PhosphoNET

           
Protein Info 
   
Short Name:  LASS2
Full Name:  LAG1 longevity assurance homolog 2
Alias:  SP260;Tumor metastasis-suppressor gene 1 protein
Type: 
Mass (Da):  44876
Number AA:  380
UniProt ID:  Q96G23
International Prot ID:  IPI00305304
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016021  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0043565  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T21LWLPVNLTWADLEDR
Site 2Y33EDRDGRVYAKASDLY
Site 3S104QVEVELLSRQSGLSG
Site 4S107VELLSRQSGLSGRQV
Site 5S110LSRQSGLSGRQVERW
Site 6S128RRNQDRPSLLKKFRE
Site 7S137LKKFREASWRFTFYL
Site 8Y170MKKVWEGYPIQSTIP
Site 9Y182TIPSQYWYYMIELSF
Site 10S199SLLFSIASDVKRKDF
Site 11Y244ALHDSSDYLLESAKM
Site 12S248SSDYLLESAKMFNYA
Site 13S341KLVEDERSDREETES
Site 14T346ERSDREETESSEGEE
Site 15S348SDREETESSEGEEAA
Site 16S349DREETESSEGEEAAA
Site 17S362AAGGGAKSRPLANGH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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