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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SGSM3
Full Name:
Small G protein signaling modulator 3
Alias:
DJ1042K10.2; MAP; Merlin-associated protein; RabGAPLP; Rab-GTPase-activating protein-like protein; RUN and SH3 containing 3; RUN and TBC1 domain-containing 3; RUSC3; RUTBC3
Type:
G protein regulator, misc.
Mass (Da):
85354
Number AA:
749
UniProt ID:
Q96HU1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005097
GO:0017137
PhosphoSite+
KinaseNET
Biological Process:
GO:0032486
GO:0007050
GO:0032313
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
G
S
H
T
P
A
C
G
P
F
S
Site 2
T16
C
G
P
F
S
A
L
T
P
S
I
W
P
Q
E
Site 3
Y28
P
Q
E
I
L
A
K
Y
T
Q
K
E
E
S
A
Site 4
Y41
S
A
E
Q
P
E
F
Y
Y
D
E
F
G
F
R
Site 5
Y42
A
E
Q
P
E
F
Y
Y
D
E
F
G
F
R
V
Site 6
Y50
D
E
F
G
F
R
V
Y
K
E
E
G
D
E
P
Site 7
S60
E
G
D
E
P
G
S
S
L
L
A
N
S
P
L
Site 8
S65
G
S
S
L
L
A
N
S
P
L
M
E
D
A
P
Site 9
T93
N
H
D
V
G
D
L
T
W
D
K
I
A
V
S
Site 10
S100
T
W
D
K
I
A
V
S
L
P
R
S
E
K
L
Site 11
S109
P
R
S
E
K
L
R
S
L
V
L
A
G
I
P
Site 12
S128
P
Q
L
W
M
R
L
S
G
A
L
Q
K
K
R
Site 13
S137
A
L
Q
K
K
R
N
S
E
L
S
Y
R
E
I
Site 14
S140
K
K
R
N
S
E
L
S
Y
R
E
I
V
K
N
Site 15
Y141
K
R
N
S
E
L
S
Y
R
E
I
V
K
N
S
Site 16
S149
R
E
I
V
K
N
S
S
N
D
E
T
I
A
A
Site 17
T153
K
N
S
S
N
D
E
T
I
A
A
K
Q
I
E
Site 18
T246
T
T
L
L
G
V
Q
T
D
Q
R
V
L
R
H
Site 19
S327
K
E
E
E
L
I
Q
S
E
N
S
A
S
I
F
Site 20
S332
I
Q
S
E
N
S
A
S
I
F
N
T
L
S
D
Site 21
T336
N
S
A
S
I
F
N
T
L
S
D
I
P
S
Q
Site 22
S338
A
S
I
F
N
T
L
S
D
I
P
S
Q
M
E
Site 23
S342
N
T
L
S
D
I
P
S
Q
M
E
D
A
E
L
Site 24
T368
L
T
D
V
A
V
E
T
Q
R
R
K
H
L
A
Site 25
Y376
Q
R
R
K
H
L
A
Y
L
I
A
D
Q
G
Q
Site 26
S394
A
G
T
L
T
N
L
S
Q
V
V
R
R
R
T
Site 27
T401
S
Q
V
V
R
R
R
T
Q
R
R
K
S
T
I
Site 28
S406
R
R
T
Q
R
R
K
S
T
I
T
A
L
L
F
Site 29
T407
R
T
Q
R
R
K
S
T
I
T
A
L
L
F
G
Site 30
T409
Q
R
R
K
S
T
I
T
A
L
L
F
G
E
D
Site 31
S455
C
T
D
P
K
N
C
S
V
E
L
T
P
D
Y
Site 32
T459
K
N
C
S
V
E
L
T
P
D
Y
S
M
E
S
Site 33
Y462
S
V
E
L
T
P
D
Y
S
M
E
S
H
Q
R
Site 34
S463
V
E
L
T
P
D
Y
S
M
E
S
H
Q
R
D
Site 35
Y474
H
Q
R
D
H
E
N
Y
V
A
C
S
R
S
H
Site 36
S480
N
Y
V
A
C
S
R
S
H
R
R
R
A
K
A
Site 37
S541
V
E
V
L
D
E
R
S
K
E
Y
S
I
A
G
Site 38
S545
D
E
R
S
K
E
Y
S
I
A
G
D
D
S
V
Site 39
S551
Y
S
I
A
G
D
D
S
V
T
E
G
V
T
D
Site 40
S580
E
H
G
L
K
K
P
S
L
L
G
G
A
C
H
Site 41
Y608
E
R
D
F
A
S
V
Y
S
R
L
V
L
C
K
Site 42
T616
S
R
L
V
L
C
K
T
F
R
L
D
E
D
G
Site 43
T627
D
E
D
G
K
V
L
T
P
E
E
L
L
Y
R
Site 44
Y633
L
T
P
E
E
L
L
Y
R
A
V
Q
S
V
N
Site 45
T642
A
V
Q
S
V
N
V
T
H
D
A
V
H
A
Q
Site 46
T680
V
L
C
S
S
L
P
T
V
E
K
W
Y
Q
P
Site 47
Y685
L
P
T
V
E
K
W
Y
Q
P
W
S
F
L
R
Site 48
S693
Q
P
W
S
F
L
R
S
P
G
W
V
Q
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation