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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFM2
Full Name:
Ribosome-releasing factor 2, mitochondrial
Alias:
Elongation factor G 2, mitochondrial;Elongation factor G2
Type:
Mass (Da):
86601
Number AA:
779
UniProt ID:
Q969S9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
N
L
R
I
F
A
M
S
H
Q
T
I
P
S
V
Site 2
T14
I
F
A
M
S
H
Q
T
I
P
S
V
Y
I
N
Site 3
S31
C
C
Y
K
I
R
A
S
L
K
R
L
K
P
H
Site 4
S47
P
L
G
R
N
C
S
S
L
P
G
L
I
G
N
Site 5
T86
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
Site 6
T87
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
S
Site 7
Y92
T
T
T
E
R
I
L
Y
Y
S
G
Y
T
R
S
Site 8
S94
T
E
R
I
L
Y
Y
S
G
Y
T
R
S
L
G
Site 9
Y96
R
I
L
Y
Y
S
G
Y
T
R
S
L
G
D
V
Site 10
S99
Y
Y
S
G
Y
T
R
S
L
G
D
V
D
D
G
Site 11
T108
G
D
V
D
D
G
D
T
V
T
D
F
M
A
Q
Site 12
T110
V
D
D
G
D
T
V
T
D
F
M
A
Q
E
R
Site 13
T122
Q
E
R
E
R
G
I
T
I
Q
S
A
A
V
T
Site 14
T129
T
I
Q
S
A
A
V
T
F
D
W
K
G
Y
R
Site 15
T142
Y
R
V
N
L
I
D
T
P
G
H
V
D
F
T
Site 16
T149
T
P
G
H
V
D
F
T
L
E
V
E
R
C
L
Site 17
T178
G
V
E
A
Q
T
L
T
V
W
R
Q
A
D
K
Site 18
T200
F
L
N
K
M
D
K
T
G
A
S
F
K
Y
A
Site 19
S203
K
M
D
K
T
G
A
S
F
K
Y
A
V
E
S
Site 20
Y206
K
T
G
A
S
F
K
Y
A
V
E
S
I
R
E
Site 21
S210
S
F
K
Y
A
V
E
S
I
R
E
K
L
K
A
Site 22
T346
Q
P
L
L
D
A
V
T
M
Y
L
P
S
P
E
Site 23
Y348
L
L
D
A
V
T
M
Y
L
P
S
P
E
E
R
Site 24
S351
A
V
T
M
Y
L
P
S
P
E
E
R
N
Y
E
Site 25
Y357
P
S
P
E
E
R
N
Y
E
F
L
Q
W
Y
K
Site 26
Y363
N
Y
E
F
L
Q
W
Y
K
D
D
L
C
A
L
Site 27
T407
H
N
I
N
G
N
C
T
E
R
I
S
R
L
L
Site 28
S426
D
Q
H
V
E
I
P
S
L
T
A
G
N
I
A
Site 29
T446
K
H
T
A
T
G
D
T
I
V
S
S
K
S
S
Site 30
S453
T
I
V
S
S
K
S
S
A
L
A
A
A
R
R
Site 31
S498
F
C
T
I
E
P
P
S
L
S
K
Q
P
D
L
Site 32
S500
T
I
E
P
P
S
L
S
K
Q
P
D
L
E
H
Site 33
S518
C
L
Q
R
E
D
P
S
L
K
V
R
L
D
P
Site 34
S527
K
V
R
L
D
P
D
S
G
Q
T
V
L
C
G
Site 35
T530
L
D
P
D
S
G
Q
T
V
L
C
G
M
G
E
Site 36
Y551
H
D
R
I
K
R
E
Y
G
L
E
T
Y
L
G
Site 37
Y556
R
E
Y
G
L
E
T
Y
L
G
P
L
Q
V
A
Site 38
Y564
L
G
P
L
Q
V
A
Y
R
E
T
I
L
N
S
Site 39
S571
Y
R
E
T
I
L
N
S
V
R
A
T
D
T
L
Site 40
T575
I
L
N
S
V
R
A
T
D
T
L
D
R
T
L
Site 41
T577
N
S
V
R
A
T
D
T
L
D
R
T
L
G
D
Site 42
T581
A
T
D
T
L
D
R
T
L
G
D
K
R
H
L
Site 43
T590
G
D
K
R
H
L
V
T
V
E
V
E
A
R
P
Site 44
S601
E
A
R
P
I
E
T
S
S
V
M
P
V
I
E
Site 45
S614
I
E
F
E
Y
A
E
S
I
N
E
G
L
L
K
Site 46
T745
G
Y
S
T
V
L
R
T
L
T
S
G
S
A
T
Site 47
Y760
F
A
L
E
L
S
T
Y
Q
A
M
N
P
Q
D
Site 48
T770
M
N
P
Q
D
Q
N
T
L
L
N
R
R
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation