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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB8A
Full Name:
Zinc finger and BTB domain-containing protein 8A
Alias:
BTB/POZ and zinc-finger domain-containing factor;BTB/POZ and zinc-finger domains factor on chromosome 1
Type:
Mass (Da):
50141
Number AA:
441
UniProt ID:
Q96BR9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
I
S
S
H
Q
S
H
L
L
Q
Q
L
N
Site 2
S54
G
Y
F
K
M
L
L
S
Q
N
S
K
E
T
S
Site 3
S57
K
M
L
L
S
Q
N
S
K
E
T
S
Q
P
T
Site 4
S61
S
Q
N
S
K
E
T
S
Q
P
T
T
A
T
F
Site 5
T65
K
E
T
S
Q
P
T
T
A
T
F
Q
A
F
S
Site 6
T67
T
S
Q
P
T
T
A
T
F
Q
A
F
S
P
D
Site 7
S120
V
C
K
T
F
I
K
S
S
L
D
I
S
E
K
Site 8
S121
C
K
T
F
I
K
S
S
L
D
I
S
E
K
E
Site 9
S125
I
K
S
S
L
D
I
S
E
K
E
K
D
R
Y
Site 10
Y132
S
E
K
E
K
D
R
Y
F
S
L
S
D
K
D
Site 11
S134
K
E
K
D
R
Y
F
S
L
S
D
K
D
A
N
Site 12
S136
K
D
R
Y
F
S
L
S
D
K
D
A
N
S
N
Site 13
S142
L
S
D
K
D
A
N
S
N
G
V
E
R
S
S
Site 14
S148
N
S
N
G
V
E
R
S
S
F
Y
S
G
G
W
Site 15
S149
S
N
G
V
E
R
S
S
F
Y
S
G
G
W
Q
Site 16
S152
V
E
R
S
S
F
Y
S
G
G
W
Q
E
G
S
Site 17
S159
S
G
G
W
Q
E
G
S
S
S
P
R
S
H
L
Site 18
S160
G
G
W
Q
E
G
S
S
S
P
R
S
H
L
S
Site 19
S161
G
W
Q
E
G
S
S
S
P
R
S
H
L
S
P
Site 20
S164
E
G
S
S
S
P
R
S
H
L
S
P
E
Q
G
Site 21
S167
S
S
P
R
S
H
L
S
P
E
Q
G
T
G
I
Site 22
Y183
S
G
K
S
W
N
K
Y
N
Y
H
P
A
S
Q
Site 23
Y185
K
S
W
N
K
Y
N
Y
H
P
A
S
Q
K
N
Site 24
S189
K
Y
N
Y
H
P
A
S
Q
K
N
T
Q
Q
P
Site 25
T193
H
P
A
S
Q
K
N
T
Q
Q
P
L
A
K
H
Site 26
S206
K
H
E
P
R
K
E
S
I
K
K
T
K
H
L
Site 27
T210
R
K
E
S
I
K
K
T
K
H
L
R
L
S
Q
Site 28
S216
K
T
K
H
L
R
L
S
Q
P
S
E
V
T
H
Site 29
S219
H
L
R
L
S
Q
P
S
E
V
T
H
Y
K
S
Site 30
T222
L
S
Q
P
S
E
V
T
H
Y
K
S
S
K
R
Site 31
Y224
Q
P
S
E
V
T
H
Y
K
S
S
K
R
E
V
Site 32
S226
S
E
V
T
H
Y
K
S
S
K
R
E
V
R
T
Site 33
S227
E
V
T
H
Y
K
S
S
K
R
E
V
R
T
S
Site 34
T233
S
S
K
R
E
V
R
T
S
D
S
S
S
H
V
Site 35
S234
S
K
R
E
V
R
T
S
D
S
S
S
H
V
S
Site 36
S236
R
E
V
R
T
S
D
S
S
S
H
V
S
Q
S
Site 37
S237
E
V
R
T
S
D
S
S
S
H
V
S
Q
S
E
Site 38
S238
V
R
T
S
D
S
S
S
H
V
S
Q
S
E
E
Site 39
S241
S
D
S
S
S
H
V
S
Q
S
E
E
Q
A
Q
Site 40
S243
S
S
S
H
V
S
Q
S
E
E
Q
A
Q
I
D
Site 41
T256
I
D
A
E
M
D
S
T
P
V
G
Y
Q
Y
G
Site 42
Y260
M
D
S
T
P
V
G
Y
Q
Y
G
Q
G
S
D
Site 43
Y262
S
T
P
V
G
Y
Q
Y
G
Q
G
S
D
V
T
Site 44
S266
G
Y
Q
Y
G
Q
G
S
D
V
T
S
K
S
F
Site 45
T269
Y
G
Q
G
S
D
V
T
S
K
S
F
P
D
D
Site 46
S270
G
Q
G
S
D
V
T
S
K
S
F
P
D
D
L
Site 47
S272
G
S
D
V
T
S
K
S
F
P
D
D
L
P
R
Site 48
T305
K
R
H
L
R
C
H
T
G
E
R
P
Y
P
C
Site 49
Y310
C
H
T
G
E
R
P
Y
P
C
Q
A
C
G
K
Site 50
S320
Q
A
C
G
K
R
F
S
R
L
D
H
L
S
S
Site 51
S326
F
S
R
L
D
H
L
S
S
H
F
R
T
I
H
Site 52
S327
S
R
L
D
H
L
S
S
H
F
R
T
I
H
Q
Site 53
T348
R
K
C
K
R
H
V
T
D
L
T
G
Q
V
V
Site 54
T351
K
R
H
V
T
D
L
T
G
Q
V
V
Q
E
G
Site 55
T359
G
Q
V
V
Q
E
G
T
R
R
Y
R
L
C
N
Site 56
Y362
V
Q
E
G
T
R
R
Y
R
L
C
N
E
C
L
Site 57
S389
E
A
E
Q
H
L
M
S
P
S
D
G
D
K
D
Site 58
S391
E
Q
H
L
M
S
P
S
D
G
D
K
D
S
R
Site 59
S397
P
S
D
G
D
K
D
S
R
W
H
L
S
E
D
Site 60
S402
K
D
S
R
W
H
L
S
E
D
E
N
R
S
Y
Site 61
S408
L
S
E
D
E
N
R
S
Y
V
E
I
V
E
D
Site 62
Y409
S
E
D
E
N
R
S
Y
V
E
I
V
E
D
G
Site 63
S428
V
I
Q
Q
V
D
D
S
E
E
E
E
E
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation