
G
M
T
P
L
L
S
Site 21
T216
E
K
D
G
Y
G
M
T
P
L
L
S
A
S
V
Site 22
T234
T
N
I
V
D
F
L
T
H
H
A
Q
T
S
K
Site 23
T242
H
H
A
Q
T
S
K
T
E
R
I
N
A
L
E
Site 24
T254
A
L
E
L
L
G
A
T
F
V
D
K
K
R
D
Site 25
Y268
D
L
L
G
A
L
K
Y
W
K
K
A
M
N
M
Site 26
Y277
K
K
A
M
N
M
R
Y
S
D
R
T
N
I
I
Site 27
S278
K
A
M
N
M
R
Y
S
D
R
T
N
I
I
S
Site 28
T281
N
M
R
Y
S
D
R
T
N
I
I
S
K
P
V
Site 29
S285
S
D
R
T
N
I
I
S
K
P
V
P
Q
T
L
Site 30
Y298
T
L
I
M
A
Y
D
Y
A
K
E
V
N
S
A
Site 31
S333
R
E
R
I
L
G
P
S
H
P
D
T
S
Y
Y
Site 32
T337
L
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
Site 33
S338
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Site 34
Y339
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
A
Site 35
Y340
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
A
V
Site 36
Y348
I
R
Y
R
G
A
V
Y
A
D
S
G
N
F
K
Site 37
S351
R
G
A
V
Y
A
D
S
G
N
F
K
R
C
I
Site 38
Y363
R
C
I
N
L
W
K
Y
A
L
D
M
Q
Q
S
Site 39
S370
Y
A
L
D
M
Q
Q
S
N
L
D
P
L
S
P
Site 40
S376
Q
S
N
L
D
P
L
S
P
M
T
A
S
S
L
Site 41
T429
I
E
R
A
I
K
Q
T
Q
C
P
A
D
P
L
Site 42
T458
L
L
E
K
V
P
C
T
L
E
Q
D
H
F
K
Site 43
T468
Q
D
H
F
K
K
Q
T
I
Y
R
F
L
K
L
Site 44
Y470
H
F
K
K
Q
T
I
Y
R
F
L
K
L
H
P
Site 45
S484
P
R
G
K
N
N
F
S
P
L
H
L
A
V
D
Site 46
T494
H
L
A
V
D
K
N
T
T
C
V
G
R
Y
P
Site 47
Y500
N
T
T
C
V
G
R
Y
P
V
C
K
F
P
S
Site 48
S526
A
D
V
N
V
R
D
S
D
D
N
S
P
L
H
Site 49
S530
V
R
D
S
D
D
N
S
P
L
H
I
A
A
L
Site 50
T557
S
G
A
H
F
D
A
T
N
L
H
K
Q
T
A
Site 51
Y600
V
I
V
N
H
R
I
Y
Y
K
G
H
I
P
E
Site 52
Y601
I
V
N
H
R
I
Y
Y
K
G
H
I
P
E
K
Site 53
T611
H
I
P
E
K
L
E
T
F
V
S
L
H
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation