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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCRS1
Full Name:
Microspherule protein 1
Alias:
58 kDa microspherule protein; Cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; INO80 complex subunit Q; INO80Q; MCRS2; Microspherule protein 1; MSP58; P78
Type:
RNA binding protein; Nuclear receptor co-regulator
Mass (Da):
51803
Number AA:
462
UniProt ID:
Q96EZ8
International Prot ID:
IPI00220477
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
D
K
D
S
Q
G
L
L
D
S
S
Site 2
S11
D
S
Q
G
L
L
D
S
S
L
M
A
S
G
T
Site 3
S12
S
Q
G
L
L
D
S
S
L
M
A
S
G
T
A
Site 4
S16
L
D
S
S
L
M
A
S
G
T
A
S
R
S
E
Site 5
T18
S
S
L
M
A
S
G
T
A
S
R
S
E
D
E
Site 6
S20
L
M
A
S
G
T
A
S
R
S
E
D
E
E
S
Site 7
S22
A
S
G
T
A
S
R
S
E
D
E
E
S
L
A
Site 8
S27
S
R
S
E
D
E
E
S
L
A
G
Q
K
R
A
Site 9
S35
L
A
G
Q
K
R
A
S
S
Q
A
L
G
T
I
Site 10
S36
A
G
Q
K
R
A
S
S
Q
A
L
G
T
I
P
Site 11
S47
G
T
I
P
K
R
R
S
S
S
R
F
I
K
R
Site 12
S48
T
I
P
K
R
R
S
S
S
R
F
I
K
R
K
Site 13
S49
I
P
K
R
R
S
S
S
R
F
I
K
R
K
K
Site 14
S64
F
D
D
E
L
V
E
S
S
L
A
K
S
S
T
Site 15
S65
D
D
E
L
V
E
S
S
L
A
K
S
S
T
R
Site 16
S69
V
E
S
S
L
A
K
S
S
T
R
A
K
G
A
Site 17
S70
E
S
S
L
A
K
S
S
T
R
A
K
G
A
S
Site 18
T71
S
S
L
A
K
S
S
T
R
A
K
G
A
S
G
Site 19
S77
S
T
R
A
K
G
A
S
G
V
E
P
G
R
C
Site 20
S85
G
V
E
P
G
R
C
S
G
S
E
P
S
S
S
Site 21
S87
E
P
G
R
C
S
G
S
E
P
S
S
S
E
K
Site 22
S91
C
S
G
S
E
P
S
S
S
E
K
K
K
V
S
Site 23
S92
S
G
S
E
P
S
S
S
E
K
K
K
V
S
K
Site 24
S98
S
S
E
K
K
K
V
S
K
A
P
S
T
P
V
Site 25
S102
K
K
V
S
K
A
P
S
T
P
V
P
P
S
P
Site 26
T103
K
V
S
K
A
P
S
T
P
V
P
P
S
P
A
Site 27
S108
P
S
T
P
V
P
P
S
P
A
P
A
P
G
L
Site 28
T116
P
A
P
A
P
G
L
T
K
R
V
K
K
S
K
Site 29
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Site 30
T167
V
K
F
S
C
R
F
T
L
R
E
V
Q
E
R
Site 31
Y176
R
E
V
Q
E
R
W
Y
A
L
L
Y
D
P
V
Site 32
Y180
E
R
W
Y
A
L
L
Y
D
P
V
I
S
K
L
Site 33
S218
K
A
E
E
Q
L
L
S
K
V
G
S
T
S
Q
Site 34
S222
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Site 35
S224
L
S
K
V
G
S
T
S
Q
P
T
L
E
T
F
Site 36
T230
T
S
Q
P
T
L
E
T
F
Q
D
L
L
H
R
Site 37
Y243
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Site 38
Y262
W
Q
L
M
K
Q
Y
Y
L
L
E
D
Q
T
V
Site 39
T268
Y
Y
L
L
E
D
Q
T
V
Q
P
L
P
K
G
Site 40
S282
G
D
Q
V
L
N
F
S
D
A
E
D
L
I
D
Site 41
S291
A
E
D
L
I
D
D
S
K
L
K
D
M
R
D
Site 42
S332
K
W
Q
V
L
V
D
S
I
T
G
M
S
S
P
Site 43
S338
D
S
I
T
G
M
S
S
P
D
F
D
N
Q
T
Site 44
T345
S
P
D
F
D
N
Q
T
L
A
V
L
R
G
R
Site 45
Y356
L
R
G
R
M
V
R
Y
L
M
R
S
R
E
I
Site 46
S360
M
V
R
Y
L
M
R
S
R
E
I
T
L
G
R
Site 47
T364
L
M
R
S
R
E
I
T
L
G
R
A
T
K
D
Site 48
T369
E
I
T
L
G
R
A
T
K
D
N
Q
I
D
V
Site 49
S379
N
Q
I
D
V
D
L
S
L
E
G
P
A
W
K
Site 50
S388
E
G
P
A
W
K
I
S
R
K
Q
G
V
I
K
Site 51
Y413
N
E
G
R
R
P
I
Y
I
D
G
R
P
V
L
Site 52
S423
G
R
P
V
L
C
G
S
K
W
R
L
S
N
N
Site 53
S428
C
G
S
K
W
R
L
S
N
N
S
V
V
E
I
Site 54
S431
K
W
R
L
S
N
N
S
V
V
E
I
A
S
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation