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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDK5RAP3
Full Name:
CDK5 regulatory subunit-associated protein 3
Alias:
CDK5 activator-binding protein C53
Type:
Mass (Da):
56903
Number AA:
506
UniProt ID:
Q96JB5
International Prot ID:
IPI00414442
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0019899
PhosphoSite+
KinaseNET
Biological Process:
GO:0000079
GO:0007420
GO:0032502
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
L
V
D
R
R
H
C
S
L
K
W
Q
S
L
V
Site 2
S32
H
C
S
L
K
W
Q
S
L
V
L
T
I
R
E
Site 3
T36
K
W
Q
S
L
V
L
T
I
R
E
K
I
N
A
Site 4
S51
A
I
Q
D
M
P
E
S
E
E
I
A
Q
L
L
Site 5
Y104
W
Q
E
I
I
A
L
Y
E
K
D
N
T
Y
L
Site 6
T109
A
L
Y
E
K
D
N
T
Y
L
V
E
L
S
S
Site 7
Y110
L
Y
E
K
D
N
T
Y
L
V
E
L
S
S
L
Site 8
S115
N
T
Y
L
V
E
L
S
S
L
L
V
R
N
V
Site 9
S116
T
Y
L
V
E
L
S
S
L
L
V
R
N
V
N
Site 10
Y124
L
L
V
R
N
V
N
Y
E
I
P
S
L
K
K
Site 11
S144
Q
Q
L
Q
Q
E
Y
S
R
K
E
E
E
C
Q
Site 12
Y162
A
E
M
R
E
Q
F
Y
H
S
C
K
Q
Y
G
Site 13
S164
M
R
E
Q
F
Y
H
S
C
K
Q
Y
G
I
T
Site 14
Y168
F
Y
H
S
C
K
Q
Y
G
I
T
G
E
N
V
Site 15
S236
F
V
Q
K
R
G
N
S
T
V
Y
E
W
R
T
Site 16
Y239
K
R
G
N
S
T
V
Y
E
W
R
T
G
T
E
Site 17
T243
S
T
V
Y
E
W
R
T
G
T
E
P
S
V
V
Site 18
T245
V
Y
E
W
R
T
G
T
E
P
S
V
V
E
R
Site 19
S248
W
R
T
G
T
E
P
S
V
V
E
R
P
H
L
Site 20
S283
A
V
S
E
G
T
D
S
G
I
S
A
E
A
A
Site 21
S286
E
G
T
D
S
G
I
S
A
E
A
A
G
I
D
Site 22
S300
D
W
G
I
F
P
E
S
D
S
K
D
P
G
G
Site 23
S302
G
I
F
P
E
S
D
S
K
D
P
G
G
D
G
Site 24
T342
A
R
G
P
D
A
L
T
L
L
E
Y
T
E
T
Site 25
Y346
D
A
L
T
L
L
E
Y
T
E
T
R
N
Q
F
Site 26
T349
T
L
L
E
Y
T
E
T
R
N
Q
F
L
D
E
Site 27
S372
A
Q
R
A
V
E
L
S
E
E
A
D
V
L
S
Site 28
S379
S
E
E
A
D
V
L
S
V
S
Q
F
Q
L
A
Site 29
T394
P
A
I
L
Q
G
Q
T
K
E
K
M
V
T
M
Site 30
T400
Q
T
K
E
K
M
V
T
M
V
S
V
L
E
D
Site 31
T413
E
D
L
I
G
K
L
T
S
L
Q
L
Q
H
L
Site 32
T434
P
R
Y
V
D
R
V
T
E
F
L
Q
Q
K
L
Site 33
S444
L
Q
Q
K
L
K
Q
S
Q
L
L
A
L
K
K
Site 34
S491
K
L
I
E
A
D
I
S
K
R
Y
S
G
R
P
Site 35
S495
A
D
I
S
K
R
Y
S
G
R
P
V
N
L
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation