KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CPNE2
Full Name:
Copine-2
Alias:
Copine II
Type:
Mass (Da):
61190
Number AA:
548
UniProt ID:
Q96FN4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y21
A
A
P
M
G
P
Q
Y
C
V
C
K
V
E
L
Site 2
S31
C
K
V
E
L
S
V
S
G
Q
N
L
L
D
R
Site 3
T41
N
L
L
D
R
D
V
T
S
K
S
D
P
F
C
Site 4
S42
L
L
D
R
D
V
T
S
K
S
D
P
F
C
V
Site 5
S44
D
R
D
V
T
S
K
S
D
P
F
C
V
L
F
Site 6
Y61
N
N
G
R
W
I
E
Y
D
R
T
E
T
A
I
Site 7
T64
R
W
I
E
Y
D
R
T
E
T
A
I
N
N
L
Site 8
T66
I
E
Y
D
R
T
E
T
A
I
N
N
L
N
P
Site 9
S76
N
N
L
N
P
A
F
S
K
K
F
V
L
D
Y
Site 10
Y83
S
K
K
F
V
L
D
Y
H
F
E
E
V
Q
K
Site 11
S101
A
L
F
D
Q
D
K
S
S
M
R
L
D
E
H
Site 12
S102
L
F
D
Q
D
K
S
S
M
R
L
D
E
H
D
Site 13
S123
C
S
L
G
T
I
V
S
S
K
K
I
T
R
P
Site 14
S124
S
L
G
T
I
V
S
S
K
K
I
T
R
P
L
Site 15
T158
L
S
D
N
R
V
I
T
L
S
L
A
G
R
R
Site 16
S160
D
N
R
V
I
T
L
S
L
A
G
R
R
L
D
Site 17
S175
K
K
D
L
F
G
K
S
D
P
F
L
E
F
Y
Site 18
Y182
S
D
P
F
L
E
F
Y
K
P
G
D
D
G
K
Site 19
Y201
H
R
T
E
V
I
K
Y
T
L
D
P
V
W
K
Site 20
T202
R
T
E
V
I
K
Y
T
L
D
P
V
W
K
P
Site 21
Y231
K
P
I
Q
V
M
C
Y
D
Y
D
N
D
G
G
Site 22
Y233
I
Q
V
M
C
Y
D
Y
D
N
D
G
G
H
D
Site 23
S250
G
E
F
Q
T
S
V
S
Q
M
C
E
A
R
D
Site 24
S258
Q
M
C
E
A
R
D
S
V
P
L
E
F
E
C
Site 25
Y277
K
Q
R
K
K
K
N
Y
K
N
S
G
I
I
I
Site 26
S280
K
K
K
N
Y
K
N
S
G
I
I
I
L
R
S
Site 27
Y294
S
C
K
I
N
R
D
Y
S
F
L
D
Y
I
L
Site 28
S325
N
G
N
P
L
D
P
S
S
L
H
Y
I
N
P
Site 29
S326
G
N
P
L
D
P
S
S
L
H
Y
I
N
P
M
Site 30
Y329
L
D
P
S
S
L
H
Y
I
N
P
M
G
T
N
Site 31
Y352
V
G
Q
I
I
Q
D
Y
D
S
D
K
M
F
P
Site 32
Y408
C
L
P
H
I
R
F
Y
G
P
T
N
F
S
P
Site 33
T428
A
R
F
A
A
Q
A
T
Q
Q
R
T
A
T
Q
Site 34
S448
I
I
T
D
G
V
I
S
D
M
E
E
T
R
H
Site 35
S487
M
E
F
L
D
G
D
S
R
M
L
R
S
H
T
Site 36
S492
G
D
S
R
M
L
R
S
H
T
G
E
E
A
A
Site 37
T494
S
R
M
L
R
S
H
T
G
E
E
A
A
R
D
Site 38
Y534
L
P
Q
Q
V
V
Q
Y
F
K
H
K
N
L
P
Site 39
T543
K
H
K
N
L
P
P
T
N
S
E
P
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation