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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP2R3C
Full Name:
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Alias:
Protein phosphatase subunit G5PR;Rhabdomyosarcoma antigen MU-RMS-40.6A/6C
Type:
Mass (Da):
53316
Number AA:
453
UniProt ID:
Q969Q6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
V
L
R
R
R
L
A
T
P
N
T
C
P
N
K
Site 2
T16
R
R
L
A
T
P
N
T
C
P
N
K
K
K
S
Site 3
Y38
E
M
D
L
F
T
K
Y
Y
S
E
W
K
G
G
Site 4
Y39
M
D
L
F
T
K
Y
Y
S
E
W
K
G
G
R
Site 5
T49
W
K
G
G
R
K
N
T
N
E
F
Y
K
T
I
Site 6
Y60
Y
K
T
I
P
R
F
Y
Y
R
L
P
A
E
D
Site 7
Y61
K
T
I
P
R
F
Y
Y
R
L
P
A
E
D
E
Site 8
S78
L
Q
K
L
R
E
E
S
R
A
V
F
L
Q
R
Site 9
S87
A
V
F
L
Q
R
K
S
R
E
L
L
D
N
E
Site 10
T108
F
L
L
D
K
H
Q
T
P
P
M
I
G
E
E
Site 11
Y120
G
E
E
A
M
I
N
Y
E
N
F
L
K
V
G
Site 12
S151
A
K
L
L
H
T
D
S
Y
G
R
I
S
I
M
Site 13
Y152
K
L
L
H
T
D
S
Y
G
R
I
S
I
M
Q
Site 14
T173
R
K
V
W
L
H
Q
T
R
I
G
L
S
L
Y
Site 15
S178
H
Q
T
R
I
G
L
S
L
Y
D
V
A
G
Q
Site 16
Y180
T
R
I
G
L
S
L
Y
D
V
A
G
Q
G
Y
Site 17
Y187
Y
D
V
A
G
Q
G
Y
L
R
E
S
D
L
E
Site 18
S191
G
Q
G
Y
L
R
E
S
D
L
E
N
Y
I
L
Site 19
Y215
D
G
L
E
K
S
F
Y
S
F
Y
V
C
T
A
Site 20
Y218
E
K
S
F
Y
S
F
Y
V
C
T
A
V
R
K
Site 21
S261
E
L
R
D
E
E
L
S
K
E
S
Q
E
T
N
Site 22
T267
L
S
K
E
S
Q
E
T
N
W
F
S
A
P
S
Site 23
S271
S
Q
E
T
N
W
F
S
A
P
S
A
L
R
V
Site 24
Y279
A
P
S
A
L
R
V
Y
G
Q
Y
L
N
L
D
Site 25
Y282
A
L
R
V
Y
G
Q
Y
L
N
L
D
K
D
H
Site 26
S294
K
D
H
N
G
M
L
S
K
E
E
L
S
R
Y
Site 27
Y301
S
K
E
E
L
S
R
Y
G
T
A
T
M
T
N
Site 28
T303
E
E
L
S
R
Y
G
T
A
T
M
T
N
V
F
Site 29
Y321
V
F
Q
E
C
L
T
Y
D
G
E
M
D
Y
K
Site 30
Y327
T
Y
D
G
E
M
D
Y
K
T
Y
L
D
F
V
Site 31
T329
D
G
E
M
D
Y
K
T
Y
L
D
F
V
L
A
Site 32
Y360
L
D
I
E
N
K
G
Y
L
N
V
F
S
L
N
Site 33
S386
I
H
G
Q
D
P
V
S
F
Q
D
V
K
D
E
Site 34
S407
P
K
D
P
L
K
I
S
L
Q
D
L
I
N
S
Site 35
T419
I
N
S
N
Q
G
D
T
V
T
T
I
L
I
D
Site 36
Y433
D
L
N
G
F
W
T
Y
E
N
R
E
A
L
V
Site 37
S444
E
A
L
V
A
N
D
S
E
N
S
A
D
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation