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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF31
Full Name:
RING finger protein 31
Alias:
FLJ10111; FLJ23501; Ring finger 31; Ring finger protein 31; ZIBRA; Zinc in-between-RING-finger ubiquitin-associated domain
Type:
Mass (Da):
119650
Number AA:
UniProt ID:
Q96EP0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
V
A
R
E
E
L
A
S
A
L
R
R
D
S
G
Site 2
S25
A
S
A
L
R
R
D
S
G
Q
A
F
S
L
E
Site 3
S30
R
D
S
G
Q
A
F
S
L
E
Q
L
R
P
L
Site 4
Y68
A
H
G
E
P
R
N
Y
L
N
T
L
S
T
A
Site 5
T71
E
P
R
N
Y
L
N
T
L
S
T
A
L
N
I
Site 6
Y82
A
L
N
I
L
E
K
Y
G
R
N
L
L
S
P
Site 7
S88
K
Y
G
R
N
L
L
S
P
Q
R
P
R
Y
W
Site 8
Y94
L
S
P
Q
R
P
R
Y
W
R
G
V
K
F
N
Site 9
T108
N
N
P
V
F
R
S
T
V
D
A
V
Q
G
G
Site 10
Y122
G
R
D
V
L
R
L
Y
G
Y
T
E
E
Q
P
Site 11
Y124
D
V
L
R
L
Y
G
Y
T
E
E
Q
P
D
G
Site 12
S133
E
E
Q
P
D
G
L
S
F
P
E
G
Q
E
E
Site 13
T167
L
S
L
L
L
Q
N
T
H
P
R
Q
Q
A
L
Site 14
S190
E
D
D
M
L
Q
L
S
E
F
D
P
L
L
R
Site 15
T205
E
I
A
P
G
P
L
T
T
P
S
V
P
G
S
Site 16
S208
P
G
P
L
T
T
P
S
V
P
G
S
T
P
G
Site 17
T257
R
A
H
H
L
R
Q
T
L
P
G
V
L
Q
G
Site 18
S270
Q
G
T
H
L
S
P
S
L
P
A
S
A
Q
P
Site 19
S274
L
S
P
S
L
P
A
S
A
Q
P
R
P
Q
S
Site 20
S281
S
A
Q
P
R
P
Q
S
T
S
L
L
A
L
G
Site 21
S283
Q
P
R
P
Q
S
T
S
L
L
A
L
G
D
S
Site 22
S290
S
L
L
A
L
G
D
S
S
L
S
S
P
N
P
Site 23
S293
A
L
G
D
S
S
L
S
S
P
N
P
A
S
A
Site 24
S294
L
G
D
S
S
L
S
S
P
N
P
A
S
A
H
Site 25
S299
L
S
S
P
N
P
A
S
A
H
L
P
W
H
C
Site 26
T336
C
K
G
L
G
L
G
T
E
G
P
Q
G
T
G
Site 27
S383
P
R
L
A
Q
P
P
S
L
V
V
D
S
R
D
Site 28
S407
Q
G
D
A
L
L
A
S
A
Q
S
Q
V
W
Y
Site 29
S437
V
M
C
N
R
T
S
S
P
I
P
A
Q
H
A
Site 30
Y448
A
Q
H
A
P
R
P
Y
A
S
S
L
E
K
G
Site 31
S451
A
P
R
P
Y
A
S
S
L
E
K
G
P
P
K
Site 32
S466
P
G
P
P
R
R
L
S
A
P
L
P
S
S
C
Site 33
S471
R
L
S
A
P
L
P
S
S
C
G
D
P
E
K
Site 34
S472
L
S
A
P
L
P
S
S
C
G
D
P
E
K
Q
Site 35
S493
E
E
G
L
Q
L
V
S
M
I
R
E
G
E
A
Site 36
S510
A
C
P
E
E
I
F
S
A
L
Q
Y
S
G
T
Site 37
T517
S
A
L
Q
Y
S
G
T
E
V
P
L
Q
W
L
Site 38
T575
A
V
E
E
C
V
R
T
R
R
R
K
V
Q
E
Site 39
S594
G
F
G
P
E
E
G
S
L
Q
A
L
F
Q
H
Site 40
T610
G
D
V
S
R
A
L
T
E
L
Q
R
Q
R
L
Site 41
S627
F
R
Q
R
L
W
D
S
G
P
E
P
T
P
S
Site 42
T632
W
D
S
G
P
E
P
T
P
S
W
D
G
P
D
Site 43
S634
S
G
P
E
P
T
P
S
W
D
G
P
D
K
Q
Site 44
S642
W
D
G
P
D
K
Q
S
L
V
R
R
L
L
A
Site 45
S664
G
R
A
E
L
A
L
S
L
L
Q
E
T
P
R
Site 46
T669
A
L
S
L
L
Q
E
T
P
R
N
Y
E
L
G
Site 47
Y673
L
Q
E
T
P
R
N
Y
E
L
G
D
V
V
E
Site 48
S685
V
V
E
A
V
R
H
S
Q
D
R
A
F
L
R
Site 49
T753
A
C
G
R
P
D
L
T
D
D
T
Q
L
L
S
Site 50
T756
R
P
D
L
T
D
D
T
Q
L
L
S
Y
F
S
Site 51
S760
T
D
D
T
Q
L
L
S
Y
F
S
T
L
D
I
Site 52
Y761
D
D
T
Q
L
L
S
Y
F
S
T
L
D
I
Q
Site 53
T764
Q
L
L
S
Y
F
S
T
L
D
I
Q
L
R
E
Site 54
S772
L
D
I
Q
L
R
E
S
L
E
P
D
A
Y
A
Site 55
Y778
E
S
L
E
P
D
A
Y
A
L
F
H
K
K
L
Site 56
Y808
Q
C
S
F
G
F
I
Y
E
R
E
Q
L
E
A
Site 57
Y855
K
R
M
N
D
P
E
Y
Q
A
Q
G
L
A
M
Site 58
Y863
Q
A
Q
G
L
A
M
Y
L
Q
E
N
G
I
D
Site 59
S877
D
C
P
K
C
K
F
S
Y
A
L
A
R
G
G
Site 60
Y878
C
P
K
C
K
F
S
Y
A
L
A
R
G
G
C
Site 61
Y906
S
G
C
Y
N
A
F
Y
A
K
N
K
C
P
E
Site 62
S921
P
N
C
R
V
K
K
S
L
H
G
H
H
P
R
Site 63
Y933
H
P
R
D
C
L
F
Y
L
R
D
W
T
A
L
Site 64
T955
D
N
N
V
M
F
N
T
E
P
P
A
G
A
R
Site 65
T990
D
E
A
C
G
K
E
T
P
A
G
Y
A
G
L
Site 66
S1008
H
Y
K
E
Y
L
V
S
L
I
N
A
H
S
L
Site 67
T1019
A
H
S
L
D
P
A
T
L
Y
E
V
E
E
L
Site 68
Y1021
S
L
D
P
A
T
L
Y
E
V
E
E
L
E
T
Site 69
Y1033
L
E
T
A
T
E
R
Y
L
H
V
R
P
Q
P
Site 70
Y1049
A
G
E
D
P
P
A
Y
Q
A
R
L
L
Q
K
Site 71
T1058
A
R
L
L
Q
K
L
T
E
E
V
P
L
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation