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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM149B1
Full Name:
Protein FAM149B1
Alias:
Type:
Mass (Da):
64618
Number AA:
582
UniProt ID:
Q96BN6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
T
R
K
A
V
P
Q
S
L
E
L
K
G
I
T
Site 2
S37
P
E
K
L
E
E
I
S
P
T
S
D
S
H
E
Site 3
T39
K
L
E
E
I
S
P
T
S
D
S
H
E
K
D
Site 4
S40
L
E
E
I
S
P
T
S
D
S
H
E
K
D
T
Site 5
S42
E
I
S
P
T
S
D
S
H
E
K
D
T
S
S
Site 6
T47
S
D
S
H
E
K
D
T
S
S
Q
S
K
S
D
Site 7
S48
D
S
H
E
K
D
T
S
S
Q
S
K
S
D
I
Site 8
S49
S
H
E
K
D
T
S
S
Q
S
K
S
D
I
T
Site 9
S51
E
K
D
T
S
S
Q
S
K
S
D
I
T
R
E
Site 10
S53
D
T
S
S
Q
S
K
S
D
I
T
R
E
S
S
Site 11
T56
S
Q
S
K
S
D
I
T
R
E
S
S
F
T
S
Site 12
S59
K
S
D
I
T
R
E
S
S
F
T
S
A
D
T
Site 13
S60
S
D
I
T
R
E
S
S
F
T
S
A
D
T
G
Site 14
T62
I
T
R
E
S
S
F
T
S
A
D
T
G
N
S
Site 15
S63
T
R
E
S
S
F
T
S
A
D
T
G
N
S
L
Site 16
T66
S
S
F
T
S
A
D
T
G
N
S
L
S
A
F
Site 17
S69
T
S
A
D
T
G
N
S
L
S
A
F
P
S
Y
Site 18
S71
A
D
T
G
N
S
L
S
A
F
P
S
Y
T
G
Site 19
S75
N
S
L
S
A
F
P
S
Y
T
G
A
G
I
S
Site 20
S82
S
Y
T
G
A
G
I
S
T
E
G
S
S
D
F
Site 21
S86
A
G
I
S
T
E
G
S
S
D
F
S
W
G
Y
Site 22
S87
G
I
S
T
E
G
S
S
D
F
S
W
G
Y
G
Site 23
S90
T
E
G
S
S
D
F
S
W
G
Y
G
E
L
D
Site 24
Y116
T
A
I
D
E
L
L
Y
E
Q
K
L
S
V
H
Site 25
S121
L
L
Y
E
Q
K
L
S
V
H
T
K
S
L
Q
Site 26
S126
K
L
S
V
H
T
K
S
L
Q
E
E
C
Q
Q
Site 27
T150
I
L
G
R
Q
I
I
T
P
S
E
G
Y
R
L
Site 28
S152
G
R
Q
I
I
T
P
S
E
G
Y
R
L
Y
P
Site 29
Y158
P
S
E
G
Y
R
L
Y
P
R
S
P
S
A
V
Site 30
S161
G
Y
R
L
Y
P
R
S
P
S
A
V
S
A
S
Site 31
S163
R
L
Y
P
R
S
P
S
A
V
S
A
S
Y
E
Site 32
S166
P
R
S
P
S
A
V
S
A
S
Y
E
T
T
L
Site 33
S168
S
P
S
A
V
S
A
S
Y
E
T
T
L
S
Q
Site 34
T172
V
S
A
S
Y
E
T
T
L
S
Q
E
R
D
S
Site 35
S174
A
S
Y
E
T
T
L
S
Q
E
R
D
S
T
I
Site 36
S179
T
L
S
Q
E
R
D
S
T
I
F
G
I
R
G
Site 37
T180
L
S
Q
E
R
D
S
T
I
F
G
I
R
G
K
Site 38
S192
R
G
K
K
L
H
F
S
S
S
Y
A
H
K
A
Site 39
S193
G
K
K
L
H
F
S
S
S
Y
A
H
K
A
S
Site 40
S194
K
K
L
H
F
S
S
S
Y
A
H
K
A
S
S
Site 41
S200
S
S
Y
A
H
K
A
S
S
I
A
K
S
S
S
Site 42
S201
S
Y
A
H
K
A
S
S
I
A
K
S
S
S
F
Site 43
S205
K
A
S
S
I
A
K
S
S
S
F
C
S
M
E
Site 44
S206
A
S
S
I
A
K
S
S
S
F
C
S
M
E
R
Site 45
S207
S
S
I
A
K
S
S
S
F
C
S
M
E
R
D
Site 46
S210
A
K
S
S
S
F
C
S
M
E
R
D
E
E
D
Site 47
S218
M
E
R
D
E
E
D
S
I
I
V
S
E
G
I
Site 48
S222
E
E
D
S
I
I
V
S
E
G
I
I
E
E
Y
Site 49
Y229
S
E
G
I
I
E
E
Y
L
A
F
D
H
I
D
Site 50
S246
E
G
F
H
G
K
K
S
E
A
A
T
E
K
Q
Site 51
T250
G
K
K
S
E
A
A
T
E
K
Q
K
L
G
Y
Site 52
Y257
T
E
K
Q
K
L
G
Y
P
P
I
A
P
F
Y
Site 53
S299
S
H
W
E
G
F
A
S
D
D
E
S
N
V
A
Site 54
S303
G
F
A
S
D
D
E
S
N
V
A
V
T
R
P
Site 55
S312
V
A
V
T
R
P
D
S
E
S
S
C
V
L
S
Site 56
S314
V
T
R
P
D
S
E
S
S
C
V
L
S
E
L
Site 57
S315
T
R
P
D
S
E
S
S
C
V
L
S
E
L
H
Site 58
Y336
V
P
Q
S
K
V
L
Y
I
T
S
N
P
M
S
Site 59
S343
Y
I
T
S
N
P
M
S
L
C
Q
A
S
R
H
Site 60
S370
P
L
Q
P
R
N
L
S
L
M
D
K
L
L
D
Site 61
S388
K
L
L
M
R
P
G
S
S
T
I
L
S
T
R
Site 62
S389
L
L
M
R
P
G
S
S
T
I
L
S
T
R
N
Site 63
T390
L
M
R
P
G
S
S
T
I
L
S
T
R
N
W
Site 64
S393
P
G
S
S
T
I
L
S
T
R
N
W
P
N
R
Site 65
S405
P
N
R
A
V
E
F
S
T
S
S
L
S
Y
T
Site 66
S407
R
A
V
E
F
S
T
S
S
L
S
Y
T
V
Q
Site 67
S408
A
V
E
F
S
T
S
S
L
S
Y
T
V
Q
S
Site 68
S410
E
F
S
T
S
S
L
S
Y
T
V
Q
S
T
R
Site 69
Y411
F
S
T
S
S
L
S
Y
T
V
Q
S
T
R
R
Site 70
T412
S
T
S
S
L
S
Y
T
V
Q
S
T
R
R
R
Site 71
S415
S
L
S
Y
T
V
Q
S
T
R
R
R
N
P
P
Site 72
T416
L
S
Y
T
V
Q
S
T
R
R
R
N
P
P
P
Site 73
T425
R
R
N
P
P
P
R
T
L
H
P
I
S
T
S
Site 74
S430
P
R
T
L
H
P
I
S
T
S
H
S
C
A
E
Site 75
S434
H
P
I
S
T
S
H
S
C
A
E
T
P
R
S
Site 76
T438
T
S
H
S
C
A
E
T
P
R
S
V
E
E
I
Site 77
S441
S
C
A
E
T
P
R
S
V
E
E
I
L
R
G
Site 78
S457
R
V
P
V
A
P
D
S
L
S
S
P
S
P
T
Site 79
S459
P
V
A
P
D
S
L
S
S
P
S
P
T
P
L
Site 80
S460
V
A
P
D
S
L
S
S
P
S
P
T
P
L
S
Site 81
S462
P
D
S
L
S
S
P
S
P
T
P
L
S
R
N
Site 82
T464
S
L
S
S
P
S
P
T
P
L
S
R
N
N
L
Site 83
S467
S
P
S
P
T
P
L
S
R
N
N
L
L
P
P
Site 84
T485
A
E
V
E
H
V
S
T
V
G
P
Q
R
Q
M
Site 85
S498
Q
M
K
P
H
G
D
S
S
R
A
Q
S
A
V
Site 86
S499
M
K
P
H
G
D
S
S
R
A
Q
S
A
V
V
Site 87
S503
G
D
S
S
R
A
Q
S
A
V
V
D
E
P
N
Site 88
Y511
A
V
V
D
E
P
N
Y
Q
Q
P
Q
E
R
L
Site 89
T529
D
F
F
P
R
P
N
T
T
Q
S
F
L
L
D
Site 90
S532
P
R
P
N
T
T
Q
S
F
L
L
D
T
Q
Y
Site 91
T537
T
Q
S
F
L
L
D
T
Q
Y
R
R
S
C
A
Site 92
Y539
S
F
L
L
D
T
Q
Y
R
R
S
C
A
V
E
Site 93
S542
L
D
T
Q
Y
R
R
S
C
A
V
E
Y
P
H
Site 94
Y547
R
R
S
C
A
V
E
Y
P
H
Q
A
R
P
G
Site 95
S557
Q
A
R
P
G
R
G
S
A
G
P
Q
L
H
G
Site 96
S565
A
G
P
Q
L
H
G
S
T
K
S
Q
S
G
G
Site 97
T566
G
P
Q
L
H
G
S
T
K
S
Q
S
G
G
R
Site 98
S568
Q
L
H
G
S
T
K
S
Q
S
G
G
R
P
V
Site 99
S570
H
G
S
T
K
S
Q
S
G
G
R
P
V
S
R
Site 100
S576
Q
S
G
G
R
P
V
S
R
T
R
Q
G
P
_
Site 101
T578
G
G
R
P
V
S
R
T
R
Q
G
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation