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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCC11
Full Name:
ATP-binding cassette sub-family C member 11
Alias:
Multidrug resistance-associated protein 8
Type:
Mass (Da):
154301
Number AA:
1382
UniProt ID:
Q96J66
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
R
T
Y
W
V
P
N
S
S
G
G
L
V
N
R
Site 2
Y33
D
M
V
S
G
L
I
Y
K
T
Y
T
L
Q
D
Site 3
Y36
S
G
L
I
Y
K
T
Y
T
L
Q
D
G
P
W
Site 4
T37
G
L
I
Y
K
T
Y
T
L
Q
D
G
P
W
S
Site 5
S44
T
L
Q
D
G
P
W
S
Q
Q
E
R
N
P
E
Site 6
Y64
A
V
P
P
W
G
K
Y
D
A
A
L
R
T
M
Site 7
T70
K
Y
D
A
A
L
R
T
M
I
P
F
R
P
K
Site 8
S107
L
T
P
L
M
I
Q
S
L
R
S
R
L
D
E
Site 9
T116
R
S
R
L
D
E
N
T
I
P
P
L
S
V
H
Site 10
S121
E
N
T
I
P
P
L
S
V
H
D
A
S
D
K
Site 11
S142
R
L
W
E
E
E
V
S
R
R
G
I
E
K
A
Site 12
S223
K
S
L
S
F
S
S
S
W
I
I
N
Q
R
T
Site 13
T342
S
D
Q
R
I
R
V
T
S
E
V
L
T
C
I
Site 14
S343
D
Q
R
I
R
V
T
S
E
V
L
T
C
I
K
Site 15
Y355
C
I
K
L
I
K
M
Y
T
W
E
K
P
F
A
Site 16
T356
I
K
L
I
K
M
Y
T
W
E
K
P
F
A
K
Site 17
T413
T
S
L
K
L
K
L
T
A
S
M
A
F
S
M
Site 18
S423
M
A
F
S
M
L
A
S
L
N
L
L
R
L
S
Site 19
S444
A
V
K
G
L
T
N
S
K
S
A
V
M
R
F
Site 20
S446
K
G
L
T
N
S
K
S
A
V
M
R
F
K
K
Site 21
S459
K
K
F
F
L
Q
E
S
P
V
F
Y
V
Q
T
Site 22
Y463
L
Q
E
S
P
V
F
Y
V
Q
T
L
Q
D
P
Site 23
T486
A
T
L
S
W
Q
Q
T
C
P
G
I
V
N
G
Site 24
S504
L
E
R
N
G
H
A
S
E
G
M
T
R
P
R
Site 25
S522
G
P
E
E
E
G
N
S
L
G
P
E
L
H
K
Site 26
S548
G
V
C
G
N
T
G
S
G
K
S
S
L
L
S
Site 27
S552
N
T
G
S
G
K
S
S
L
L
S
A
I
L
E
Site 28
S555
S
G
K
S
S
L
L
S
A
I
L
E
E
M
H
Site 29
S573
G
S
V
G
V
Q
G
S
L
A
Y
V
P
Q
Q
Site 30
Y603
G
A
Y
D
K
A
R
Y
L
Q
V
L
H
C
C
Site 31
S635
G
E
R
G
L
N
L
S
G
G
Q
K
Q
R
I
Site 32
S643
G
G
Q
K
Q
R
I
S
L
A
R
A
V
Y
S
Site 33
Y655
V
Y
S
D
R
Q
I
Y
L
L
D
D
P
L
S
Site 34
T680
F
E
E
C
I
K
K
T
L
R
G
K
T
V
V
Site 35
T685
K
K
T
L
R
G
K
T
V
V
L
V
T
H
Q
Site 36
Y726
L
M
Q
K
K
G
K
Y
A
Q
L
I
Q
K
M
Site 37
S762
E
S
Q
A
L
A
T
S
L
E
E
S
L
N
G
Site 38
S766
L
A
T
S
L
E
E
S
L
N
G
N
A
V
P
Site 39
T778
A
V
P
E
H
Q
L
T
Q
E
E
E
M
E
E
Site 40
S787
E
E
E
M
E
E
G
S
L
S
W
R
V
Y
H
Site 41
Y793
G
S
L
S
W
R
V
Y
H
H
Y
I
Q
A
A
Site 42
Y796
S
W
R
V
Y
H
H
Y
I
Q
A
A
G
G
Y
Site 43
S835
S
Y
W
L
E
Q
G
S
G
T
N
S
S
R
E
Site 44
S839
E
Q
G
S
G
T
N
S
S
R
E
S
N
G
T
Site 45
S840
Q
G
S
G
T
N
S
S
R
E
S
N
G
T
M
Site 46
S843
G
T
N
S
S
R
E
S
N
G
T
M
A
D
L
Site 47
T846
S
S
R
E
S
N
G
T
M
A
D
L
G
N
I
Site 48
Y862
D
N
P
Q
L
S
F
Y
Q
L
V
Y
G
L
N
Site 49
S892
T
K
V
T
R
K
A
S
T
A
L
H
N
K
L
Site 50
Y993
V
F
K
R
L
E
N
Y
S
R
S
P
L
F
S
Site 51
S994
F
K
R
L
E
N
Y
S
R
S
P
L
F
S
H
Site 52
S996
R
L
E
N
Y
S
R
S
P
L
F
S
H
I
L
Site 53
S1000
Y
S
R
S
P
L
F
S
H
I
L
N
S
L
Q
Site 54
S1011
N
S
L
Q
G
L
S
S
I
H
V
Y
G
K
T
Site 55
Y1015
G
L
S
S
I
H
V
Y
G
K
T
E
D
F
I
Site 56
T1018
S
I
H
V
Y
G
K
T
E
D
F
I
S
Q
F
Site 57
S1023
G
K
T
E
D
F
I
S
Q
F
K
R
L
T
D
Site 58
T1029
I
S
Q
F
K
R
L
T
D
A
Q
N
N
Y
L
Site 59
T1106
L
E
T
E
A
Q
F
T
A
V
E
R
I
L
Q
Site 60
Y1146
G
E
I
I
F
Q
D
Y
H
M
K
Y
R
D
N
Site 61
Y1150
F
Q
D
Y
H
M
K
Y
R
D
N
T
P
T
V
Site 62
T1154
H
M
K
Y
R
D
N
T
P
T
V
L
H
G
I
Site 63
T1156
K
Y
R
D
N
T
P
T
V
L
H
G
I
N
L
Site 64
T1177
V
V
G
I
V
G
R
T
G
S
G
K
S
S
L
Site 65
S1179
G
I
V
G
R
T
G
S
G
K
S
S
L
G
M
Site 66
S1182
G
R
T
G
S
G
K
S
S
L
G
M
A
L
F
Site 67
S1183
R
T
G
S
G
K
S
S
L
G
M
A
L
F
R
Site 68
S1216
I
G
L
E
D
L
R
S
K
L
S
V
I
P
Q
Site 69
S1219
E
D
L
R
S
K
L
S
V
I
P
Q
D
P
V
Site 70
T1254
I
W
D
A
L
E
R
T
F
L
T
K
A
I
S
Site 71
T1257
A
L
E
R
T
F
L
T
K
A
I
S
K
F
P
Site 72
S1261
T
F
L
T
K
A
I
S
K
F
P
K
K
L
H
Site 73
T1269
K
F
P
K
K
L
H
T
D
V
V
E
N
G
G
Site 74
S1279
V
E
N
G
G
N
F
S
V
G
E
R
Q
L
L
Site 75
S1307
L
I
D
E
A
T
A
S
I
D
M
E
T
D
T
Site 76
T1312
T
A
S
I
D
M
E
T
D
T
L
I
Q
R
T
Site 77
T1314
S
I
D
M
E
T
D
T
L
I
Q
R
T
I
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation