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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC45
Full Name:
Coiled-coil domain-containing protein 45
Alias:
CCD45
Type:
Uncharacterized protein
Mass (Da):
95297
Number AA:
821
UniProt ID:
Q96GE4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S57
D
L
I
V
I
P
R
S
Q
E
D
D
A
H
N
Site 2
S82
D
Y
L
Q
V
S
L
S
H
I
T
G
E
N
I
Site 3
S96
I
V
K
G
D
K
E
S
I
K
N
L
L
E
I
Site 4
T112
D
G
L
L
E
Y
L
T
E
R
I
S
E
T
S
Site 5
S116
E
Y
L
T
E
R
I
S
E
T
S
H
E
K
S
Site 6
S119
T
E
R
I
S
E
T
S
H
E
K
S
E
T
E
Site 7
S123
S
E
T
S
H
E
K
S
E
T
E
Q
Y
F
K
Site 8
T125
T
S
H
E
K
S
E
T
E
Q
Y
F
K
E
S
Site 9
Y128
E
K
S
E
T
E
Q
Y
F
K
E
S
D
R
G
Site 10
S132
T
E
Q
Y
F
K
E
S
D
R
G
E
R
L
E
Site 11
S143
E
R
L
E
E
P
E
S
T
K
E
S
K
S
S
Site 12
T144
R
L
E
E
P
E
S
T
K
E
S
K
S
S
W
Site 13
S147
E
P
E
S
T
K
E
S
K
S
S
W
K
R
V
Site 14
S149
E
S
T
K
E
S
K
S
S
W
K
R
V
S
F
Site 15
S150
S
T
K
E
S
K
S
S
W
K
R
V
S
F
G
Site 16
S155
K
S
S
W
K
R
V
S
F
G
R
C
S
L
S
Site 17
S160
R
V
S
F
G
R
C
S
L
S
S
E
M
L
G
Site 18
S162
S
F
G
R
C
S
L
S
S
E
M
L
G
P
S
Site 19
S163
F
G
R
C
S
L
S
S
E
M
L
G
P
S
W
Site 20
S169
S
S
E
M
L
G
P
S
W
D
G
D
E
A
E
Site 21
T178
D
G
D
E
A
E
S
T
G
E
I
I
R
L
G
Site 22
T187
E
I
I
R
L
G
D
T
A
H
T
F
S
L
R
Site 23
T190
R
L
G
D
T
A
H
T
F
S
L
R
S
N
G
Site 24
S192
G
D
T
A
H
T
F
S
L
R
S
N
G
A
Q
Site 25
S206
Q
C
P
N
E
M
L
S
K
K
A
L
A
S
P
Site 26
S212
L
S
K
K
A
L
A
S
P
S
S
K
S
H
E
Site 27
S215
K
A
L
A
S
P
S
S
K
S
H
E
D
M
L
Site 28
S217
L
A
S
P
S
S
K
S
H
E
D
M
L
Y
P
Site 29
Y223
K
S
H
E
D
M
L
Y
P
P
S
V
L
S
K
Site 30
S226
E
D
M
L
Y
P
P
S
V
L
S
K
S
R
T
Site 31
S229
L
Y
P
P
S
V
L
S
K
S
R
T
S
F
V
Site 32
S231
P
P
S
V
L
S
K
S
R
T
S
F
V
E
D
Site 33
T233
S
V
L
S
K
S
R
T
S
F
V
E
D
T
E
Site 34
S234
V
L
S
K
S
R
T
S
F
V
E
D
T
E
T
Site 35
T239
R
T
S
F
V
E
D
T
E
T
L
S
V
S
G
Site 36
S243
V
E
D
T
E
T
L
S
V
S
G
I
P
N
A
Site 37
Y267
A
I
P
L
H
P
P
Y
H
P
S
E
P
R
A
Site 38
S270
L
H
P
P
Y
H
P
S
E
P
R
A
P
C
P
Site 39
Y282
P
C
P
I
G
K
E
Y
L
H
S
S
H
C
S
Site 40
S285
I
G
K
E
Y
L
H
S
S
H
C
S
P
A
V
Site 41
S286
G
K
E
Y
L
H
S
S
H
C
S
P
A
V
N
Site 42
S289
Y
L
H
S
S
H
C
S
P
A
V
N
S
T
G
Site 43
S302
T
G
E
H
T
E
F
S
G
D
L
D
D
G
L
Site 44
S313
D
D
G
L
F
L
I
S
K
L
P
K
G
S
K
Site 45
Y324
K
G
S
K
W
E
V
Y
P
A
Q
V
Q
G
P
Site 46
T333
A
Q
V
Q
G
P
R
T
R
K
P
P
K
G
K
Site 47
T347
K
R
N
E
N
R
A
T
A
S
S
C
N
S
P
Site 48
S349
N
E
N
R
A
T
A
S
S
C
N
S
P
F
P
Site 49
S350
E
N
R
A
T
A
S
S
C
N
S
P
F
P
Q
Site 50
S353
A
T
A
S
S
C
N
S
P
F
P
Q
R
P
R
Site 51
T364
Q
R
P
R
K
R
L
T
E
Q
E
L
H
D
V
Site 52
S372
E
Q
E
L
H
D
V
S
E
K
L
S
Q
R
L
Site 53
S376
H
D
V
S
E
K
L
S
Q
R
L
S
E
L
D
Site 54
S380
E
K
L
S
Q
R
L
S
E
L
D
W
M
L
K
Site 55
S388
E
L
D
W
M
L
K
S
A
L
G
D
R
I
K
Site 56
T398
G
D
R
I
K
E
K
T
D
H
K
E
E
N
T
Site 57
T414
N
E
E
V
E
D
G
T
E
E
T
L
S
Q
H
Site 58
S419
D
G
T
E
E
T
L
S
Q
H
S
D
G
I
V
Site 59
S422
E
E
T
L
S
Q
H
S
D
G
I
V
E
Y
G
Site 60
Y428
H
S
D
G
I
V
E
Y
G
P
K
K
S
R
P
Site 61
S433
V
E
Y
G
P
K
K
S
R
P
G
L
S
M
R
Site 62
S438
K
K
S
R
P
G
L
S
M
R
R
K
P
P
Y
Site 63
Y445
S
M
R
R
K
P
P
Y
R
S
H
S
L
S
P
Site 64
S447
R
R
K
P
P
Y
R
S
H
S
L
S
P
S
P
Site 65
S449
K
P
P
Y
R
S
H
S
L
S
P
S
P
V
N
Site 66
S451
P
Y
R
S
H
S
L
S
P
S
P
V
N
K
H
Site 67
S453
R
S
H
S
L
S
P
S
P
V
N
K
H
K
Q
Site 68
T474
R
Q
R
K
P
R
E
T
D
V
R
Q
F
Q
A
Site 69
T526
G
E
A
V
R
K
G
T
P
E
C
S
Q
P
W
Site 70
S530
R
K
G
T
P
E
C
S
Q
P
W
K
I
Y
S
Site 71
Y536
C
S
Q
P
W
K
I
Y
S
R
K
T
T
T
Q
Site 72
T540
W
K
I
Y
S
R
K
T
T
T
Q
S
L
R
G
Site 73
T541
K
I
Y
S
R
K
T
T
T
Q
S
L
R
G
G
Site 74
S544
S
R
K
T
T
T
Q
S
L
R
G
G
L
P
K
Site 75
T626
L
R
R
H
D
L
L
T
T
L
V
K
K
E
Y
Site 76
T627
R
R
H
D
L
L
T
T
L
V
K
K
E
Y
E
Site 77
Y633
T
T
L
V
K
K
E
Y
E
H
N
K
R
L
Q
Site 78
T652
C
I
R
R
Q
R
L
T
Q
S
K
I
K
E
N
Site 79
Y669
Q
I
V
R
A
R
K
Y
Y
D
D
Y
R
V
Q
Site 80
Y670
I
V
R
A
R
K
Y
Y
D
D
Y
R
V
Q
L
Site 81
Y673
A
R
K
Y
Y
D
D
Y
R
V
Q
L
C
A
K
Site 82
T686
A
K
M
M
R
M
R
T
R
E
E
M
I
F
K
Site 83
Y713
R
L
R
D
L
R
N
Y
A
K
E
K
R
D
E
Site 84
Y735
E
L
D
S
M
E
N
Y
Y
K
D
Q
F
S
L
Site 85
Y736
L
D
S
M
E
N
Y
Y
K
D
Q
F
S
L
L
Site 86
S741
N
Y
Y
K
D
Q
F
S
L
L
A
E
A
I
S
Site 87
S748
S
L
L
A
E
A
I
S
Q
E
H
Q
E
L
K
Site 88
S760
E
L
K
A
R
E
K
S
Q
A
Q
T
L
H
K
Site 89
T788
Q
Q
L
Q
D
M
I
T
Q
N
D
D
D
V
F
Site 90
S806
L
E
A
E
R
F
R
S
R
L
Q
L
A
S
F
Site 91
S812
R
S
R
L
Q
L
A
S
F
Q
Y
S
K
S
P
Site 92
S816
Q
L
A
S
F
Q
Y
S
K
S
P
S
L
_
_
Site 93
S818
A
S
F
Q
Y
S
K
S
P
S
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation