KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TRIM63
Full Name:
E3 ubiquitin-protein ligase TRIM63
Alias:
Iris RING finger protein;Muscle-specific RING finger protein 1;RING finger protein 28;Striated muscle RING zinc finger protein;Tripartite motif-containing protein 63
Type:
Mass (Da):
40248
Number AA:
353
UniProt ID:
Q969Q1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y58
I
F
Q
A
A
N
P
Y
W
T
S
R
G
S
S
Site 2
T60
Q
A
A
N
P
Y
W
T
S
R
G
S
S
V
S
Site 3
S61
A
A
N
P
Y
W
T
S
R
G
S
S
V
S
M
Site 4
S64
P
Y
W
T
S
R
G
S
S
V
S
M
S
G
G
Site 5
S65
Y
W
T
S
R
G
S
S
V
S
M
S
G
G
R
Site 6
S67
T
S
R
G
S
S
V
S
M
S
G
G
R
F
R
Site 7
S69
R
G
S
S
V
S
M
S
G
G
R
F
R
C
P
Site 8
Y105
V
E
N
I
I
D
I
Y
K
Q
E
C
S
S
R
Site 9
S110
D
I
Y
K
Q
E
C
S
S
R
P
L
Q
K
G
Site 10
T168
S
V
F
Q
G
Q
K
T
E
L
N
N
C
I
S
Site 11
T186
A
G
N
D
R
V
Q
T
I
I
T
Q
L
E
D
Site 12
S194
I
I
T
Q
L
E
D
S
R
R
V
T
K
E
N
Site 13
T198
L
E
D
S
R
R
V
T
K
E
N
S
H
Q
V
Site 14
S210
H
Q
V
K
E
E
L
S
Q
K
F
D
T
L
Y
Site 15
T215
E
L
S
Q
K
F
D
T
L
Y
A
I
L
D
E
Site 16
Y217
S
Q
K
F
D
T
L
Y
A
I
L
D
E
K
K
Site 17
S225
A
I
L
D
E
K
K
S
E
L
L
Q
R
I
T
Site 18
T232
S
E
L
L
Q
R
I
T
Q
E
Q
E
K
K
L
Site 19
S240
Q
E
Q
E
K
K
L
S
F
I
E
A
L
I
Q
Site 20
S285
T
A
K
Q
L
I
K
S
I
V
E
A
S
K
G
Site 21
T298
K
G
C
Q
L
G
K
T
E
Q
G
F
E
N
M
Site 22
T326
L
R
A
I
D
F
G
T
D
E
E
E
E
E
F
Site 23
S344
E
D
Q
E
E
E
E
S
T
E
G
K
E
E
G
Site 24
T345
D
Q
E
E
E
E
S
T
E
G
K
E
E
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation