PhosphoNET

           
Protein Info 
   
Short Name:  INTS12
Full Name:  Integrator complex subunit 12
Alias:  INT12; Nuclear factor SBBI22; PHD finger protein 22; SBBI22
Type:  RNA binding protein
Mass (Da):  48808
Number AA:  462
UniProt ID:  Q96CB8
International Prot ID:  IPI00060379
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0032039  GO:0032039  GO:0032991 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008270  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0016180  GO:0006396  GO:0008152 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22KALGFLHSKSKDSAE
Site 2S24LGFLHSKSKDSAEKL
Site 3S45SLARGIDSSYRPSQK
Site 4S46LARGIDSSYRPSQKD
Site 5Y47ARGIDSSYRPSQKDV
Site 6S50IDSSYRPSQKDVEPP
Site 7T62EPPKISSTKNISIKQ
Site 8S74IKQEPKISSSLPSGN
Site 9S75KQEPKISSSLPSGNN
Site 10S76QEPKISSSLPSGNNN
Site 11S79KISSSLPSGNNNGKV
Site 12S106RPADKMKSDITEGVD
Site 13T109DKMKSDITEGVDIPK
Site 14T125PRLEKPETQSSPITV
Site 15S127LEKPETQSSPITVQS
Site 16S128EKPETQSSPITVQSS
Site 17T131ETQSSPITVQSSKDL
Site 18S134SSPITVQSSKDLPMA
Site 19S144DLPMADLSSFEETSA
Site 20S145LPMADLSSFEETSAD
Site 21S150LSSFEETSADDFAME
Site 22T223MKRMAQKTQKPPQKP
Site 23T258TKLKQETTFLAFKRT
Site 24T265TFLAFKRTEVKTSTV
Site 25T269FKRTEVKTSTVISGN
Site 26S270KRTEVKTSTVISGNS
Site 27T271RTEVKTSTVISGNSS
Site 28S274VKTSTVISGNSSSAS
Site 29S277STVISGNSSSASVSS
Site 30S278TVISGNSSSASVSSS
Site 31S281SGNSSSASVSSSVTS
Site 32S283NSSSASVSSSVTSGL
Site 33S284SSSASVSSSVTSGLT
Site 34T300WAAFAAKTSSAGPST
Site 35S302AFAAKTSSAGPSTAK
Site 36S306KTSSAGPSTAKLSST
Site 37T307TSSAGPSTAKLSSTT
Site 38T318SSTTQNNTGKPATSS
Site 39S325TGKPATSSANQKPVG
Site 40S340LTGLATSSKGGIGSK
Site 41S346SSKGGIGSKIGSNNS
Site 42S350GIGSKIGSNNSTTPT
Site 43S353SKIGSNNSTTPTVPL
Site 44T354KIGSNNSTTPTVPLK
Site 45T355IGSNNSTTPTVPLKP
Site 46T357SNNSTTPTVPLKPPP
Site 47T367LKPPPPLTLGKTGLS
Site 48T371PPLTLGKTGLSRSVS
Site 49S374TLGKTGLSRSVSCDN
Site 50S376GKTGLSRSVSCDNVS
Site 51S378TGLSRSVSCDNVSKV
Site 52S383SVSCDNVSKVGLPSP
Site 53S391KVGLPSPSSLVPGSS
Site 54S397PSSLVPGSSSQLSGN
Site 55S398SSLVPGSSSQLSGNG
Site 56S399SLVPGSSSQLSGNGN
Site 57S402PGSSSQLSGNGNSGT
Site 58S407QLSGNGNSGTSGPSG
Site 59T409SGNGNSGTSGPSGST
Site 60S410GNGNSGTSGPSGSTT
Site 61S413NSGTSGPSGSTTSKT
Site 62S415GTSGPSGSTTSKTTS
Site 63T417SGPSGSTTSKTTSES
Site 64S418GPSGSTTSKTTSESS
Site 65T420SGSTTSKTTSESSSS
Site 66T421GSTTSKTTSESSSSP
Site 67S422STTSKTTSESSSSPS
Site 68S424TSKTTSESSSSPSAS
Site 69S425SKTTSESSSSPSASL
Site 70S426KTTSESSSSPSASLK
Site 71S427TTSESSSSPSASLKG
Site 72S429SESSSSPSASLKGPT
Site 73S431SSSSPSASLKGPTSQ
Site 74S437ASLKGPTSQESQLNA
Site 75S440KGPTSQESQLNAMKR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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