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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MOCOS
Full Name:
Molybdenum cofactor sulfurase
Alias:
HMCS; Molybdenum cofactor sulfurase: HMCS: MOS
Type:
Enzyme, sulfurase
Mass (Da):
98153
Number AA:
888
UniProt ID:
Q96EN8
International Prot ID:
IPI00304895
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008265
GO:0016829
GO:0030151
PhosphoSite+
KinaseNET
Biological Process:
GO:0006777
GO:0006732
GO:0006777
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
G
A
A
A
E
S
G
R
E
L
W
T
F
Site 2
T14
E
S
G
R
E
L
W
T
F
A
G
S
R
D
P
Site 3
S18
E
L
W
T
F
A
G
S
R
D
P
S
A
P
R
Site 4
S22
F
A
G
S
R
D
P
S
A
P
R
L
A
Y
G
Site 5
Y28
P
S
A
P
R
L
A
Y
G
Y
G
P
G
S
L
Site 6
Y30
A
P
R
L
A
Y
G
Y
G
P
G
S
L
R
E
Site 7
S34
A
Y
G
Y
G
P
G
S
L
R
E
L
R
A
R
Site 8
S44
E
L
R
A
R
E
F
S
R
L
A
G
T
V
Y
Site 9
T49
E
F
S
R
L
A
G
T
V
Y
L
D
H
A
G
Site 10
S61
H
A
G
A
T
L
F
S
Q
S
Q
L
E
S
F
Site 11
S63
G
A
T
L
F
S
Q
S
Q
L
E
S
F
T
S
Site 12
S67
F
S
Q
S
Q
L
E
S
F
T
S
D
L
M
E
Site 13
S70
S
Q
L
E
S
F
T
S
D
L
M
E
N
T
Y
Site 14
Y77
S
D
L
M
E
N
T
Y
G
N
P
H
S
Q
N
Site 15
S82
N
T
Y
G
N
P
H
S
Q
N
I
S
S
K
L
Site 16
S86
N
P
H
S
Q
N
I
S
S
K
L
T
H
D
T
Site 17
T90
Q
N
I
S
S
K
L
T
H
D
T
V
E
Q
V
Site 18
T93
S
S
K
L
T
H
D
T
V
E
Q
V
R
Y
R
Site 19
Y99
D
T
V
E
Q
V
R
Y
R
I
L
A
H
F
H
Site 20
T113
H
T
T
A
E
D
Y
T
V
I
F
T
A
G
S
Site 21
S135
A
E
A
F
P
W
V
S
Q
G
P
E
S
S
G
Site 22
S140
W
V
S
Q
G
P
E
S
S
G
S
R
F
C
Y
Site 23
S141
V
S
Q
G
P
E
S
S
G
S
R
F
C
Y
L
Site 24
S143
Q
G
P
E
S
S
G
S
R
F
C
Y
L
T
D
Site 25
Y147
S
S
G
S
R
F
C
Y
L
T
D
S
H
T
S
Site 26
T149
G
S
R
F
C
Y
L
T
D
S
H
T
S
V
V
Site 27
T153
C
Y
L
T
D
S
H
T
S
V
V
G
M
R
N
Site 28
S179
V
R
P
E
D
L
W
S
A
E
E
R
G
A
S
Site 29
S186
S
A
E
E
R
G
A
S
A
S
N
P
D
C
Q
Site 30
S188
E
E
R
G
A
S
A
S
N
P
D
C
Q
L
P
Site 31
Y200
Q
L
P
H
L
F
C
Y
P
A
Q
S
N
F
S
Site 32
Y211
S
N
F
S
G
V
R
Y
P
L
S
W
I
E
E
Site 33
S214
S
G
V
R
Y
P
L
S
W
I
E
E
V
K
S
Site 34
S221
S
W
I
E
E
V
K
S
G
R
L
R
P
V
S
Site 35
S228
S
G
R
L
R
P
V
S
T
P
G
K
W
F
V
Site 36
T229
G
R
L
R
P
V
S
T
P
G
K
W
F
V
L
Site 37
T245
D
A
A
S
Y
V
S
T
S
P
L
D
L
S
A
Site 38
S246
A
A
S
Y
V
S
T
S
P
L
D
L
S
A
H
Site 39
S251
S
T
S
P
L
D
L
S
A
H
Q
A
D
F
V
Site 40
Y289
A
P
L
L
R
K
T
Y
F
G
G
G
T
A
S
Site 41
S296
Y
F
G
G
G
T
A
S
A
Y
L
A
G
E
D
Site 42
Y298
G
G
G
T
A
S
A
Y
L
A
G
E
D
F
Y
Site 43
Y305
Y
L
A
G
E
D
F
Y
I
P
R
Q
S
V
A
Site 44
S310
D
F
Y
I
P
R
Q
S
V
A
Q
R
F
E
D
Site 45
T334
A
L
K
H
G
F
D
T
L
E
R
L
T
G
G
Site 46
T339
F
D
T
L
E
R
L
T
G
G
M
E
N
I
K
Site 47
Y375
G
A
P
V
V
R
I
Y
S
D
S
E
F
S
S
Site 48
S376
A
P
V
V
R
I
Y
S
D
S
E
F
S
S
P
Site 49
S378
V
V
R
I
Y
S
D
S
E
F
S
S
P
E
V
Site 50
S382
Y
S
D
S
E
F
S
S
P
E
V
Q
G
P
I
Site 51
S405
K
G
N
I
I
G
Y
S
Q
V
D
K
M
A
S
Site 52
S412
S
Q
V
D
K
M
A
S
L
Y
N
I
H
L
R
Site 53
Y414
V
D
K
M
A
S
L
Y
N
I
H
L
R
T
G
Site 54
S464
I
D
G
Q
P
T
G
S
V
R
I
S
F
G
Y
Site 55
T488
F
L
R
F
I
I
D
T
R
L
H
S
S
G
D
Site 56
S492
I
I
D
T
R
L
H
S
S
G
D
W
P
V
P
Site 57
S515
T
G
A
P
S
A
D
S
Q
A
D
V
I
P
A
Site 58
S528
P
A
V
M
G
R
R
S
L
S
P
Q
E
D
A
Site 59
S530
V
M
G
R
R
S
L
S
P
Q
E
D
A
L
T
Site 60
T537
S
P
Q
E
D
A
L
T
G
S
R
V
W
N
N
Site 61
S539
Q
E
D
A
L
T
G
S
R
V
W
N
N
S
S
Site 62
S545
G
S
R
V
W
N
N
S
S
T
V
N
A
V
P
Site 63
T547
R
V
W
N
N
S
S
T
V
N
A
V
P
V
A
Site 64
T566
D
V
A
R
T
Q
P
T
P
S
E
K
A
A
G
Site 65
S627
N
H
N
G
V
C
L
S
Q
K
Q
E
P
R
L
Site 66
S666
E
V
P
L
E
E
N
S
E
R
T
Q
I
R
Q
Site 67
S674
E
R
T
Q
I
R
Q
S
R
V
C
A
D
R
V
Site 68
S682
R
V
C
A
D
R
V
S
T
Y
D
C
G
E
K
Site 69
T683
V
C
A
D
R
V
S
T
Y
D
C
G
E
K
I
Site 70
Y684
C
A
D
R
V
S
T
Y
D
C
G
E
K
I
S
Site 71
S692
D
C
G
E
K
I
S
S
W
L
S
T
F
F
G
Site 72
S695
E
K
I
S
S
W
L
S
T
F
F
G
R
P
C
Site 73
T696
K
I
S
S
W
L
S
T
F
F
G
R
P
C
H
Site 74
S709
C
H
L
I
K
Q
S
S
N
S
Q
R
N
A
K
Site 75
S711
L
I
K
Q
S
S
N
S
Q
R
N
A
K
K
K
Site 76
S732
P
G
T
M
A
T
L
S
L
V
N
E
A
Q
Y
Site 77
S757
L
H
R
Q
L
N
T
S
D
E
N
G
K
E
E
Site 78
S767
N
G
K
E
E
L
F
S
L
K
D
L
S
L
R
Site 79
S796
E
E
K
W
D
E
I
S
I
G
S
L
R
F
Q
Site 80
S832
Q
H
V
F
Q
K
L
S
E
S
R
E
T
K
V
Site 81
S834
V
F
Q
K
L
S
E
S
R
E
T
K
V
N
F
Site 82
T837
K
L
S
E
S
R
E
T
K
V
N
F
G
M
Y
Site 83
S880
E
G
H
D
L
P
A
S
E
K
H
Q
D
V
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation