KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NEURL4
Full Name:
Neuralized-like protein 4
Alias:
NHR domain-containing protein KIAA1787
Type:
Mass (Da):
166907
Number AA:
1562
UniProt ID:
Q96JN8
International Prot ID:
IPI00064219
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
A
G
S
G
G
S
G
G
S
G
Site 2
S26
P
G
G
G
G
G
P
S
G
S
G
S
G
P
G
Site 3
S28
G
G
G
G
P
S
G
S
G
S
G
P
G
S
N
Site 4
S30
G
G
P
S
G
S
G
S
G
P
G
S
N
G
G
Site 5
S34
G
S
G
S
G
P
G
S
N
G
G
L
G
S
G
Site 6
S40
G
S
N
G
G
L
G
S
G
G
E
L
H
P
R
Site 7
T48
G
G
E
L
H
P
R
T
G
R
L
V
S
L
S
Site 8
S53
P
R
T
G
R
L
V
S
L
S
A
C
G
R
T
Site 9
S55
T
G
R
L
V
S
L
S
A
C
G
R
T
A
R
Site 10
T60
S
L
S
A
C
G
R
T
A
R
R
Q
Q
P
G
Site 11
S77
F
N
H
G
L
V
L
S
R
E
P
L
R
D
G
Site 12
T88
L
R
D
G
R
V
F
T
V
R
I
D
R
K
V
Site 13
S97
R
I
D
R
K
V
N
S
W
S
G
S
I
E
I
Site 14
S118
P
S
V
L
D
F
P
S
S
A
T
G
L
K
G
Site 15
S131
K
G
G
S
W
V
V
S
G
C
S
V
L
R
D
Site 16
S134
S
W
V
V
S
G
C
S
V
L
R
D
G
R
S
Site 17
S141
S
V
L
R
D
G
R
S
V
L
E
E
Y
G
Q
Site 18
T164
D
R
V
G
V
E
R
T
V
A
G
E
L
R
L
Site 19
T203
Y
G
K
C
T
Q
I
T
V
L
P
P
E
P
G
Site 20
S212
L
P
P
E
P
G
F
S
P
P
T
P
I
P
T
Site 21
T215
E
P
G
F
S
P
P
T
P
I
P
T
P
P
L
Site 22
T219
S
P
P
T
P
I
P
T
P
P
L
E
P
L
A
Site 23
S247
A
D
E
A
F
M
V
S
P
A
Q
A
R
P
E
Site 24
T255
P
A
Q
A
R
P
E
T
F
P
N
S
L
E
S
Site 25
S259
R
P
E
T
F
P
N
S
L
E
S
H
N
D
F
Site 26
S293
G
L
L
N
V
N
L
S
S
P
P
A
G
E
G
Site 27
S303
P
A
G
E
G
L
G
S
S
G
A
A
T
S
P
Site 28
S309
G
S
S
G
A
A
T
S
P
I
L
T
S
N
D
Site 29
T326
L
F
H
E
K
C
G
T
L
I
K
L
S
N
N
Site 30
S331
C
G
T
L
I
K
L
S
N
N
N
K
T
A
E
Site 31
T336
K
L
S
N
N
N
K
T
A
E
R
R
R
P
L
Site 32
T353
F
N
N
G
V
V
M
T
N
R
P
L
R
D
N
Site 33
S375
D
K
L
V
D
K
W
S
G
S
I
E
I
G
V
Site 34
T383
G
S
I
E
I
G
V
T
T
H
N
P
N
S
L
Site 35
T384
S
I
E
I
G
V
T
T
H
N
P
N
S
L
E
Site 36
S389
V
T
T
H
N
P
N
S
L
E
Y
P
A
T
M
Site 37
Y392
H
N
P
N
S
L
E
Y
P
A
T
M
T
N
L
Site 38
T395
N
S
L
E
Y
P
A
T
M
T
N
L
Q
S
G
Site 39
T413
M
S
G
C
G
I
L
T
N
G
K
G
T
R
R
Site 40
Y422
G
K
G
T
R
R
E
Y
C
E
F
S
L
D
E
Site 41
S426
R
R
E
Y
C
E
F
S
L
D
E
L
Q
E
G
Site 42
T439
E
G
D
H
I
G
L
T
R
K
S
N
S
A
L
Site 43
S442
H
I
G
L
T
R
K
S
N
S
A
L
H
F
F
Site 44
S502
N
A
I
L
R
A
L
S
P
E
G
A
L
R
R
Site 45
S556
F
N
H
G
V
V
L
S
S
R
A
L
R
D
G
Site 46
T587
S
I
E
I
G
V
T
T
H
N
P
A
Y
L
Q
Site 47
Y592
V
T
T
H
N
P
A
Y
L
Q
L
P
S
T
M
Site 48
S597
P
A
Y
L
Q
L
P
S
T
M
T
N
L
R
S
Site 49
T598
A
Y
L
Q
L
P
S
T
M
T
N
L
R
S
G
Site 50
T600
L
Q
L
P
S
T
M
T
N
L
R
S
G
T
W
Site 51
Y625
G
T
T
I
L
D
E
Y
G
H
N
L
D
R
L
Site 52
T637
D
R
L
K
A
G
D
T
V
G
V
V
R
R
E
Site 53
T647
V
V
R
R
E
D
G
T
L
H
F
F
V
N
G
Site 54
S704
P
E
G
N
N
Q
V
S
P
S
S
P
S
S
G
Site 55
S706
G
N
N
Q
V
S
P
S
S
P
S
S
G
A
G
Site 56
S707
N
N
Q
V
S
P
S
S
P
S
S
G
A
G
G
Site 57
S710
V
S
P
S
S
P
S
S
G
A
G
G
S
D
L
Site 58
S715
P
S
S
G
A
G
G
S
D
L
R
F
H
Q
L
Site 59
S725
R
F
H
Q
L
H
G
S
N
A
V
I
T
N
G
Site 60
S743
A
L
R
H
N
C
R
S
E
F
N
D
A
I
V
Site 61
S752
F
N
D
A
I
V
I
S
N
R
A
L
R
D
G
Site 62
S774
Q
K
M
V
D
R
W
S
G
S
I
E
A
G
V
Site 63
T794
E
D
L
E
F
P
N
T
M
T
D
I
D
Y
D
Site 64
Y800
N
T
M
T
D
I
D
Y
D
T
W
M
L
S
G
Site 65
T816
A
I
M
Q
D
G
N
T
M
R
N
N
Y
G
C
Site 66
Y821
G
N
T
M
R
N
N
Y
G
C
D
L
D
A
L
Site 67
T839
A
R
I
G
M
M
R
T
A
K
G
D
L
H
Y
Site 68
Y846
T
A
K
G
D
L
H
Y
F
I
N
G
Q
D
Q
Site 69
S858
Q
D
Q
G
A
A
C
S
G
L
P
P
G
K
E
Site 70
S891
A
T
G
P
M
D
N
S
L
A
T
S
N
T
A
Site 71
S895
M
D
N
S
L
A
T
S
N
T
A
T
E
K
S
Site 72
T897
N
S
L
A
T
S
N
T
A
T
E
K
S
F
P
Site 73
T899
L
A
T
S
N
T
A
T
E
K
S
F
P
L
H
Site 74
S902
S
N
T
A
T
E
K
S
F
P
L
H
S
P
V
Site 75
S907
E
K
S
F
P
L
H
S
P
V
A
G
V
A
H
Site 76
S918
G
V
A
H
R
F
H
S
T
C
G
K
N
V
T
Site 77
T925
S
T
C
G
K
N
V
T
L
E
E
D
G
T
R
Site 78
T931
V
T
L
E
E
D
G
T
R
A
V
R
A
A
G
Site 79
S970
L
D
E
K
W
A
G
S
L
R
L
G
L
T
T
Site 80
S997
G
G
P
G
L
P
P
S
L
P
E
L
R
T
K
Site 81
T1005
L
P
E
L
R
T
K
T
T
W
M
V
S
S
C
Site 82
T1006
P
E
L
R
T
K
T
T
W
M
V
S
S
C
E
Site 83
Y1025
G
Q
L
Q
R
M
N
Y
G
R
N
L
E
R
L
Site 84
S1036
L
E
R
L
G
V
G
S
R
V
G
V
R
R
G
Site 85
T1047
V
R
R
G
A
D
D
T
M
H
I
L
V
D
G
Site 86
S1086
R
G
V
S
I
V
S
S
T
R
L
E
E
S
E
Site 87
S1092
S
S
T
R
L
E
E
S
E
G
T
Q
P
P
S
Site 88
T1095
R
L
E
E
S
E
G
T
Q
P
P
S
P
S
S
Site 89
S1099
S
E
G
T
Q
P
P
S
P
S
S
D
T
G
S
Site 90
S1101
G
T
Q
P
P
S
P
S
S
D
T
G
S
E
G
Site 91
S1102
T
Q
P
P
S
P
S
S
D
T
G
S
E
G
E
Site 92
T1104
P
P
S
P
S
S
D
T
G
S
E
G
E
E
D
Site 93
S1106
S
P
S
S
D
T
G
S
E
G
E
E
D
D
E
Site 94
S1145
H
G
K
N
I
L
L
S
N
G
N
R
T
A
T
Site 95
T1152
S
N
G
N
R
T
A
T
R
V
A
S
Y
N
Q
Site 96
S1156
R
T
A
T
R
V
A
S
Y
N
Q
G
I
V
V
Site 97
S1206
E
R
L
N
F
P
A
S
A
C
A
L
K
R
A
Site 98
T1239
K
F
G
P
N
L
D
T
C
P
E
G
T
I
L
Site 99
S1303
P
G
A
A
S
G
K
S
A
G
T
Q
G
D
M
Site 100
S1332
W
G
P
P
P
A
A
S
P
L
K
S
C
E
Y
Site 101
S1336
P
A
A
S
P
L
K
S
C
E
Y
H
A
L
C
Site 102
Y1339
S
P
L
K
S
C
E
Y
H
A
L
C
S
R
F
Site 103
Y1356
L
L
L
L
P
E
D
Y
F
M
P
P
P
K
R
Site 104
S1370
R
S
L
C
Y
C
E
S
C
R
K
L
R
G
D
Site 105
Y1390
R
G
E
P
P
R
E
Y
A
L
P
F
G
W
C
Site 106
T1411
N
P
R
L
E
A
G
T
L
T
K
K
W
H
M
Site 107
S1446
A
G
T
A
S
I
L
S
C
R
P
L
K
G
E
Site 108
S1479
Q
P
P
P
V
L
L
S
P
S
L
Q
Y
A
G
Site 109
S1492
A
G
A
E
T
L
A
S
K
V
Q
F
R
D
P
Site 110
S1501
V
Q
F
R
D
P
K
S
Q
R
T
H
Q
A
Q
Site 111
S1519
Q
V
C
V
R
P
G
S
Y
T
P
G
P
P
S
Site 112
T1521
C
V
R
P
G
S
Y
T
P
G
P
P
S
A
A
Site 113
S1526
S
Y
T
P
G
P
P
S
A
A
L
G
E
P
P
Site 114
S1538
E
P
P
D
P
H
F
S
P
A
E
L
E
W
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation