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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AHCYL2
Full Name:
Putative adenosylhomocysteinase 3
Alias:
Adenosylhomocysteinase 3; AdoHcyase 3; EC 3.3.1.1; Long-IRBIT; S-adenosyl-L-homocysteine hydrolase 3; SAHH3
Type:
Phosphoprotein
Mass (Da):
66721
Number AA:
611
UniProt ID:
Q96HN2
International Prot ID:
IPI00101645
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004013
GO:0005488
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006730
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
V
Q
V
V
S
A
A
Site 2
S23
E
V
E
L
K
D
L
S
P
S
E
A
E
S
Q
Site 3
S25
E
L
K
D
L
S
P
S
E
A
E
S
Q
L
G
Site 4
S29
L
S
P
S
E
A
E
S
Q
L
G
L
S
T
A
Site 5
S89
Q
A
S
A
M
K
R
S
D
P
H
H
Q
H
Q
Site 6
S107
D
G
G
E
A
L
V
S
P
D
G
T
V
T
E
Site 7
T111
A
L
V
S
P
D
G
T
V
T
E
A
P
R
T
Site 8
T113
V
S
P
D
G
T
V
T
E
A
P
R
T
V
K
Site 9
T118
T
V
T
E
A
P
R
T
V
K
K
Q
I
Q
F
Site 10
T137
Q
E
F
N
K
R
P
T
K
I
G
R
R
S
L
Site 11
S143
P
T
K
I
G
R
R
S
L
S
R
S
I
S
Q
Site 12
S145
K
I
G
R
R
S
L
S
R
S
I
S
Q
S
S
Site 13
S147
G
R
R
S
L
S
R
S
I
S
Q
S
S
T
D
Site 14
S149
R
S
L
S
R
S
I
S
Q
S
S
T
D
S
Y
Site 15
S151
L
S
R
S
I
S
Q
S
S
T
D
S
Y
S
S
Site 16
S152
S
R
S
I
S
Q
S
S
T
D
S
Y
S
S
A
Site 17
T153
R
S
I
S
Q
S
S
T
D
S
Y
S
S
A
A
Site 18
S155
I
S
Q
S
S
T
D
S
Y
S
S
A
A
S
Y
Site 19
Y156
S
Q
S
S
T
D
S
Y
S
S
A
A
S
Y
T
Site 20
S157
Q
S
S
T
D
S
Y
S
S
A
A
S
Y
T
D
Site 21
S158
S
S
T
D
S
Y
S
S
A
A
S
Y
T
D
S
Site 22
S161
D
S
Y
S
S
A
A
S
Y
T
D
S
S
D
D
Site 23
Y162
S
Y
S
S
A
A
S
Y
T
D
S
S
D
D
E
Site 24
T163
Y
S
S
A
A
S
Y
T
D
S
S
D
D
E
T
Site 25
S165
S
A
A
S
Y
T
D
S
S
D
D
E
T
S
P
Site 26
S166
A
A
S
Y
T
D
S
S
D
D
E
T
S
P
R
Site 27
T170
T
D
S
S
D
D
E
T
S
P
R
D
K
Q
Q
Site 28
S171
D
S
S
D
D
E
T
S
P
R
D
K
Q
Q
K
Site 29
S180
R
D
K
Q
Q
K
N
S
K
G
S
S
D
F
C
Site 30
S184
Q
K
N
S
K
G
S
S
D
F
C
V
K
N
I
Site 31
Y319
G
D
L
T
H
W
I
Y
K
K
Y
P
N
M
F
Site 32
Y322
T
H
W
I
Y
K
K
Y
P
N
M
F
K
K
I
Site 33
T338
G
I
V
E
E
S
V
T
G
V
H
R
L
Y
Q
Site 34
Y344
V
T
G
V
H
R
L
Y
Q
L
S
K
A
G
K
Site 35
S362
P
A
M
N
V
N
D
S
V
T
K
Q
K
F
D
Site 36
T364
M
N
V
N
D
S
V
T
K
Q
K
F
D
N
L
Site 37
Y372
K
Q
K
F
D
N
L
Y
C
C
R
E
S
I
L
Site 38
S377
N
L
Y
C
C
R
E
S
I
L
D
G
L
K
R
Site 39
T386
L
D
G
L
K
R
T
T
D
M
M
F
G
G
K
Site 40
T483
C
N
M
G
H
S
N
T
E
I
D
V
A
S
L
Site 41
S489
N
T
E
I
D
V
A
S
L
R
T
P
E
L
T
Site 42
T492
I
D
V
A
S
L
R
T
P
E
L
T
W
E
R
Site 43
T496
S
L
R
T
P
E
L
T
W
E
R
V
R
S
Q
Site 44
Y563
G
R
Y
K
Q
D
V
Y
L
L
P
K
K
M
D
Site 45
Y572
L
P
K
K
M
D
E
Y
V
A
S
L
H
L
P
Site 46
S575
K
M
D
E
Y
V
A
S
L
H
L
P
T
F
D
Site 47
Y595
L
T
D
E
Q
A
K
Y
L
G
L
N
K
N
G
Site 48
Y608
N
G
P
F
K
P
N
Y
Y
R
Y
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation