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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCMH1
Full Name:
Polycomb protein SCMH1
Alias:
polycomb protein scmh1; scmh1; scmh1 protein; scml3; sex comb on midleg 1; sex comb on midleg 1 isoform 1; sex comb on midleg 1 isoform 2
Type:
Mass (Da):
73354
Number AA:
660
UniProt ID:
Q96GD3
International Prot ID:
IPI00187110
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0009653
GO:0016458
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
G
S
P
L
G
H
F
T
W
D
K
Y
L
K
E
Site 2
Y33
G
H
F
T
W
D
K
Y
L
K
E
T
C
S
V
Site 3
S39
K
Y
L
K
E
T
C
S
V
P
A
P
V
H
C
Site 4
S50
P
V
H
C
F
K
Q
S
Y
T
P
P
S
N
E
Site 5
Y51
V
H
C
F
K
Q
S
Y
T
P
P
S
N
E
F
Site 6
T52
H
C
F
K
Q
S
Y
T
P
P
S
N
E
F
K
Site 7
S55
K
Q
S
Y
T
P
P
S
N
E
F
K
I
S
M
Site 8
S61
P
S
N
E
F
K
I
S
M
K
L
E
A
Q
D
Site 9
T72
E
A
Q
D
P
R
N
T
T
S
T
C
I
A
T
Site 10
T73
A
Q
D
P
R
N
T
T
S
T
C
I
A
T
V
Site 11
S74
Q
D
P
R
N
T
T
S
T
C
I
A
T
V
V
Site 12
T75
D
P
R
N
T
T
S
T
C
I
A
T
V
V
G
Site 13
T79
T
T
S
T
C
I
A
T
V
V
G
L
T
G
A
Site 14
T84
I
A
T
V
V
G
L
T
G
A
R
L
R
L
R
Site 15
S95
L
R
L
R
L
D
G
S
D
N
K
N
D
F
W
Site 16
S107
D
F
W
R
L
V
D
S
A
E
I
Q
P
I
G
Site 17
S161
I
F
H
K
E
P
P
S
P
S
H
N
F
F
K
Site 18
S163
H
K
E
P
P
S
P
S
H
N
F
F
K
M
G
Site 19
T200
R
G
S
E
V
L
V
T
F
D
G
W
R
G
A
Site 20
T228
P
V
G
W
C
S
L
T
G
D
N
L
Q
P
P
Site 21
T237
D
N
L
Q
P
P
G
T
K
V
V
I
P
K
N
Site 22
Y246
V
V
I
P
K
N
P
Y
P
A
S
D
V
N
T
Site 23
S249
P
K
N
P
Y
P
A
S
D
V
N
T
E
K
P
Site 24
T253
Y
P
A
S
D
V
N
T
E
K
P
S
I
H
S
Site 25
S257
D
V
N
T
E
K
P
S
I
H
S
S
T
K
T
Site 26
S261
E
K
P
S
I
H
S
S
T
K
T
V
L
E
H
Site 27
T264
S
I
H
S
S
T
K
T
V
L
E
H
Q
P
G
Site 28
T284
P
G
K
K
R
G
R
T
P
K
T
L
I
S
H
Site 29
T287
K
R
G
R
T
P
K
T
L
I
S
H
P
I
S
Site 30
S290
R
T
P
K
T
L
I
S
H
P
I
S
A
P
S
Site 31
S294
T
L
I
S
H
P
I
S
A
P
S
K
T
A
E
Site 32
S297
S
H
P
I
S
A
P
S
K
T
A
E
P
L
K
Site 33
S315
K
R
G
P
K
P
G
S
K
R
K
P
R
T
L
Site 34
T321
G
S
K
R
K
P
R
T
L
L
N
P
P
P
A
Site 35
S329
L
L
N
P
P
P
A
S
P
T
T
S
T
P
E
Site 36
T332
P
P
P
A
S
P
T
T
S
T
P
E
P
D
T
Site 37
S333
P
P
A
S
P
T
T
S
T
P
E
P
D
T
S
Site 38
T334
P
A
S
P
T
T
S
T
P
E
P
D
T
S
T
Site 39
S340
S
T
P
E
P
D
T
S
T
V
P
Q
D
A
A
Site 40
T341
T
P
E
P
D
T
S
T
V
P
Q
D
A
A
T
Site 41
T348
T
V
P
Q
D
A
A
T
I
P
S
S
A
M
Q
Site 42
Y362
Q
A
P
T
V
C
I
Y
L
N
K
N
G
S
T
Site 43
S368
I
Y
L
N
K
N
G
S
T
G
P
H
L
D
K
Site 44
S425
G
H
G
G
E
V
I
S
A
V
F
D
R
E
Q
Site 45
T469
L
F
G
N
Q
P
F
T
Q
T
H
L
S
L
T
Site 46
S474
P
F
T
Q
T
H
L
S
L
T
A
I
E
Y
S
Site 47
T476
T
Q
T
H
L
S
L
T
A
I
E
Y
S
H
S
Site 48
S483
T
A
I
E
Y
S
H
S
H
D
R
Y
L
P
G
Site 49
Y487
Y
S
H
S
H
D
R
Y
L
P
G
E
T
F
V
Site 50
S498
E
T
F
V
L
G
N
S
L
A
R
S
L
E
P
Site 51
S502
L
G
N
S
L
A
R
S
L
E
P
H
S
D
S
Site 52
S507
A
R
S
L
E
P
H
S
D
S
M
D
S
A
S
Site 53
S509
S
L
E
P
H
S
D
S
M
D
S
A
S
N
P
Site 54
S512
P
H
S
D
S
M
D
S
A
S
N
P
T
N
L
Site 55
S514
S
D
S
M
D
S
A
S
N
P
T
N
L
V
S
Site 56
S521
S
N
P
T
N
L
V
S
T
S
Q
R
H
R
P
Site 57
S523
P
T
N
L
V
S
T
S
Q
R
H
R
P
L
L
Site 58
S531
Q
R
H
R
P
L
L
S
S
C
G
L
P
P
S
Site 59
S532
R
H
R
P
L
L
S
S
C
G
L
P
P
S
T
Site 60
S538
S
S
C
G
L
P
P
S
T
A
S
A
V
R
R
Site 61
T539
S
C
G
L
P
P
S
T
A
S
A
V
R
R
L
Site 62
S541
G
L
P
P
S
T
A
S
A
V
R
R
L
C
S
Site 63
S548
S
A
V
R
R
L
C
S
R
G
V
L
K
G
S
Site 64
S555
S
R
G
V
L
K
G
S
N
E
R
R
D
M
E
Site 65
S563
N
E
R
R
D
M
E
S
F
W
K
L
N
R
S
Site 66
S570
S
F
W
K
L
N
R
S
P
G
S
D
R
Y
L
Site 67
S573
K
L
N
R
S
P
G
S
D
R
Y
L
E
S
R
Site 68
Y576
R
S
P
G
S
D
R
Y
L
E
S
R
D
A
S
Site 69
S579
G
S
D
R
Y
L
E
S
R
D
A
S
R
L
S
Site 70
S583
Y
L
E
S
R
D
A
S
R
L
S
G
R
D
P
Site 71
S586
S
R
D
A
S
R
L
S
G
R
D
P
S
S
W
Site 72
S591
R
L
S
G
R
D
P
S
S
W
T
V
E
D
V
Site 73
S592
L
S
G
R
D
P
S
S
W
T
V
E
D
V
M
Site 74
Y637
R
S
D
M
M
M
K
Y
M
G
L
K
L
G
P
Site 75
S649
L
G
P
A
L
K
L
S
Y
H
I
D
R
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation