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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIFAP3
Full Name:
Kinesin-associated protein 3
Alias:
,RP1-190I16.1-001; KAP3; KIFA3; OTTHUMP00000060402; SMAP; Smg GDS; Smg GDS-associated protein
Type:
Adaptor/scaffold
Mass (Da):
91205
Number AA:
792
UniProt ID:
Q92845
International Prot ID:
IPI00386442
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016939
GO:0005875
Uniprot
OncoNet
Molecular Function:
GO:0019894
GO:0005515
GO:0008092
PhosphoSite+
KinaseNET
Biological Process:
GO:0007017
GO:0006461
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
Q
G
E
D
A
R
Y
L
K
R
K
V
K
G
Site 2
Y31
E
K
A
L
I
V
H
Y
E
V
E
A
T
I
L
Site 3
T36
V
H
Y
E
V
E
A
T
I
L
G
E
M
G
D
Site 4
S60
Q
K
I
I
R
L
K
S
L
N
A
N
T
D
I
Site 5
S69
N
A
N
T
D
I
T
S
L
A
R
K
V
V
E
Site 6
Y94
N
E
V
E
Q
L
L
Y
Y
L
Q
N
R
R
D
Site 7
Y95
E
V
E
Q
L
L
Y
Y
L
Q
N
R
R
D
S
Site 8
S102
Y
L
Q
N
R
R
D
S
L
S
G
K
E
K
K
Site 9
S104
Q
N
R
R
D
S
L
S
G
K
E
K
K
E
K
Site 10
S112
G
K
E
K
K
E
K
S
S
K
P
K
D
P
P
Site 11
S113
K
E
K
K
E
K
S
S
K
P
K
D
P
P
P
Site 12
Y138
N
I
N
D
M
D
E
Y
I
E
L
L
Y
E
D
Site 13
Y143
D
E
Y
I
E
L
L
Y
E
D
I
P
D
K
V
Site 14
T256
D
E
D
P
E
N
Q
T
L
R
K
D
Y
E
K
Site 15
Y261
N
Q
T
L
R
K
D
Y
E
K
T
F
K
K
Y
Site 16
T264
L
R
K
D
Y
E
K
T
F
K
K
Y
Q
G
L
Site 17
Y268
Y
E
K
T
F
K
K
Y
Q
G
L
V
V
K
Q
Site 18
Y284
Q
L
L
R
V
A
L
Y
L
L
L
N
L
A
E
Site 19
T295
N
L
A
E
D
T
R
T
E
L
K
M
R
N
K
Site 20
Y422
R
F
K
S
M
F
A
Y
T
D
C
I
P
Q
L
Site 21
S437
M
K
M
L
F
E
C
S
D
E
R
I
D
L
E
Site 22
S491
M
K
M
I
R
N
I
S
Q
H
D
G
P
T
K
Site 23
S513
G
D
L
A
A
Q
I
S
N
D
E
E
E
E
F
Site 24
Y550
K
E
Y
K
L
V
P
Y
L
K
D
K
L
K
P
Site 25
Y637
K
E
T
Q
A
P
A
Y
L
I
D
L
M
H
D
Site 26
S689
Q
W
L
E
M
V
E
S
R
Q
M
D
E
S
E
Site 27
S695
E
S
R
Q
M
D
E
S
E
Q
Y
L
Y
G
D
Site 28
Y698
Q
M
D
E
S
E
Q
Y
L
Y
G
D
D
R
I
Site 29
Y700
D
E
S
E
Q
Y
L
Y
G
D
D
R
I
E
P
Site 30
Y708
G
D
D
R
I
E
P
Y
I
H
E
G
D
I
L
Site 31
Y722
L
E
R
P
D
L
F
Y
N
S
D
G
L
I
A
Site 32
S724
R
P
D
L
F
Y
N
S
D
G
L
I
A
S
E
Site 33
S730
N
S
D
G
L
I
A
S
E
G
A
I
S
P
D
Site 34
S735
I
A
S
E
G
A
I
S
P
D
F
F
N
D
Y
Site 35
Y742
S
P
D
F
F
N
D
Y
H
L
Q
N
G
D
V
Site 36
S754
G
D
V
V
G
Q
H
S
F
P
G
S
L
G
M
Site 37
S758
G
Q
H
S
F
P
G
S
L
G
M
D
G
F
G
Site 38
T776
G
I
L
G
R
P
A
T
A
Y
G
F
R
P
D
Site 39
Y778
L
G
R
P
A
T
A
Y
G
F
R
P
D
E
P
Site 40
Y786
G
F
R
P
D
E
P
Y
Y
Y
G
Y
G
S
_
Site 41
Y787
F
R
P
D
E
P
Y
Y
Y
G
Y
G
S
_
_
Site 42
Y788
R
P
D
E
P
Y
Y
Y
G
Y
G
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation