PhosphoNET

           
Protein Info 
   
Short Name:  islet-2
Full Name:  Insulin gene enhancer protein ISL-2
Alias:  FLJ10160; ISL LIM homeobox 2; ISL2
Type: 
Mass (Da):  39768
Number AA:  359
UniProt ID:  Q96A47
International Prot ID:  IPI00059240
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18LGAMGDHSKKKPGTA
Site 2T24HSKKKPGTAMCVGCG
Site 3S43DQFILRVSPDLEWHA
Site 4Y61KCAECSQYLDETCTC
Site 5Y76FVRDGKTYCKRDYVR
Site 6Y81KTYCKRDYVRLFGIK
Site 7S99CQVGFSSSDLVMRAR
Site 8Y110MRARDSVYHIECFRC
Site 9S131LLPGDEFSLREHELL
Site 10S154LERAAAGSPRSPGPL
Site 11S157AAAGSPRSPGPLPGA
Site 12S174LHLPDAGSGRQPALR
Site 13T191VHKQTEKTTRVRTVL
Site 14T196EKTTRVRTVLNEKQL
Site 15Y210LHTLRTCYAANPRPD
Site 16S250RCKDKKKSILMKQLQ
Site 17S262QLQQQQHSDKTSLQG
Site 18T265QQQHSDKTSLQGLTG
Site 19S266QQHSDKTSLQGLTGT
Site 20S279GTPLVAGSPIRHENA
Site 21Y297SAVEVQTYQPPWKAL
Site 22S305QPPWKALSEFALQSD
Site 23S311LSEFALQSDLDQPAF
Site 24S323PAFQQLVSFSESGSL
Site 25S325FQQLVSFSESGSLGN
Site 26S327QLVSFSESGSLGNSS
Site 27S329VSFSESGSLGNSSGS
Site 28S333ESGSLGNSSGSDVTS
Site 29S334SGSLGNSSGSDVTSL
Site 30S336SLGNSSGSDVTSLSS
Site 31T339NSSGSDVTSLSSQLP
Site 32S340SSGSDVTSLSSQLPD
Site 33S342GSDVTSLSSQLPDTP
Site 34S343SDVTSLSSQLPDTPN
Site 35T348LSSQLPDTPNSMVPS
Site 36S351QLPDTPNSMVPSPVE
Site 37S355TPNSMVPSPVET___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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