PhosphoNET

           
Protein Info 
   
Short Name:  NEIL2
Full Name:  Endonuclease 8-like 2
Alias:  DNA glycosylase/AP lyase Neil2;DNA-(apurinic or apyrimidinic site) lyase Neil2;Endonuclease VIII-like 2;Nei homolog 2;Nei-like protein 2
Type: 
Mass (Da):  36826
Number AA:  332
UniProt ID:  Q969S2
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S15RKFHHLVSPFVGQQV
Site 2T25VGQQVVKTGGSSKKL
Site 3S36SKKLQPASLQSLWLQ
Site 4S39LQPASLQSLWLQDTQ
Site 5T45QSLWLQDTQVHGKKL
Site 6S67EEMGPPGSSPTPEPP
Site 7S68EMGPPGSSPTPEPPQ
Site 8T70GPPGSSPTPEPPQKE
Site 9S93PKQVGEPSGQKTLDG
Site 10T97GEPSGQKTLDGSSRS
Site 11S102QKTLDGSSRSAELVP
Site 12S104TLDGSSRSAELVPQG
Site 13S115VPQGEDDSEYLERDA
Site 14Y117QGEDDSEYLERDAPA
Site 15S147SVWVNDFSRAKKANK
Site 16S162RGDWRDPSPRLVLHF
Site 17S185YNCQLSWSSSPVVTP
Site 18T193SSPVVTPTCDILSEK
Site 19S198TPTCDILSEKFHRGQ
Site 20Y225YTLLDQRYFSGLGNI
Site 21S323PQCQPQLSEEPEQCQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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