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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COPS5
Full Name:
COP9 signalosome complex subunit 5
Alias:
38 kDa Mov34; COP9 constitutive photomorphogenic subunit 5; COP9 signalosome complex 5; CSN5; JAB1; Jun activation domain-binding; Jun activation domain-binding 1; MOV-34; SGN5; signalosome 5
Type:
EC 3.4.-.-; Adaptor/scaffold; Protease; Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Translation
Mass (Da):
37579
Number AA:
334
UniProt ID:
Q92905
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005852
GO:0008180
Uniprot
OncoNet
Molecular Function:
GO:0046872
GO:0008237
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0000338
GO:0006366
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
G
S
G
M
A
Q
K
T
W
E
L
A
N
N
M
Site 2
Y29
A
Q
S
I
D
E
I
Y
K
Y
D
K
K
Q
Q
Site 3
Y31
S
I
D
E
I
Y
K
Y
D
K
K
Q
Q
Q
E
Site 4
Y54
K
D
H
H
Y
F
K
Y
C
K
I
S
A
L
A
Site 5
T105
L
P
V
E
G
T
E
T
R
V
N
A
Q
A
A
Site 6
Y137
L
E
N
A
I
G
W
Y
H
S
H
P
G
Y
G
Site 7
S148
P
G
Y
G
C
W
L
S
G
I
D
V
S
T
Q
Site 8
T154
L
S
G
I
D
V
S
T
Q
M
L
N
Q
Q
F
Site 9
S177
I
D
P
T
R
T
I
S
A
G
K
V
N
L
G
Site 10
Y189
N
L
G
A
F
R
T
Y
P
K
G
Y
K
P
P
Site 11
Y193
F
R
T
Y
P
K
G
Y
K
P
P
D
E
G
P
Site 12
Y203
P
D
E
G
P
S
E
Y
Q
T
I
P
L
N
K
Site 13
T205
E
G
P
S
E
Y
Q
T
I
P
L
N
K
I
E
Site 14
Y221
F
G
V
H
C
K
Q
Y
Y
A
L
E
V
S
Y
Site 15
Y222
G
V
H
C
K
Q
Y
Y
A
L
E
V
S
Y
F
Site 16
S227
Q
Y
Y
A
L
E
V
S
Y
F
K
S
S
L
D
Site 17
Y228
Y
Y
A
L
E
V
S
Y
F
K
S
S
L
D
R
Site 18
S231
L
E
V
S
Y
F
K
S
S
L
D
R
K
L
L
Site 19
S232
E
V
S
Y
F
K
S
S
L
D
R
K
L
L
E
Site 20
Y245
L
E
L
L
W
N
K
Y
W
V
N
T
L
S
S
Site 21
T249
W
N
K
Y
W
V
N
T
L
S
S
S
S
L
L
Site 22
S251
K
Y
W
V
N
T
L
S
S
S
S
L
L
T
N
Site 23
S252
Y
W
V
N
T
L
S
S
S
S
L
L
T
N
A
Site 24
T257
L
S
S
S
S
L
L
T
N
A
D
Y
T
T
G
Site 25
Y261
S
L
L
T
N
A
D
Y
T
T
G
Q
V
F
D
Site 26
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Site 27
S276
L
S
E
K
L
E
Q
S
E
A
Q
L
G
R
G
Site 28
S284
E
A
Q
L
G
R
G
S
F
M
L
G
L
E
T
Site 29
T291
S
F
M
L
G
L
E
T
H
D
R
K
S
E
D
Site 30
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Site 31
T304
E
D
K
L
A
K
A
T
R
D
S
C
K
T
T
Site 32
S307
L
A
K
A
T
R
D
S
C
K
T
T
I
E
A
Site 33
T310
A
T
R
D
S
C
K
T
T
I
E
A
I
H
G
Site 34
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation