PhosphoNET

           
Protein Info 
   
Short Name:  MED8
Full Name:  Mediator of RNA polymerase II transcription subunit 8
Alias:  Activator-recruited cofactor 32 kDa component; ARC32; Mediator complex 8; Mediator complex subunit 8; Mediator of RNA polymerase II transcription 8; MGC17544; MGC19641
Type: 
Mass (Da):  29080
Number AA: 
UniProt ID:  Q96G25
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016592     Uniprot OncoNet
Molecular Function:  GO:0016455     PhosphoSite+ KinaseNET
Biological Process:  GO:0019941  GO:0006357  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11EEKQLEASLDALLSQ
Site 2S28DLKNSLGSFICKLEN
Site 3Y37ICKLENEYGRLTWPS
Site 4T41ENEYGRLTWPSVLDS
Site 5T68KVLKHEKTPLFRNQV
Site 6S82VIIPLVLSPDRDEDL
Site 7T93DEDLMRQTEGRVPVF
Site 8S101EGRVPVFSHEVVPDH
Site 9T125EEQEKQLTTDAARIG
Site 10S142AAQKQIQSLNKMCSN
Site 11S148QSLNKMCSNLLEKIS
Site 12S155SNLLEKISKEERESE
Site 13S161ISKEERESESGGLRP
Site 14T172GLRPNKQTFNPTDTN
Site 15S192VAFGKGLSNWRPSGS
Site 16S197GLSNWRPSGSSGPGQ
Site 17S199SNWRPSGSSGPGQAG
Site 18S200NWRPSGSSGPGQAGQ
Site 19S230VQMAGAPSQQQPMLS
Site 20S237SQQQPMLSGVQMAQA
Site 21S252GQPGKMPSGIKTNIK
Site 22T256KMPSGIKTNIKSASM
Site 23S260GIKTNIKSASMHPYQ
Site 24S262KTNIKSASMHPYQR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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