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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RORB
Full Name:
Nuclear receptor ROR-beta
Alias:
Nuclear receptor RZR-beta;Nuclear receptor subfamily 1 group F member 2;Retinoid-related orphan receptor-beta
Type:
Mass (Da):
53220
Number AA:
470
UniProt ID:
Q92753
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
K
S
S
G
I
H
Y
G
V
I
T
C
E
G
Site 2
S54
R
S
Q
Q
N
N
A
S
Y
S
C
P
R
Q
R
Site 3
Y55
S
Q
Q
N
N
A
S
Y
S
C
P
R
Q
R
N
Site 4
S97
A
V
K
F
G
R
M
S
K
K
Q
R
D
S
L
Site 5
S103
M
S
K
K
Q
R
D
S
L
Y
A
E
V
Q
K
Site 6
Y105
K
K
Q
R
D
S
L
Y
A
E
V
Q
K
H
Q
Site 7
Y133
A
E
A
L
A
R
V
Y
S
S
S
I
S
N
G
Site 8
S134
E
A
L
A
R
V
Y
S
S
S
I
S
N
G
L
Site 9
S136
L
A
R
V
Y
S
S
S
I
S
N
G
L
S
N
Site 10
S138
R
V
Y
S
S
S
I
S
N
G
L
S
N
L
N
Site 11
S142
S
S
I
S
N
G
L
S
N
L
N
N
E
T
S
Site 12
S149
S
N
L
N
N
E
T
S
G
T
Y
A
N
G
H
Site 13
T151
L
N
N
E
T
S
G
T
Y
A
N
G
H
V
I
Site 14
S163
H
V
I
D
L
P
K
S
E
G
Y
Y
N
V
D
Site 15
Y166
D
L
P
K
S
E
G
Y
Y
N
V
D
S
G
Q
Site 16
Y167
L
P
K
S
E
G
Y
Y
N
V
D
S
G
Q
P
Site 17
S171
E
G
Y
Y
N
V
D
S
G
Q
P
S
P
D
Q
Site 18
S175
N
V
D
S
G
Q
P
S
P
D
Q
S
G
L
D
Site 19
S179
G
Q
P
S
P
D
Q
S
G
L
D
M
T
G
I
Site 20
Y195
Q
I
K
Q
E
P
I
Y
D
L
T
S
V
P
N
Site 21
T198
Q
E
P
I
Y
D
L
T
S
V
P
N
L
F
T
Site 22
S199
E
P
I
Y
D
L
T
S
V
P
N
L
F
T
Y
Site 23
T205
T
S
V
P
N
L
F
T
Y
S
S
F
N
N
G
Site 24
Y206
S
V
P
N
L
F
T
Y
S
S
F
N
N
G
Q
Site 25
S208
P
N
L
F
T
Y
S
S
F
N
N
G
Q
L
A
Site 26
T237
I
I
K
S
H
L
E
T
C
Q
Y
T
M
E
E
Site 27
Y240
S
H
L
E
T
C
Q
Y
T
M
E
E
L
H
Q
Site 28
Y255
L
A
W
Q
T
H
T
Y
E
E
I
K
A
Y
Q
Site 29
Y261
T
Y
E
E
I
K
A
Y
Q
S
K
S
R
E
A
Site 30
S263
E
E
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Site 31
S265
I
K
A
Y
Q
S
K
S
R
E
A
L
W
Q
Q
Site 32
Y283
Q
I
T
H
A
I
Q
Y
V
V
E
F
A
K
R
Site 33
T328
A
F
N
P
L
N
N
T
V
L
F
E
G
K
Y
Site 34
Y335
T
V
L
F
E
G
K
Y
G
G
M
Q
M
F
K
Site 35
Y400
Q
K
L
Q
E
K
I
Y
F
A
L
Q
H
V
I
Site 36
T416
K
N
H
L
D
D
E
T
L
A
K
L
I
A
K
Site 37
T451
S
H
P
E
I
V
N
T
L
F
P
P
L
Y
K
Site 38
Y457
N
T
L
F
P
P
L
Y
K
E
L
F
N
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation