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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC17
Full Name:
Tetratricopeptide repeat protein 17
Alias:
FLJ10890; Tetratricopeptide repeat domain 17; TPR repeat protein 17
Type:
Mass (Da):
129560
Number AA:
UniProt ID:
Q96AE7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
A
V
G
V
R
G
R
Y
E
L
P
P
C
S
G
Site 2
S17
R
Y
E
L
P
P
C
S
G
P
G
W
L
L
S
Site 3
S56
K
I
Q
Q
Q
V
D
S
P
M
N
L
K
H
P
Site 4
T101
E
E
N
E
D
R
D
T
G
L
E
Q
R
H
N
Site 5
T130
D
L
D
L
Y
D
G
T
Y
I
T
L
E
S
K
Site 6
Y131
L
D
L
Y
D
G
T
Y
I
T
L
E
S
K
D
Site 7
T133
L
Y
D
G
T
Y
I
T
L
E
S
K
D
I
S
Site 8
S136
G
T
Y
I
T
L
E
S
K
D
I
S
P
E
D
Site 9
S140
T
L
E
S
K
D
I
S
P
E
D
Y
I
D
T
Site 10
Y144
K
D
I
S
P
E
D
Y
I
D
T
E
S
P
V
Site 11
T147
S
P
E
D
Y
I
D
T
E
S
P
V
P
P
D
Site 12
S149
E
D
Y
I
D
T
E
S
P
V
P
P
D
P
E
Site 13
T161
D
P
E
Q
P
D
C
T
K
I
L
E
L
P
Y
Site 14
S186
V
Q
E
R
V
N
L
S
A
P
L
L
P
K
E
Site 15
Y199
K
E
D
P
I
F
T
Y
L
S
K
R
L
G
R
Site 16
S201
D
P
I
F
T
Y
L
S
K
R
L
G
R
S
I
Site 17
S207
L
S
K
R
L
G
R
S
I
D
D
I
G
H
L
Site 18
Y235
L
Y
N
M
A
S
F
Y
W
R
I
K
N
E
P
Site 19
Y243
W
R
I
K
N
E
P
Y
Q
V
V
E
C
A
M
Site 20
S256
A
M
R
A
L
H
F
S
S
R
H
N
K
D
I
Site 21
S292
V
H
A
A
L
D
D
S
D
F
F
T
S
Y
Y
Site 22
T296
L
D
D
S
D
F
F
T
S
Y
Y
T
L
G
N
Site 23
Y298
D
S
D
F
F
T
S
Y
Y
T
L
G
N
I
Y
Site 24
Y299
S
D
F
F
T
S
Y
Y
T
L
G
N
I
Y
A
Site 25
Y305
Y
Y
T
L
G
N
I
Y
A
M
L
G
E
Y
N
Site 26
Y318
Y
N
H
S
V
L
C
Y
D
H
A
L
Q
A
R
Site 27
S354
K
L
E
A
Q
H
R
S
L
Q
R
T
L
N
E
Site 28
T358
Q
H
R
S
L
Q
R
T
L
N
E
L
K
E
Y
Site 29
Y365
T
L
N
E
L
K
E
Y
Q
K
Q
H
D
H
Y
Site 30
Y372
Y
Q
K
Q
H
D
H
Y
L
R
Q
Q
E
I
L
Site 31
Y431
Q
W
D
Q
P
V
R
Y
H
R
G
D
I
F
E
Site 32
Y442
D
I
F
E
N
V
D
Y
V
Q
F
G
E
D
S
Site 33
S449
Y
V
Q
F
G
E
D
S
S
T
S
S
M
M
S
Site 34
S450
V
Q
F
G
E
D
S
S
T
S
S
M
M
S
V
Site 35
T451
Q
F
G
E
D
S
S
T
S
S
M
M
S
V
N
Site 36
S453
G
E
D
S
S
T
S
S
M
M
S
V
N
F
D
Site 37
S456
S
S
T
S
S
M
M
S
V
N
F
D
V
Q
S
Site 38
S463
S
V
N
F
D
V
Q
S
N
Q
S
D
I
N
D
Site 39
S471
N
Q
S
D
I
N
D
S
V
K
S
S
P
V
A
Site 40
S480
K
S
S
P
V
A
H
S
I
L
W
I
W
G
R
Site 41
Y492
W
G
R
D
S
D
A
Y
R
D
K
Q
H
I
L
Site 42
S509
K
R
A
D
C
T
E
S
Y
P
R
V
P
V
G
Site 43
Y510
R
A
D
C
T
E
S
Y
P
R
V
P
V
G
G
Site 44
Y522
V
G
G
E
L
P
T
Y
F
L
P
P
E
N
K
Site 45
S537
G
L
R
I
H
E
L
S
S
D
D
Y
S
T
E
Site 46
S538
L
R
I
H
E
L
S
S
D
D
Y
S
T
E
E
Site 47
Y541
H
E
L
S
S
D
D
Y
S
T
E
E
E
A
Q
Site 48
S542
E
L
S
S
D
D
Y
S
T
E
E
E
A
Q
T
Site 49
T549
S
T
E
E
E
A
Q
T
P
D
C
S
I
T
D
Site 50
S553
E
A
Q
T
P
D
C
S
I
T
D
F
R
K
S
Site 51
T555
Q
T
P
D
C
S
I
T
D
F
R
K
S
H
T
Site 52
S560
S
I
T
D
F
R
K
S
H
T
L
S
Y
L
V
Site 53
S564
F
R
K
S
H
T
L
S
Y
L
V
K
E
L
E
Site 54
Y565
R
K
S
H
T
L
S
Y
L
V
K
E
L
E
V
Site 55
S591
H
A
R
K
I
L
L
S
R
I
N
N
Y
T
I
Site 56
Y596
L
L
S
R
I
N
N
Y
T
I
P
E
E
E
I
Site 57
T597
L
S
R
I
N
N
Y
T
I
P
E
E
E
I
G
Site 58
Y628
I
L
N
E
A
G
L
Y
W
R
A
V
G
N
S
Site 59
T720
R
Q
A
L
K
L
T
T
K
C
P
E
C
E
N
Site 60
T752
T
S
S
V
C
S
G
T
V
V
E
E
S
N
G
Site 61
S760
V
V
E
E
S
N
G
S
D
E
M
E
N
S
D
Site 62
S766
G
S
D
E
M
E
N
S
D
E
T
K
M
S
E
Site 63
T769
E
M
E
N
S
D
E
T
K
M
S
E
E
I
L
Site 64
S772
N
S
D
E
T
K
M
S
E
E
I
L
A
L
V
Site 65
S821
P
Q
D
G
V
A
R
S
S
C
Y
G
D
C
R
Site 66
S822
Q
D
G
V
A
R
S
S
C
Y
G
D
C
R
S
Site 67
S829
S
C
Y
G
D
C
R
S
E
D
D
E
A
T
E
Site 68
T835
R
S
E
D
D
E
A
T
E
W
I
T
F
Q
V
Site 69
T839
D
E
A
T
E
W
I
T
F
Q
V
K
R
V
K
Site 70
T855
P
K
G
D
H
K
K
T
P
G
K
K
V
E
T
Site 71
Y871
Q
I
E
N
G
H
R
Y
Q
A
N
L
E
I
T
Site 72
S884
I
T
G
P
K
V
A
S
P
G
P
Q
G
K
K
Site 73
Y894
P
Q
G
K
K
R
D
Y
Q
R
L
G
W
P
S
Site 74
S901
Y
Q
R
L
G
W
P
S
P
D
E
C
L
K
L
Site 75
T931
S
S
K
N
I
D
I
T
E
H
I
D
F
A
T
Site 76
T938
T
E
H
I
D
F
A
T
P
I
Q
Q
P
A
M
Site 77
S967
L
D
H
L
H
G
V
S
N
R
A
S
L
H
Y
Site 78
S971
H
G
V
S
N
R
A
S
L
H
Y
T
G
E
S
Site 79
Y974
S
N
R
A
S
L
H
Y
T
G
E
S
Q
L
T
Site 80
T975
N
R
A
S
L
H
Y
T
G
E
S
Q
L
T
E
Site 81
T981
Y
T
G
E
S
Q
L
T
E
V
L
Q
N
L
G
Site 82
Y992
Q
N
L
G
K
D
Q
Y
P
Q
Q
S
L
E
Q
Site 83
T1013
K
V
L
E
K
N
Q
T
S
W
V
L
S
S
M
Site 84
S1014
V
L
E
K
N
Q
T
S
W
V
L
S
S
M
A
Site 85
Y1024
L
S
S
M
A
A
L
Y
W
R
V
K
G
Q
G
Site 86
Y1044
C
L
R
Q
A
L
H
Y
A
P
H
Q
M
K
D
Site 87
Y1108
F
E
K
A
L
V
W
Y
E
S
T
L
K
L
Q
Site 88
S1110
K
A
L
V
W
Y
E
S
T
L
K
L
Q
P
E
Site 89
T1127
P
A
K
N
R
I
Q
T
I
Q
C
H
L
M
L
Site 90
S1140
M
L
K
K
G
R
R
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation