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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BCAN
Full Name:
Brevican core protein
Alias:
Brain-enriched hyaluronan-binding protein; PGCB; Protein BEHAB
Type:
Mass (Da):
99118
Number AA:
911
UniProt ID:
Q96GW7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005578
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005540
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
D
V
L
E
G
D
S
S
E
D
R
A
F
R
V
Site 2
Y61
T
I
P
C
H
V
H
Y
L
R
P
P
P
S
R
Site 3
S67
H
Y
L
R
P
P
P
S
R
R
A
V
L
G
S
Site 4
S74
S
R
R
A
V
L
G
S
P
R
V
K
W
T
F
Site 5
T80
G
S
P
R
V
K
W
T
F
L
S
R
G
R
E
Site 6
S83
R
V
K
W
T
F
L
S
R
G
R
E
A
E
V
Site 7
S125
T
D
V
S
L
A
L
S
E
L
R
P
N
D
S
Site 8
S132
S
E
L
R
P
N
D
S
G
I
Y
R
C
E
V
Site 9
Y135
R
P
N
D
S
G
I
Y
R
C
E
V
Q
H
G
Site 10
S146
V
Q
H
G
I
D
D
S
S
D
A
V
E
V
K
Site 11
S147
Q
H
G
I
D
D
S
S
D
A
V
E
V
K
V
Site 12
Y161
V
K
G
V
V
F
L
Y
R
E
G
S
A
R
Y
Site 13
S171
G
S
A
R
Y
A
F
S
F
S
G
A
Q
E
A
Site 14
T212
A
G
W
L
S
D
Q
T
V
R
Y
P
I
Q
T
Site 15
Y215
L
S
D
Q
T
V
R
Y
P
I
Q
T
P
R
E
Site 16
T219
T
V
R
Y
P
I
Q
T
P
R
E
A
C
Y
G
Site 17
Y237
G
F
P
G
V
R
N
Y
G
V
V
D
P
D
D
Site 18
Y246
V
V
D
P
D
D
L
Y
D
V
Y
C
Y
A
E
Site 19
Y249
P
D
D
L
Y
D
V
Y
C
Y
A
E
D
L
N
Site 20
T269
G
D
P
P
E
K
L
T
L
E
E
A
R
A
Y
Site 21
Y276
T
L
E
E
A
R
A
Y
C
Q
E
R
G
A
E
Site 22
T287
R
G
A
E
I
A
T
T
G
Q
L
Y
A
A
W
Site 23
S302
D
G
G
L
D
H
C
S
P
G
W
L
A
D
G
Site 24
Y313
L
A
D
G
S
V
R
Y
P
I
V
T
P
S
Q
Site 25
T317
S
V
R
Y
P
I
V
T
P
S
Q
R
C
G
G
Site 26
S319
R
Y
P
I
V
T
P
S
Q
R
C
G
G
G
L
Site 27
T339
L
F
L
F
P
N
Q
T
G
F
P
N
K
H
S
Site 28
Y351
K
H
S
R
F
N
V
Y
C
F
R
D
S
A
Q
Site 29
S356
N
V
Y
C
F
R
D
S
A
Q
P
S
A
I
P
Site 30
S360
F
R
D
S
A
Q
P
S
A
I
P
E
A
S
N
Site 31
S366
P
S
A
I
P
E
A
S
N
P
A
S
N
P
A
Site 32
S370
P
E
A
S
N
P
A
S
N
P
A
S
D
G
L
Site 33
S374
N
P
A
S
N
P
A
S
D
G
L
E
A
I
V
Site 34
S399
L
P
Q
E
A
T
E
S
E
S
R
G
A
I
Y
Site 35
Y406
S
E
S
R
G
A
I
Y
S
I
P
I
M
E
D
Site 36
S407
E
S
R
G
A
I
Y
S
I
P
I
M
E
D
G
Site 37
S419
E
D
G
G
G
G
S
S
T
P
E
D
P
A
E
Site 38
T420
D
G
G
G
G
S
S
T
P
E
D
P
A
E
A
Site 39
T430
D
P
A
E
A
P
R
T
L
L
E
F
E
T
Q
Site 40
T436
R
T
L
L
E
F
E
T
Q
S
M
V
P
P
T
Site 41
Y459
A
L
E
E
E
E
K
Y
E
D
E
E
E
K
E
Site 42
S484
E
A
L
W
A
W
P
S
E
L
S
S
P
G
P
Site 43
S488
A
W
P
S
E
L
S
S
P
G
P
E
A
S
L
Site 44
S494
S
S
P
G
P
E
A
S
L
P
T
E
P
A
A
Site 45
S505
E
P
A
A
Q
E
E
S
L
S
Q
A
P
A
R
Site 46
S507
A
A
Q
E
E
S
L
S
Q
A
P
A
R
A
V
Site 47
S520
A
V
L
Q
P
G
A
S
P
L
P
D
G
E
S
Site 48
S527
S
P
L
P
D
G
E
S
E
A
S
R
P
P
R
Site 49
S530
P
D
G
E
S
E
A
S
R
P
P
R
V
H
G
Site 50
T540
P
R
V
H
G
P
P
T
E
T
L
P
T
P
R
Site 51
T545
P
P
T
E
T
L
P
T
P
R
E
R
N
L
A
Site 52
S553
P
R
E
R
N
L
A
S
P
S
P
S
T
L
V
Site 53
S555
E
R
N
L
A
S
P
S
P
S
T
L
V
E
A
Site 54
S557
N
L
A
S
P
S
P
S
T
L
V
E
A
R
E
Site 55
T569
A
R
E
V
G
E
A
T
G
G
P
E
L
S
G
Site 56
S575
A
T
G
G
P
E
L
S
G
V
P
R
G
E
S
Site 57
S582
S
G
V
P
R
G
E
S
E
E
T
G
S
S
E
Site 58
T585
P
R
G
E
S
E
E
T
G
S
S
E
G
A
P
Site 59
S587
G
E
S
E
E
T
G
S
S
E
G
A
P
S
L
Site 60
S588
E
S
E
E
T
G
S
S
E
G
A
P
S
L
L
Site 61
S593
G
S
S
E
G
A
P
S
L
L
P
A
T
R
A
Site 62
T598
A
P
S
L
L
P
A
T
R
A
P
E
G
T
R
Site 63
S611
T
R
E
L
E
A
P
S
E
D
N
S
G
R
T
Site 64
S615
E
A
P
S
E
D
N
S
G
R
T
A
P
A
G
Site 65
S624
R
T
A
P
A
G
T
S
V
Q
A
Q
P
V
L
Site 66
T633
Q
A
Q
P
V
L
P
T
D
S
A
S
R
G
G
Site 67
S635
Q
P
V
L
P
T
D
S
A
S
R
G
G
V
A
Site 68
S653
A
S
G
D
C
V
P
S
P
C
H
N
G
G
T
Site 69
Y700
D
A
F
Q
G
A
C
Y
K
H
F
S
T
R
R
Site 70
S708
K
H
F
S
T
R
R
S
W
E
E
A
E
T
Q
Site 71
T714
R
S
W
E
E
A
E
T
Q
C
R
M
Y
G
A
Site 72
Y719
A
E
T
Q
C
R
M
Y
G
A
H
L
A
S
I
Site 73
S727
G
A
H
L
A
S
I
S
T
P
E
E
Q
D
F
Site 74
T728
A
H
L
A
S
I
S
T
P
E
E
Q
D
F
I
Site 75
Y742
I
N
N
R
Y
R
E
Y
Q
W
I
G
L
N
D
Site 76
Y766
S
D
G
V
P
L
L
Y
E
N
W
N
P
G
Q
Site 77
S776
W
N
P
G
Q
P
D
S
Y
F
L
S
G
E
N
Site 78
Y777
N
P
G
Q
P
D
S
Y
F
L
S
G
E
N
C
Site 79
S780
Q
P
D
S
Y
F
L
S
G
E
N
C
V
V
M
Site 80
Y834
F
G
R
P
R
L
R
Y
E
V
D
T
V
L
R
Site 81
T838
R
L
R
Y
E
V
D
T
V
L
R
Y
R
C
R
Site 82
Y842
E
V
D
T
V
L
R
Y
R
C
R
E
G
L
A
Site 83
S870
R
W
E
A
P
Q
I
S
C
V
P
R
R
P
A
Site 84
S905
K
A
L
L
I
P
P
S
S
P
M
P
G
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation