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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP6V0A1
Full Name:
V-type proton ATPase 116 kDa subunit a isoform 1
Alias:
Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa; H(+)-transporting two-sector ATPase, 116 kDa accessory A1; Stv1; Vacuolar adenosine triphosphatase Ac116; Vacuolar proton pump 1; Vacuolar proton pump, subunit 1; Vacuolar proton translocating ATPase 116 kDa a isoform 1; Vacuolar-type H(+)-ATPase 115 kDa subunit; V-ATPase 116-kDa a1; Vph1; VPP1
Type:
Energy Metabolism - oxidative phosphorylation; Transporter
Mass (Da):
96413
Number AA:
837
UniProt ID:
Q93050
International Prot ID:
IPI00743576
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0042470
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0051117
GO:0015078
PhosphoSite+
KinaseNET
Biological Process:
GO:0015986
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
E
L
F
R
S
E
E
M
T
L
A
Q
Site 2
T126
K
R
N
F
L
E
L
T
E
L
K
F
I
L
R
Site 3
T135
L
K
F
I
L
R
K
T
Q
Q
F
F
D
E
M
Site 4
S152
P
D
L
L
E
E
S
S
S
L
L
E
P
S
E
Site 5
S153
D
L
L
E
E
S
S
S
L
L
E
P
S
E
M
Site 6
S158
S
S
S
L
L
E
P
S
E
M
G
R
G
T
P
Site 7
T164
P
S
E
M
G
R
G
T
P
L
R
L
G
F
V
Site 8
T182
I
N
R
E
R
I
P
T
F
E
R
M
L
W
R
Site 9
T211
N
P
L
E
D
P
V
T
G
D
Y
V
H
K
S
Site 10
Y214
E
D
P
V
T
G
D
Y
V
H
K
S
V
F
I
Site 11
S243
I
C
E
G
F
R
A
S
L
Y
P
C
P
E
T
Site 12
Y245
E
G
F
R
A
S
L
Y
P
C
P
E
T
P
Q
Site 13
T250
S
L
Y
P
C
P
E
T
P
Q
E
R
K
E
M
Site 14
S259
Q
E
R
K
E
M
A
S
G
V
N
T
R
I
D
Site 15
T263
E
M
A
S
G
V
N
T
R
I
D
D
L
Q
M
Site 16
Y304
V
R
K
M
K
A
I
Y
H
T
L
N
L
C
N
Site 17
S332
C
P
V
T
D
L
D
S
I
Q
F
A
L
R
R
Site 18
T341
Q
F
A
L
R
R
G
T
E
H
S
G
S
T
V
Site 19
S344
L
R
R
G
T
E
H
S
G
S
T
V
P
S
I
Site 20
S346
R
G
T
E
H
S
G
S
T
V
P
S
I
L
N
Site 21
T347
G
T
E
H
S
G
S
T
V
P
S
I
L
N
R
Site 22
S350
H
S
G
S
T
V
P
S
I
L
N
R
M
Q
T
Site 23
T357
S
I
L
N
R
M
Q
T
N
Q
T
P
P
T
Y
Site 24
T360
N
R
M
Q
T
N
Q
T
P
P
T
Y
N
K
T
Site 25
T363
Q
T
N
Q
T
P
P
T
Y
N
K
T
N
K
F
Site 26
Y364
T
N
Q
T
P
P
T
Y
N
K
T
N
K
F
T
Site 27
Y381
F
Q
N
I
V
D
A
Y
G
I
G
T
Y
R
E
Site 28
S428
V
W
M
V
L
R
E
S
R
I
L
S
Q
K
N
Site 29
S432
L
R
E
S
R
I
L
S
Q
K
N
E
N
E
M
Site 30
S441
K
N
E
N
E
M
F
S
T
V
F
S
G
R
Y
Site 31
T442
N
E
N
E
M
F
S
T
V
F
S
G
R
Y
I
Site 32
Y464
S
M
Y
T
G
L
I
Y
N
D
C
F
S
K
S
Site 33
S471
Y
N
D
C
F
S
K
S
L
N
I
F
G
S
S
Site 34
S477
K
S
L
N
I
F
G
S
S
W
S
V
R
P
M
Site 35
Y487
S
V
R
P
M
F
T
Y
N
W
T
E
E
T
L
Site 36
T493
T
Y
N
W
T
E
E
T
L
R
G
N
P
V
L
Site 37
T530
N
I
A
T
N
K
L
T
F
L
N
S
F
K
M
Site 38
S534
N
K
L
T
F
L
N
S
F
K
M
K
M
S
V
Site 39
Y597
I
F
Y
K
W
T
A
Y
D
A
H
T
S
E
N
Site 40
S607
H
T
S
E
N
A
P
S
L
L
I
H
F
I
N
Site 41
S623
F
L
F
S
Y
P
E
S
G
Y
S
M
L
Y
S
Site 42
S626
S
Y
P
E
S
G
Y
S
M
L
Y
S
G
Q
K
Site 43
Y629
E
S
G
Y
S
M
L
Y
S
G
Q
K
G
I
Q
Site 44
S630
S
G
Y
S
M
L
Y
S
G
Q
K
G
I
Q
C
Site 45
Y662
P
L
V
L
R
R
Q
Y
L
R
R
K
H
L
G
Site 46
T670
L
R
R
K
H
L
G
T
L
N
F
G
G
I
R
Site 47
S696
I
I
Q
H
D
Q
L
S
T
H
S
E
D
A
D
Site 48
S706
S
E
D
A
D
E
P
S
E
D
E
V
F
D
F
Site 49
S816
E
F
Q
N
K
F
Y
S
G
T
G
F
K
F
L
Site 50
S826
G
F
K
F
L
P
F
S
F
E
H
I
R
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation