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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MARS2
Full Name:
Methionyl-tRNA synthetase, mitochondrial
Alias:
Methionine--tRNA ligase 2;Mitochondrial methionine--tRNA ligase
Type:
Mass (Da):
66591
Number AA:
593
UniProt ID:
Q96GW9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
R
T
G
A
S
R
L
S
L
L
E
D
F
G
P
Site 2
Y28
L
E
D
F
G
P
R
Y
Y
S
S
G
S
L
S
Site 3
Y29
E
D
F
G
P
R
Y
Y
S
S
G
S
L
S
A
Site 4
S30
D
F
G
P
R
Y
Y
S
S
G
S
L
S
A
G
Site 5
S31
F
G
P
R
Y
Y
S
S
G
S
L
S
A
G
D
Site 6
S33
P
R
Y
Y
S
S
G
S
L
S
A
G
D
D
A
Site 7
S35
Y
Y
S
S
G
S
L
S
A
G
D
D
A
C
D
Site 8
S82
H
R
R
L
R
G
P
S
T
A
A
T
R
F
S
Site 9
T83
R
R
L
R
G
P
S
T
A
A
T
R
F
S
T
Site 10
T86
R
G
P
S
T
A
A
T
R
F
S
T
G
T
D
Site 11
S89
S
T
A
A
T
R
F
S
T
G
T
D
E
H
G
Site 12
T90
T
A
A
T
R
F
S
T
G
T
D
E
H
G
L
Site 13
T92
A
T
R
F
S
T
G
T
D
E
H
G
L
K
I
Site 14
S118
T
E
L
C
D
R
V
S
E
Q
F
Q
Q
L
F
Site 15
T139
C
T
D
F
I
R
T
T
E
A
R
H
R
V
A
Site 16
S156
H
F
W
G
V
L
K
S
R
G
L
L
Y
K
G
Site 17
Y161
L
K
S
R
G
L
L
Y
K
G
V
Y
E
G
W
Site 18
Y169
K
G
V
Y
E
G
W
Y
C
A
S
D
E
C
F
Site 19
T183
F
L
P
E
A
K
V
T
Q
Q
P
G
P
S
G
Site 20
S189
V
T
Q
Q
P
G
P
S
G
D
S
F
P
V
S
Site 21
S192
Q
P
G
P
S
G
D
S
F
P
V
S
L
E
S
Site 22
S196
S
G
D
S
F
P
V
S
L
E
S
G
H
P
V
Site 23
S199
S
F
P
V
S
L
E
S
G
H
P
V
S
W
T
Site 24
S204
L
E
S
G
H
P
V
S
W
T
K
E
E
N
Y
Site 25
T206
S
G
H
P
V
S
W
T
K
E
E
N
Y
I
F
Site 26
Y211
S
W
T
K
E
E
N
Y
I
F
R
L
S
Q
F
Site 27
S216
E
N
Y
I
F
R
L
S
Q
F
R
K
P
L
Q
Site 28
T234
R
G
N
P
Q
A
I
T
P
E
P
F
H
H
V
Site 29
S254
D
E
E
L
P
D
L
S
V
S
R
R
S
S
H
Site 30
S256
E
L
P
D
L
S
V
S
R
R
S
S
H
L
H
Site 31
S259
D
L
S
V
S
R
R
S
S
H
L
H
W
G
I
Site 32
S260
L
S
V
S
R
R
S
S
H
L
H
W
G
I
P
Site 33
T275
V
P
G
D
D
S
Q
T
I
Y
V
W
L
D
A
Site 34
Y292
N
Y
L
T
V
I
G
Y
P
N
A
E
F
K
S
Site 35
S351
C
G
Q
K
M
S
K
S
L
G
N
V
V
D
P
Site 36
T360
G
N
V
V
D
P
R
T
C
L
N
R
Y
T
V
Site 37
Y365
P
R
T
C
L
N
R
Y
T
V
D
G
F
R
Y
Site 38
Y386
V
P
N
W
D
C
D
Y
Y
D
E
K
V
V
K
Site 39
Y387
P
N
W
D
C
D
Y
Y
D
E
K
V
V
K
L
Site 40
T411
G
G
L
L
N
R
C
T
A
K
R
I
N
P
S
Site 41
Y421
R
I
N
P
S
E
T
Y
P
A
F
C
T
T
C
Site 42
S439
E
P
G
L
V
G
P
S
V
R
A
Q
A
E
D
Site 43
Y464
P
K
Q
V
A
D
H
Y
D
N
F
R
I
Y
K
Site 44
Y470
H
Y
D
N
F
R
I
Y
K
A
L
E
A
V
S
Site 45
S478
K
A
L
E
A
V
S
S
C
V
R
Q
T
N
G
Site 46
T483
V
S
S
C
V
R
Q
T
N
G
F
V
Q
R
H
Site 47
S544
S
R
L
G
V
S
A
S
E
R
S
L
G
E
L
Site 48
Y552
E
R
S
L
G
E
L
Y
F
L
P
R
F
Y
G
Site 49
Y558
L
Y
F
L
P
R
F
Y
G
H
P
C
P
F
E
Site 50
T573
G
R
R
L
G
P
E
T
G
L
L
F
P
R
L
Site 51
S583
L
F
P
R
L
D
Q
S
R
T
W
L
V
K
A
Site 52
T585
P
R
L
D
Q
S
R
T
W
L
V
K
A
H
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation