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Updated November 2019
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Protein Info
Short Name:
FAM46A
Full Name:
Protein FAM46A
Alias:
HBV X-transactivated gene 11 protein;HBV XAg-transactivated protein 11
Type:
Mass (Da):
49666
Number AA:
442
UniProt ID:
Q96IP4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
A
E
G
E
G
Y
F
A
M
S
E
D
E
Site 2
S11
G
E
G
Y
F
A
M
S
E
D
E
L
A
C
S
Site 3
S18
S
E
D
E
L
A
C
S
P
Y
I
P
L
G
G
Site 4
S47
G
D
F
G
G
G
G
S
F
G
G
H
C
L
D
Site 5
Y55
F
G
G
H
C
L
D
Y
C
E
S
P
T
A
H
Site 6
S79
Q
R
L
D
G
I
L
S
E
T
I
P
I
H
G
Site 7
T92
H
G
R
G
N
F
P
T
L
E
L
Q
P
S
L
Site 8
S133
S
H
V
L
H
Q
D
S
G
L
G
Y
K
D
L
Site 9
Y137
H
Q
D
S
G
L
G
Y
K
D
L
D
L
I
F
Site 10
T156
R
G
E
G
E
F
Q
T
V
K
D
V
V
L
D
Site 11
T179
G
V
N
K
E
K
I
T
P
L
T
L
K
E
A
Site 12
T182
K
E
K
I
T
P
L
T
L
K
E
A
Y
V
Q
Site 13
S202
C
N
D
S
D
R
W
S
L
I
S
L
S
N
N
Site 14
S205
S
D
R
W
S
L
I
S
L
S
N
N
S
G
K
Site 15
S207
R
W
S
L
I
S
L
S
N
N
S
G
K
N
V
Site 16
S221
V
E
L
K
F
V
D
S
L
R
R
Q
F
E
F
Site 17
S229
L
R
R
Q
F
E
F
S
V
D
S
F
Q
I
K
Site 18
S232
Q
F
E
F
S
V
D
S
F
Q
I
K
L
D
S
Site 19
S247
L
L
L
F
Y
E
C
S
E
N
P
M
T
E
T
Site 20
T252
E
C
S
E
N
P
M
T
E
T
F
H
P
T
I
Site 21
T254
S
E
N
P
M
T
E
T
F
H
P
T
I
I
G
Site 22
T282
L
C
N
K
I
I
A
T
R
N
P
E
E
I
R
Site 23
S308
V
R
G
F
R
P
A
S
D
E
I
K
T
L
Q
Site 24
T313
P
A
S
D
E
I
K
T
L
Q
R
Y
M
C
S
Site 25
Y317
E
I
K
T
L
Q
R
Y
M
C
S
R
F
F
I
Site 26
S327
S
R
F
F
I
D
F
S
D
I
G
E
Q
Q
R
Site 27
Y339
Q
Q
R
K
L
E
S
Y
L
Q
N
H
F
V
G
Site 28
Y352
V
G
L
E
D
R
K
Y
E
Y
L
M
T
L
H
Site 29
Y354
L
E
D
R
K
Y
E
Y
L
M
T
L
H
G
V
Site 30
T357
R
K
Y
E
Y
L
M
T
L
H
G
V
V
N
E
Site 31
T377
M
G
H
E
R
R
Q
T
L
N
L
I
T
M
L
Site 32
Y404
N
V
A
N
V
T
C
Y
Y
Q
P
A
P
Y
V
Site 33
Y410
C
Y
Y
Q
P
A
P
Y
V
A
D
A
N
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation