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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAM
Full Name:
Signal transducing adapter molecule 1
Alias:
HSE1; Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; STAM1
Type:
Adapter/scaffold protein
Mass (Da):
59180
Number AA:
540
UniProt ID:
Q92783
International Prot ID:
IPI00020178
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005829
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0005070
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
K
A
T
S
E
M
N
T
A
E
D
W
G
L
I
Site 2
S91
V
C
S
R
D
F
A
S
E
V
S
N
V
L
N
Site 3
S126
F
K
N
D
P
Q
L
S
L
I
S
A
M
I
K
Site 4
T141
N
L
K
E
Q
G
V
T
F
P
A
I
G
S
Q
Site 5
S147
V
T
F
P
A
I
G
S
Q
A
A
E
Q
A
K
Site 6
S156
A
A
E
Q
A
K
A
S
P
A
L
V
A
K
D
Site 7
T166
L
V
A
K
D
P
G
T
V
A
N
K
K
E
E
Site 8
S183
L
A
K
A
I
E
L
S
L
K
E
Q
R
Q
Q
Site 9
S191
L
K
E
Q
R
Q
Q
S
T
T
L
S
T
L
Y
Site 10
T193
E
Q
R
Q
Q
S
T
T
L
S
T
L
Y
P
S
Site 11
S195
R
Q
Q
S
T
T
L
S
T
L
Y
P
S
T
S
Site 12
T196
Q
Q
S
T
T
L
S
T
L
Y
P
S
T
S
S
Site 13
Y198
S
T
T
L
S
T
L
Y
P
S
T
S
S
L
L
Site 14
S200
T
L
S
T
L
Y
P
S
T
S
S
L
L
T
N
Site 15
T201
L
S
T
L
Y
P
S
T
S
S
L
L
T
N
H
Site 16
S202
S
T
L
Y
P
S
T
S
S
L
L
T
N
H
Q
Site 17
S203
T
L
Y
P
S
T
S
S
L
L
T
N
H
Q
H
Site 18
T206
P
S
T
S
S
L
L
T
N
H
Q
H
E
G
R
Site 19
Y219
G
R
K
V
R
A
I
Y
D
F
E
A
A
E
D
Site 20
T230
A
A
E
D
N
E
L
T
F
K
A
G
E
I
I
Site 21
T269
N
F
V
T
A
D
L
T
A
E
P
E
M
I
K
Site 22
T277
A
E
P
E
M
I
K
T
E
K
K
T
V
Q
F
Site 23
T281
M
I
K
T
E
K
K
T
V
Q
F
S
D
D
V
Site 24
S285
E
K
K
T
V
Q
F
S
D
D
V
Q
V
E
T
Site 25
T292
S
D
D
V
Q
V
E
T
I
E
P
E
P
E
P
Site 26
S316
Q
L
L
Q
M
L
Q
S
T
D
P
S
D
D
Q
Site 27
S320
M
L
Q
S
T
D
P
S
D
D
Q
P
D
L
P
Site 28
S355
E
D
I
D
R
K
H
S
E
L
S
E
L
N
V
Site 29
Y371
V
M
E
A
L
S
L
Y
T
K
L
M
N
E
D
Site 30
T372
M
E
A
L
S
L
Y
T
K
L
M
N
E
D
P
Site 31
Y381
L
M
N
E
D
P
M
Y
S
M
Y
A
K
L
Q
Site 32
S382
M
N
E
D
P
M
Y
S
M
Y
A
K
L
Q
N
Site 33
Y384
E
D
P
M
Y
S
M
Y
A
K
L
Q
N
Q
P
Site 34
Y392
A
K
L
Q
N
Q
P
Y
Y
M
Q
S
S
G
V
Site 35
Y393
K
L
Q
N
Q
P
Y
Y
M
Q
S
S
G
V
S
Site 36
S396
N
Q
P
Y
Y
M
Q
S
S
G
V
S
G
S
Q
Site 37
S397
Q
P
Y
Y
M
Q
S
S
G
V
S
G
S
Q
V
Site 38
S400
Y
M
Q
S
S
G
V
S
G
S
Q
V
Y
A
G
Site 39
S402
Q
S
S
G
V
S
G
S
Q
V
Y
A
G
P
P
Site 40
Y405
G
V
S
G
S
Q
V
Y
A
G
P
P
P
S
G
Site 41
Y414
G
P
P
P
S
G
A
Y
L
V
A
G
N
A
Q
Site 42
S423
V
A
G
N
A
Q
M
S
H
L
Q
S
Y
S
L
Site 43
S427
A
Q
M
S
H
L
Q
S
Y
S
L
P
P
E
Q
Site 44
Y428
Q
M
S
H
L
Q
S
Y
S
L
P
P
E
Q
L
Site 45
S429
M
S
H
L
Q
S
Y
S
L
P
P
E
Q
L
S
Site 46
S439
P
E
Q
L
S
S
L
S
Q
A
V
V
P
P
S
Site 47
S446
S
Q
A
V
V
P
P
S
A
N
P
A
L
P
S
Site 48
S453
S
A
N
P
A
L
P
S
Q
Q
T
Q
A
A
Y
Site 49
Y460
S
Q
Q
T
Q
A
A
Y
P
N
T
M
V
S
S
Site 50
T463
T
Q
A
A
Y
P
N
T
M
V
S
S
V
Q
G
Site 51
S467
Y
P
N
T
M
V
S
S
V
Q
G
N
T
Y
P
Site 52
Y473
S
S
V
Q
G
N
T
Y
P
S
Q
A
P
V
Y
Site 53
S475
V
Q
G
N
T
Y
P
S
Q
A
P
V
Y
S
P
Site 54
Y480
Y
P
S
Q
A
P
V
Y
S
P
P
P
A
A
T
Site 55
S481
P
S
Q
A
P
V
Y
S
P
P
P
A
A
T
A
Site 56
Y498
A
T
A
D
V
T
L
Y
Q
N
A
G
P
N
M
Site 57
Y511
N
M
P
Q
V
P
N
Y
N
L
T
S
S
T
L
Site 58
T514
Q
V
P
N
Y
N
L
T
S
S
T
L
P
Q
P
Site 59
S516
P
N
Y
N
L
T
S
S
T
L
P
Q
P
G
G
Site 60
S524
T
L
P
Q
P
G
G
S
Q
Q
P
P
Q
P
Q
Site 61
S535
P
Q
P
Q
Q
P
Y
S
Q
K
A
L
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation