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Updated November 2019
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Protein Info
Short Name:
FAM105B
Full Name:
Protein FAM105B
Alias:
Type:
Mass (Da):
40263
Number AA:
352
UniProt ID:
Q96BN8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
P
G
A
S
C
A
E
T
P
A
R
E
A
A
A
Site 2
T28
P
A
R
E
A
A
A
T
A
R
D
G
G
K
A
Site 3
S38
D
G
G
K
A
A
A
S
G
Q
P
R
P
E
M
Site 4
Y56
A
E
H
E
E
D
M
Y
R
A
A
D
E
I
E
Site 5
S76
L
I
H
E
R
G
A
S
E
P
R
L
S
V
A
Site 6
S81
G
A
S
E
P
R
L
S
V
A
P
E
M
D
I
Site 7
Y91
P
E
M
D
I
M
D
Y
C
K
K
E
W
R
G
Site 8
T100
K
K
E
W
R
G
N
T
Q
K
A
T
C
M
K
Site 9
T104
R
G
N
T
Q
K
A
T
C
M
K
M
G
Y
E
Site 10
Y110
A
T
C
M
K
M
G
Y
E
E
V
S
Q
K
F
Site 11
S114
K
M
G
Y
E
E
V
S
Q
K
F
T
S
I
R
Site 12
S119
E
V
S
Q
K
F
T
S
I
R
R
V
R
G
D
Site 13
Y128
R
R
V
R
G
D
N
Y
C
A
L
R
A
T
L
Site 14
S163
L
L
P
E
K
L
I
S
K
Y
N
W
I
K
Q
Site 15
Y165
P
E
K
L
I
S
K
Y
N
W
I
K
Q
W
K
Site 16
T193
D
K
I
K
E
S
L
T
L
L
R
K
K
W
A
Site 17
Y226
F
T
N
E
A
E
E
Y
S
L
Y
E
A
V
K
Site 18
Y229
E
A
E
E
Y
S
L
Y
E
A
V
K
F
L
M
Site 19
Y244
L
N
R
A
I
E
L
Y
N
D
K
E
K
G
K
Site 20
T265
V
L
L
F
A
R
D
T
S
N
D
P
G
Q
L
Site 21
S266
L
L
F
A
R
D
T
S
N
D
P
G
Q
L
L
Site 22
S308
T
I
Q
V
Y
R
L
S
K
Y
N
T
E
E
F
Site 23
Y310
Q
V
Y
R
L
S
K
Y
N
T
E
E
F
I
T
Site 24
T312
Y
R
L
S
K
Y
N
T
E
E
F
I
T
V
Y
Site 25
T317
Y
N
T
E
E
F
I
T
V
Y
P
T
D
P
P
Site 26
Y319
T
E
E
F
I
T
V
Y
P
T
D
P
P
K
D
Site 27
T321
E
F
I
T
V
Y
P
T
D
P
P
K
D
W
P
Site 28
Y340
I
A
E
D
D
R
H
Y
N
I
P
V
R
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation