PhosphoNET

           
Protein Info 
   
Short Name:  RNF34
Full Name:  E3 ubiquitin-protein ligase RNF34
Alias:  CARP-1; Caspase regulator CARP1; Caspases-8 and -10-associated RING finger protein 1; EC 6.3.2.-; FYVE-RING finger protein Momo; RFI; RIF; RIFF; RING finger homologous to inhibitor of apoptosis protein; RING finger prote
Type:  Regulatory protein, protease inhibitor. Targets caspases for degradation.
Mass (Da):  41641
Number AA:  372
UniProt ID:  Q969K3
International Prot ID:  IPI00100010
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0019898  GO:0016607  GO:0016020 Uniprot OncoNet
Molecular Function:  GO:0016874  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0019941  GO:0006915 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T22LLNEVMGTGAVRGQQ
Site 2T42ATGPFRFTPNPEFST
Site 3S48FTPNPEFSTYPPAAT
Site 4Y50PNPEFSTYPPAATEG
Site 5T55STYPPAATEGPNIVC
Site 6S70KACGLSFSVFRKKHV
Site 7S90KDFCSVCSVLQENLR
Site 8S100QENLRRCSTCHLLQE
Site 9T101ENLRRCSTCHLLQET
Site 10Y126KVKDLRQYLILRNIP
Site 11T136LRNIPIDTCREKEDL
Site 12S155LCHHGLGSEDDMDTS
Site 13T161GSEDDMDTSSLNSSR
Site 14S162SEDDMDTSSLNSSRS
Site 15S163EDDMDTSSLNSSRSQ
Site 16S166MDTSSLNSSRSQTSS
Site 17S167DTSSLNSSRSQTSSF
Site 18S169SSLNSSRSQTSSFFT
Site 19T171LNSSRSQTSSFFTRS
Site 20S173SSRSQTSSFFTRSFF
Site 21T176SQTSSFFTRSFFSNY
Site 22S178TSSFFTRSFFSNYTA
Site 23Y183TRSFFSNYTAPSATM
Site 24S187FSNYTAPSATMSSFQ
Site 25S191TAPSATMSSFQGELM
Site 26S192APSATMSSFQGELMD
Site 27T203ELMDGDQTSRSGVPA
Site 28S204LMDGDQTSRSGVPAQ
Site 29S206DGDQTSRSGVPAQVQ
Site 30S218QVQSEITSANTEDDD
Site 31S247EDRNPGLSKERVRAS
Site 32S254SKERVRASLSDLSSL
Site 33S256ERVRASLSDLSSLDD
Site 34S260ASLSDLSSLDDVEGM
Site 35S268LDDVEGMSVRQLKEI
Site 36Y283LARNFVNYSGCCEKW
Site 37Y300VEKVNRLYKENEENQ
Site 38S309ENEENQKSYGERLQL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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