KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
COG3
Full Name:
Conserved oligomeric Golgi complex subunit 3
Alias:
p94; Vesicle docking protein SEC34
Type:
Vesicle protein
Mass (Da):
94096
Number AA:
828
UniProt ID:
Q96JB2
International Prot ID:
IPI00414858
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0017119
GO:0005801
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0006891
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
L
W
D
R
R
P
D
T
T
A
P
L
T
D
R
Site 2
T32
W
D
R
R
P
D
T
T
A
P
L
T
D
R
Q
Site 3
T36
P
D
T
T
A
P
L
T
D
R
Q
T
D
S
V
Site 4
T40
A
P
L
T
D
R
Q
T
D
S
V
L
E
L
K
Site 5
S42
L
T
D
R
Q
T
D
S
V
L
E
L
K
A
A
Site 6
S94
I
L
L
K
G
F
T
S
L
G
M
E
E
E
R
Site 7
T104
M
E
E
E
R
I
E
T
A
Q
Q
F
F
S
W
Site 8
Y127
D
Q
D
E
G
T
K
Y
R
Q
M
R
D
Y
L
Site 9
Y133
K
Y
R
Q
M
R
D
Y
L
S
G
F
Q
E
Q
Site 10
S150
A
I
L
N
D
V
N
S
A
L
Q
H
L
E
S
Site 11
S157
S
A
L
Q
H
L
E
S
L
Q
K
Q
Y
L
F
Site 12
Y162
L
E
S
L
Q
K
Q
Y
L
F
V
S
N
K
T
Site 13
S166
Q
K
Q
Y
L
F
V
S
N
K
T
G
T
L
H
Site 14
S184
E
Q
L
L
K
E
Q
S
E
L
V
D
L
A
E
Site 15
Y199
N
I
Q
Q
K
L
S
Y
F
N
E
L
E
T
I
Site 16
T208
N
E
L
E
T
I
N
T
K
L
N
S
P
T
L
Site 17
S212
T
I
N
T
K
L
N
S
P
T
L
S
V
N
S
Site 18
T214
N
T
K
L
N
S
P
T
L
S
V
N
S
D
G
Site 19
S216
K
L
N
S
P
T
L
S
V
N
S
D
G
F
I
Site 20
T234
A
K
L
D
D
C
I
T
Y
I
S
S
H
P
N
Site 21
Y235
K
L
D
D
C
I
T
Y
I
S
S
H
P
N
F
Site 22
Y245
S
H
P
N
F
K
D
Y
P
I
Y
L
L
K
F
Site 23
Y248
N
F
K
D
Y
P
I
Y
L
L
K
F
K
Q
C
Site 24
S257
L
K
F
K
Q
C
L
S
K
A
L
H
L
M
K
Site 25
T265
K
A
L
H
L
M
K
T
Y
T
V
N
T
L
Q
Site 26
S276
N
T
L
Q
T
L
T
S
Q
L
L
K
R
D
P
Site 27
S284
Q
L
L
K
R
D
P
S
S
V
P
N
A
D
N
Site 28
S285
L
L
K
R
D
P
S
S
V
P
N
A
D
N
A
Site 29
Y324
R
S
E
K
I
P
E
Y
Q
Q
L
L
N
D
I
Site 30
Y335
L
N
D
I
H
Q
C
Y
L
D
Q
R
E
L
L
Site 31
Y384
C
Q
D
E
H
Q
L
Y
N
E
F
F
T
K
P
Site 32
S393
E
F
F
T
K
P
T
S
K
L
D
E
L
L
E
Site 33
Y466
D
V
Q
E
R
L
V
Y
R
T
H
I
Y
I
Q
Site 34
T468
Q
E
R
L
V
Y
R
T
H
I
Y
I
Q
T
D
Site 35
T477
I
Y
I
Q
T
D
I
T
G
Y
K
P
A
P
G
Site 36
S511
D
E
Q
K
K
V
P
S
E
A
S
F
S
D
V
Site 37
S514
K
K
V
P
S
E
A
S
F
S
D
V
H
L
E
Site 38
S516
V
P
S
E
A
S
F
S
D
V
H
L
E
E
G
Site 39
S525
V
H
L
E
E
G
E
S
N
S
L
T
K
S
G
Site 40
S527
L
E
E
G
E
S
N
S
L
T
K
S
G
S
T
Site 41
T529
E
G
E
S
N
S
L
T
K
S
G
S
T
E
S
Site 42
S531
E
S
N
S
L
T
K
S
G
S
T
E
S
L
N
Site 43
S533
N
S
L
T
K
S
G
S
T
E
S
L
N
P
R
Site 44
T534
S
L
T
K
S
G
S
T
E
S
L
N
P
R
P
Site 45
S536
T
K
S
G
S
T
E
S
L
N
P
R
P
Q
T
Site 46
T543
S
L
N
P
R
P
Q
T
T
I
S
P
A
D
L
Site 47
T544
L
N
P
R
P
Q
T
T
I
S
P
A
D
L
H
Site 48
S546
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Site 49
Y555
A
D
L
H
G
M
W
Y
P
T
V
R
R
T
L
Site 50
T557
L
H
G
M
W
Y
P
T
V
R
R
T
L
V
C
Site 51
S596
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Site 52
S598
S
L
L
G
A
S
E
S
I
S
K
N
K
T
Q
Site 53
S600
L
G
A
S
E
S
I
S
K
N
K
T
Q
I
D
Site 54
T604
E
S
I
S
K
N
K
T
Q
I
D
G
Q
L
F
Site 55
S663
P
R
F
F
R
L
N
S
N
N
A
L
I
E
F
Site 56
T675
I
E
F
L
L
E
G
T
P
E
I
R
E
H
Y
Site 57
Y682
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Site 58
S685
I
R
E
H
Y
L
D
S
K
K
D
V
D
R
H
Site 59
S695
D
V
D
R
H
L
K
S
A
C
E
Q
F
I
Q
Site 60
T717
E
Q
L
E
E
F
M
T
K
V
S
A
L
K
T
Site 61
T724
T
K
V
S
A
L
K
T
M
A
S
Q
G
G
P
Site 62
S727
S
A
L
K
T
M
A
S
Q
G
G
P
K
Y
T
Site 63
Y733
A
S
Q
G
G
P
K
Y
T
L
S
Q
Q
P
W
Site 64
T734
S
Q
G
G
P
K
Y
T
L
S
Q
Q
P
W
A
Site 65
S736
G
G
P
K
Y
T
L
S
Q
Q
P
W
A
Q
P
Site 66
T759
T
A
Y
K
T
I
K
T
K
L
P
V
T
L
R
Site 67
S769
P
V
T
L
R
S
M
S
L
Y
L
S
N
K
D
Site 68
Y771
T
L
R
S
M
S
L
Y
L
S
N
K
D
T
E
Site 69
S773
R
S
M
S
L
Y
L
S
N
K
D
T
E
F
I
Site 70
T777
L
Y
L
S
N
K
D
T
E
F
I
L
F
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation