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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DGCR14
Full Name:
Protein DGCR14
Alias:
DGC14; DGCR13; DGS-H; DGSI; DGS-I; DiGeorge syndrome critical region 14; DiGeorge syndrome critical region gene 14; ES2; Es2el; Ese2el; Protein DGCR14: DiGeorge syndrome critical region 14: DiGeorge syndrome critical region 13: DiGeorge syndrome protein H: Protein ES2
Type:
RNA processing; RNA binding protein
Mass (Da):
52568
Number AA:
476
UniProt ID:
Q96DF8
International Prot ID:
IPI00165171
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005681
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
E
T
P
G
A
S
A
S
S
Site 2
S7
_
M
E
T
P
G
A
S
A
S
S
L
L
L
P
Site 3
S9
E
T
P
G
A
S
A
S
S
L
L
L
P
A
A
Site 4
S10
T
P
G
A
S
A
S
S
L
L
L
P
A
A
S
Site 5
S17
S
L
L
L
P
A
A
S
R
P
P
R
K
R
E
Site 6
S33
G
E
A
G
A
A
T
S
K
Q
R
V
L
D
E
Site 7
Y43
R
V
L
D
E
E
E
Y
I
E
G
L
Q
T
V
Site 8
T49
E
Y
I
E
G
L
Q
T
V
I
Q
R
D
F
F
Site 9
S95
G
S
A
L
G
K
M
S
R
E
P
P
P
P
Y
Site 10
Y102
S
R
E
P
P
P
P
Y
V
T
P
A
T
F
E
Site 11
T104
E
P
P
P
P
Y
V
T
P
A
T
F
E
T
P
Site 12
T107
P
P
Y
V
T
P
A
T
F
E
T
P
E
V
H
Site 13
T110
V
T
P
A
T
F
E
T
P
E
V
H
A
G
T
Site 14
S147
E
E
K
E
P
L
P
S
L
D
V
F
L
S
R
Site 15
S153
P
S
L
D
V
F
L
S
R
Y
T
S
E
D
N
Site 16
T156
D
V
F
L
S
R
Y
T
S
E
D
N
A
S
F
Site 17
S157
V
F
L
S
R
Y
T
S
E
D
N
A
S
F
Q
Site 18
S162
Y
T
S
E
D
N
A
S
F
Q
E
I
M
E
V
Site 19
Y182
R
A
R
H
A
W
L
Y
Q
A
E
E
E
F
E
Site 20
S208
A
E
H
Q
A
I
E
S
S
Q
A
S
V
E
T
Site 21
S209
E
H
Q
A
I
E
S
S
Q
A
S
V
E
T
W
Site 22
S212
A
I
E
S
S
Q
A
S
V
E
T
W
K
Y
K
Site 23
Y218
A
S
V
E
T
W
K
Y
K
A
K
N
S
L
M
Site 24
Y227
A
K
N
S
L
M
Y
Y
P
E
G
V
P
D
E
Site 25
S257
R
F
L
R
D
P
F
S
Q
A
L
S
R
C
Q
Site 26
S261
D
P
F
S
Q
A
L
S
R
C
Q
L
Q
Q
A
Site 27
S292
K
E
L
I
P
Q
E
S
P
R
V
G
G
F
G
Site 28
S313
P
A
P
G
V
N
E
S
P
M
M
T
W
G
E
Site 29
T317
V
N
E
S
P
M
M
T
W
G
E
V
E
N
T
Site 30
T324
T
W
G
E
V
E
N
T
P
L
R
V
E
G
S
Site 31
S331
T
P
L
R
V
E
G
S
E
T
P
Y
V
D
R
Site 32
T333
L
R
V
E
G
S
E
T
P
Y
V
D
R
T
P
Site 33
Y335
V
E
G
S
E
T
P
Y
V
D
R
T
P
G
P
Site 34
T339
E
T
P
Y
V
D
R
T
P
G
P
A
F
K
I
Site 35
T379
Q
E
A
L
R
R
V
T
E
N
L
A
S
L
T
Site 36
S384
R
V
T
E
N
L
A
S
L
T
P
K
G
L
S
Site 37
T386
T
E
N
L
A
S
L
T
P
K
G
L
S
P
A
Site 38
S391
S
L
T
P
K
G
L
S
P
A
M
S
P
A
L
Site 39
S395
K
G
L
S
P
A
M
S
P
A
L
Q
R
L
V
Site 40
S403
P
A
L
Q
R
L
V
S
R
T
A
S
K
Y
T
Site 41
T405
L
Q
R
L
V
S
R
T
A
S
K
Y
T
D
R
Site 42
S407
R
L
V
S
R
T
A
S
K
Y
T
D
R
A
L
Site 43
Y409
V
S
R
T
A
S
K
Y
T
D
R
A
L
R
A
Site 44
S417
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Site 45
T419
R
A
L
R
A
S
Y
T
P
S
P
A
R
S
T
Site 46
S421
L
R
A
S
Y
T
P
S
P
A
R
S
T
H
L
Site 47
S425
Y
T
P
S
P
A
R
S
T
H
L
K
T
P
A
Site 48
T426
T
P
S
P
A
R
S
T
H
L
K
T
P
A
S
Site 49
T430
A
R
S
T
H
L
K
T
P
A
S
G
L
Q
T
Site 50
S433
T
H
L
K
T
P
A
S
G
L
Q
T
P
T
S
Site 51
T437
T
P
A
S
G
L
Q
T
P
T
S
T
P
A
P
Site 52
T439
A
S
G
L
Q
T
P
T
S
T
P
A
P
G
S
Site 53
S440
S
G
L
Q
T
P
T
S
T
P
A
P
G
S
A
Site 54
T441
G
L
Q
T
P
T
S
T
P
A
P
G
S
A
T
Site 55
S446
T
S
T
P
A
P
G
S
A
T
R
T
P
L
T
Site 56
T450
A
P
G
S
A
T
R
T
P
L
T
Q
D
P
A
Site 57
T453
S
A
T
R
T
P
L
T
Q
D
P
A
S
I
T
Site 58
S458
P
L
T
Q
D
P
A
S
I
T
D
N
L
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation