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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATOH1
Full Name:
Protein atonal homolog 1
Alias:
Class A basic helix-loop-helix protein 14;Helix-loop-helix protein hATH-1
Type:
Mass (Da):
38160
Number AA:
354
UniProt ID:
Q92858
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T40
P
P
P
Q
P
P
A
T
L
Q
A
R
E
H
P
Site 2
Y49
Q
A
R
E
H
P
V
Y
P
P
E
L
S
L
L
Site 3
S54
P
V
Y
P
P
E
L
S
L
L
D
S
T
D
P
Site 4
S58
P
E
L
S
L
L
D
S
T
D
P
R
A
W
L
Site 5
T59
E
L
S
L
L
D
S
T
D
P
R
A
W
L
A
Site 6
Y80
C
T
A
R
A
A
Q
Y
L
L
H
S
P
E
L
Site 7
S84
A
A
Q
Y
L
L
H
S
P
E
L
G
A
S
E
Site 8
S90
H
S
P
E
L
G
A
S
E
A
A
A
P
R
D
Site 9
S109
R
G
E
L
V
R
R
S
S
G
G
A
S
S
S
Site 10
S110
G
E
L
V
R
R
S
S
G
G
A
S
S
S
K
Site 11
S114
R
R
S
S
G
G
A
S
S
S
K
S
P
G
P
Site 12
S115
R
S
S
G
G
A
S
S
S
K
S
P
G
P
V
Site 13
S116
S
S
G
G
A
S
S
S
K
S
P
G
P
V
K
Site 14
S118
G
G
A
S
S
S
K
S
P
G
P
V
K
V
R
Site 15
S143
V
V
D
E
L
G
C
S
R
Q
R
A
P
S
S
Site 16
S149
C
S
R
Q
R
A
P
S
S
K
Q
V
N
G
V
Site 17
S150
S
R
Q
R
A
P
S
S
K
Q
V
N
G
V
Q
Site 18
S188
Q
L
R
N
V
I
P
S
F
N
N
D
K
K
L
Site 19
Y198
N
D
K
K
L
S
K
Y
E
T
L
Q
M
A
Q
Site 20
T200
K
K
L
S
K
Y
E
T
L
Q
M
A
Q
I
Y
Site 21
T217
A
L
S
E
L
L
Q
T
P
S
G
G
E
Q
P
Site 22
S219
S
E
L
L
Q
T
P
S
G
G
E
Q
P
P
P
Site 23
S230
Q
P
P
P
P
P
A
S
C
K
S
D
H
H
H
Site 24
S233
P
P
P
A
S
C
K
S
D
H
H
H
L
R
T
Site 25
S243
H
H
L
R
T
A
A
S
Y
E
G
G
A
G
N
Site 26
Y244
H
L
R
T
A
A
S
Y
E
G
G
A
G
N
A
Site 27
S263
A
Q
Q
A
S
G
G
S
Q
R
P
T
P
P
G
Site 28
T267
S
G
G
S
Q
R
P
T
P
P
G
S
C
R
T
Site 29
S271
Q
R
P
T
P
P
G
S
C
R
T
R
F
S
A
Site 30
S277
G
S
C
R
T
R
F
S
A
P
A
S
A
G
G
Site 31
S281
T
R
F
S
A
P
A
S
A
G
G
Y
S
V
Q
Site 32
S286
P
A
S
A
G
G
Y
S
V
Q
L
D
A
L
H
Site 33
S312
M
M
A
Q
K
N
L
S
P
S
L
P
G
S
I
Site 34
S314
A
Q
K
N
L
S
P
S
L
P
G
S
I
L
Q
Site 35
S318
L
S
P
S
L
P
G
S
I
L
Q
P
V
Q
E
Site 36
S328
Q
P
V
Q
E
E
N
S
K
T
S
P
R
S
H
Site 37
T330
V
Q
E
E
N
S
K
T
S
P
R
S
H
R
S
Site 38
S331
Q
E
E
N
S
K
T
S
P
R
S
H
R
S
D
Site 39
S334
N
S
K
T
S
P
R
S
H
R
S
D
G
E
F
Site 40
S337
T
S
P
R
S
H
R
S
D
G
E
F
S
P
H
Site 41
S342
H
R
S
D
G
E
F
S
P
H
S
H
Y
S
D
Site 42
S345
D
G
E
F
S
P
H
S
H
Y
S
D
S
D
E
Site 43
S348
F
S
P
H
S
H
Y
S
D
S
D
E
A
S
_
Site 44
S350
P
H
S
H
Y
S
D
S
D
E
A
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation