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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
F25965
Full Name:
Protein lin-37 homolog
Alias:
LIN37; Lin-37; ZK418.4
Type:
Mass (Da):
28383
Number AA:
246
UniProt ID:
Q96GY3
International Prot ID:
IPI00062869
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
K
V
K
V
E
K
S
E
L
E
M
A
K
A
Site 2
S33
L
Q
C
L
L
E
K
S
H
M
D
R
E
R
L
Site 3
T47
L
D
E
E
A
G
K
T
P
S
D
T
H
N
K
Site 4
S49
E
E
A
G
K
T
P
S
D
T
H
N
K
D
C
Site 5
T51
A
G
K
T
P
S
D
T
H
N
K
D
C
S
I
Site 6
T61
K
D
C
S
I
A
A
T
G
K
R
P
S
A
R
Site 7
S66
A
A
T
G
K
R
P
S
A
R
F
P
H
Q
R
Site 8
S92
A
E
G
G
P
Q
R
S
N
T
Y
V
I
K
L
Site 9
T94
G
G
P
Q
R
S
N
T
Y
V
I
K
L
F
D
Site 10
Y95
G
P
Q
R
S
N
T
Y
V
I
K
L
F
D
R
Site 11
S110
S
V
D
L
A
Q
F
S
E
N
T
P
L
Y
P
Site 12
T113
L
A
Q
F
S
E
N
T
P
L
Y
P
I
C
R
Site 13
S126
C
R
A
W
M
R
N
S
P
S
V
R
E
R
E
Site 14
S128
A
W
M
R
N
S
P
S
V
R
E
R
E
C
S
Site 15
S135
S
V
R
E
R
E
C
S
P
S
S
P
L
P
P
Site 16
S137
R
E
R
E
C
S
P
S
S
P
L
P
P
L
P
Site 17
S138
E
R
E
C
S
P
S
S
P
L
P
P
L
P
E
Site 18
S150
L
P
E
D
E
E
G
S
E
V
T
N
S
K
S
Site 19
T153
D
E
E
G
S
E
V
T
N
S
K
S
R
D
V
Site 20
S155
E
G
S
E
V
T
N
S
K
S
R
D
V
Y
K
Site 21
S157
S
E
V
T
N
S
K
S
R
D
V
Y
K
L
P
Site 22
Y161
N
S
K
S
R
D
V
Y
K
L
P
P
P
T
P
Site 23
T167
V
Y
K
L
P
P
P
T
P
P
G
P
P
G
D
Site 24
S178
P
P
G
D
A
C
R
S
R
I
P
S
P
L
Q
Site 25
S182
A
C
R
S
R
I
P
S
P
L
Q
P
E
M
Q
Site 26
T191
L
Q
P
E
M
Q
G
T
P
D
D
E
P
S
E
Site 27
S197
G
T
P
D
D
E
P
S
E
P
E
P
S
P
S
Site 28
S202
E
P
S
E
P
E
P
S
P
S
T
L
I
Y
R
Site 29
S204
S
E
P
E
P
S
P
S
T
L
I
Y
R
N
M
Site 30
T205
E
P
E
P
S
P
S
T
L
I
Y
R
N
M
Q
Site 31
Y208
P
S
P
S
T
L
I
Y
R
N
M
Q
R
W
K
Site 32
S225
R
Q
R
W
K
E
A
S
H
R
N
Q
L
R
Y
Site 33
Y232
S
H
R
N
Q
L
R
Y
S
E
S
M
K
I
L
Site 34
S233
H
R
N
Q
L
R
Y
S
E
S
M
K
I
L
R
Site 35
S235
N
Q
L
R
Y
S
E
S
M
K
I
L
R
E
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation