KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
APIP
Full Name:
Probable methylthioribulose-1-phosphate dehydratase
Alias:
APAF1 interacting protein; APIP2; CGI-29; CGI-29 protein; Likely ortholog of mouse monocyte macrophage 19; MMRP19
Type:
Amino Acid Metabolism - cysteine and methionine; Apoptosis
Mass (Da):
27125
Number AA:
242
UniProt ID:
Q96GX9
International Prot ID:
IPI00549730
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008219
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
Q
D
K
E
H
P
R
Y
L
I
P
E
L
C
K
Site 2
Y36
P
E
L
C
K
Q
F
Y
H
L
G
W
V
T
G
Site 3
S49
T
G
T
G
G
G
I
S
L
K
H
G
D
E
I
Site 4
Y57
L
K
H
G
D
E
I
Y
I
A
P
S
G
V
Q
Site 5
S84
D
I
N
E
K
D
I
S
G
P
S
P
S
K
K
Site 6
S87
E
K
D
I
S
G
P
S
P
S
K
K
L
K
K
Site 7
S89
D
I
S
G
P
S
P
S
K
K
L
K
K
S
Q
Site 8
S95
P
S
K
K
L
K
K
S
Q
C
T
P
L
F
M
Site 9
T98
K
L
K
K
S
Q
C
T
P
L
F
M
N
A
Y
Site 10
T136
P
G
R
E
F
K
I
T
H
Q
E
M
I
K
G
Site 11
Y152
K
K
C
T
S
G
G
Y
Y
R
Y
D
D
M
L
Site 12
Y153
K
C
T
S
G
G
Y
Y
R
Y
D
D
M
L
V
Site 13
T167
V
V
P
I
I
E
N
T
P
E
E
K
D
L
K
Site 14
S187
A
M
N
E
Y
P
D
S
C
A
V
L
V
R
R
Site 15
Y198
L
V
R
R
H
G
V
Y
V
W
G
E
T
W
E
Site 16
T209
E
T
W
E
K
A
K
T
M
C
E
C
Y
D
Y
Site 17
S223
Y
L
F
D
I
A
V
S
M
K
K
V
G
L
D
Site 18
S232
K
K
V
G
L
D
P
S
Q
L
P
V
G
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation