KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TNR
Full Name:
Tenascin-R
Alias:
Janusin; Restrictin; Restrictin, janusin; Tenascin R; Tenascin-R; TN-R
Type:
Mass (Da):
149548
Number AA:
1358
UniProt ID:
Q92752
International Prot ID:
IPI00160552
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0007411
GO:0007155
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
T
E
R
V
Q
R
Q
S
V
E
E
E
G
G
I
Site 2
Y54
E
E
G
G
I
A
N
Y
N
T
S
S
K
E
Q
Site 3
T56
G
G
I
A
N
Y
N
T
S
S
K
E
Q
P
V
Site 4
S57
G
I
A
N
Y
N
T
S
S
K
E
Q
P
V
V
Site 5
S58
I
A
N
Y
N
T
S
S
K
E
Q
P
V
V
F
Site 6
S81
P
L
D
N
L
C
S
S
G
L
E
A
S
A
E
Site 7
S92
A
S
A
E
Q
E
V
S
A
E
D
E
T
L
A
Site 8
T97
E
V
S
A
E
D
E
T
L
A
E
Y
M
G
Q
Site 9
Y101
E
D
E
T
L
A
E
Y
M
G
Q
T
S
D
H
Site 10
S106
A
E
Y
M
G
Q
T
S
D
H
E
S
Q
V
T
Site 11
S110
G
Q
T
S
D
H
E
S
Q
V
T
F
T
H
R
Site 12
T113
S
D
H
E
S
Q
V
T
F
T
H
R
I
N
F
Site 13
S139
Q
V
L
Q
E
L
L
S
R
I
E
M
L
E
R
Site 14
S149
E
M
L
E
R
E
V
S
V
L
R
D
Q
C
N
Site 15
Y171
A
A
T
G
Q
L
D
Y
I
P
H
C
S
G
H
Site 16
Y203
G
K
N
C
S
E
P
Y
C
P
L
G
C
S
S
Site 17
Y225
Q
C
I
C
D
S
E
Y
S
G
D
D
C
S
E
Site 18
S231
E
Y
S
G
D
D
C
S
E
L
R
C
P
T
D
Site 19
T237
C
S
E
L
R
C
P
T
D
C
S
S
R
G
L
Site 20
S240
L
R
C
P
T
D
C
S
S
R
G
L
C
V
D
Site 21
T257
C
V
C
E
E
P
Y
T
G
E
D
C
R
E
L
Site 22
Y287
T
C
L
C
E
E
G
Y
V
G
E
D
C
G
Q
Site 23
Y318
L
C
V
C
E
E
G
Y
Q
G
P
D
C
S
A
Site 24
S324
G
Y
Q
G
P
D
C
S
A
V
A
P
P
E
D
Site 25
S338
D
L
R
V
A
G
I
S
D
R
S
I
E
L
E
Site 26
Y355
G
P
M
A
V
T
E
Y
V
I
S
Y
Q
P
T
Site 27
S378
Q
R
V
P
G
D
W
S
G
V
T
I
T
E
L
Site 28
T390
T
E
L
E
P
G
L
T
Y
N
I
S
V
Y
A
Site 29
S416
A
K
V
A
T
H
L
S
T
P
Q
G
L
Q
F
Site 30
T417
K
V
A
T
H
L
S
T
P
Q
G
L
Q
F
K
Site 31
S468
Q
V
P
S
D
V
T
S
F
N
Q
T
G
L
K
Site 32
S493
A
L
K
E
Q
A
R
S
P
P
T
S
A
S
V
Site 33
S497
Q
A
R
S
P
P
T
S
A
S
V
S
T
V
I
Site 34
S499
R
S
P
P
T
S
A
S
V
S
T
V
I
D
G
Site 35
S501
P
P
T
S
A
S
V
S
T
V
I
D
G
P
T
Site 36
T502
P
T
S
A
S
V
S
T
V
I
D
G
P
T
Q
Site 37
T548
V
G
G
E
G
G
R
T
T
F
R
L
Q
P
P
Site 38
T549
G
G
E
G
G
R
T
T
F
R
L
Q
P
P
L
Site 39
S557
F
R
L
Q
P
P
L
S
Q
Y
S
V
Q
A
L
Site 40
S560
Q
P
P
L
S
Q
Y
S
V
Q
A
L
R
P
G
Site 41
S568
V
Q
A
L
R
P
G
S
R
Y
E
V
S
V
S
Site 42
Y570
A
L
R
P
G
S
R
Y
E
V
S
V
S
A
V
Site 43
S573
P
G
S
R
Y
E
V
S
V
S
A
V
R
G
T
Site 44
S575
S
R
Y
E
V
S
V
S
A
V
R
G
T
N
E
Site 45
T580
S
V
S
A
V
R
G
T
N
E
S
D
S
A
T
Site 46
S583
A
V
R
G
T
N
E
S
D
S
A
T
T
Q
F
Site 47
T587
T
N
E
S
D
S
A
T
T
Q
F
T
T
E
I
Site 48
S604
P
K
N
L
R
V
G
S
R
T
A
T
S
L
D
Site 49
T606
N
L
R
V
G
S
R
T
A
T
S
L
D
L
E
Site 50
T608
R
V
G
S
R
T
A
T
S
L
D
L
E
W
D
Site 51
S617
L
D
L
E
W
D
N
S
E
A
E
V
Q
E
Y
Site 52
Y624
S
E
A
E
V
Q
E
Y
K
V
V
Y
S
T
L
Site 53
Y636
S
T
L
A
G
E
Q
Y
H
E
V
L
V
P
R
Site 54
T648
V
P
R
G
I
G
P
T
T
R
A
T
L
T
D
Site 55
S667
T
E
Y
G
V
G
I
S
A
V
M
N
S
Q
Q
Site 56
S672
G
I
S
A
V
M
N
S
Q
Q
S
V
P
A
T
Site 57
T679
S
Q
Q
S
V
P
A
T
M
N
A
R
T
E
L
Site 58
T684
P
A
T
M
N
A
R
T
E
L
D
S
P
R
D
Site 59
S688
N
A
R
T
E
L
D
S
P
R
D
L
M
V
T
Site 60
T695
S
P
R
D
L
M
V
T
A
S
S
E
T
S
I
Site 61
S703
A
S
S
E
T
S
I
S
L
I
W
T
K
A
S
Site 62
Y716
A
S
G
P
I
D
H
Y
R
I
T
F
T
P
S
Site 63
T719
P
I
D
H
Y
R
I
T
F
T
P
S
S
G
I
Site 64
T721
D
H
Y
R
I
T
F
T
P
S
S
G
I
A
S
Site 65
S723
Y
R
I
T
F
T
P
S
S
G
I
A
S
E
V
Site 66
S724
R
I
T
F
T
P
S
S
G
I
A
S
E
V
T
Site 67
S728
T
P
S
S
G
I
A
S
E
V
T
V
P
K
D
Site 68
T731
S
G
I
A
S
E
V
T
V
P
K
D
R
T
S
Site 69
S738
T
V
P
K
D
R
T
S
Y
T
L
T
D
L
E
Site 70
Y739
V
P
K
D
R
T
S
Y
T
L
T
D
L
E
P
Site 71
T740
P
K
D
R
T
S
Y
T
L
T
D
L
E
P
G
Site 72
T742
D
R
T
S
Y
T
L
T
D
L
E
P
G
A
E
Site 73
S753
P
G
A
E
Y
I
I
S
V
T
A
E
R
G
R
Site 74
S763
A
E
R
G
R
Q
Q
S
L
E
S
T
V
D
A
Site 75
S766
G
R
Q
Q
S
L
E
S
T
V
D
A
F
T
G
Site 76
T767
R
Q
Q
S
L
E
S
T
V
D
A
F
T
G
F
Site 77
T772
E
S
T
V
D
A
F
T
G
F
R
P
I
S
H
Site 78
S783
P
I
S
H
L
H
F
S
H
V
T
S
S
S
V
Site 79
S788
H
F
S
H
V
T
S
S
S
V
N
I
T
W
S
Site 80
S789
F
S
H
V
T
S
S
S
V
N
I
T
W
S
D
Site 81
T793
T
S
S
S
V
N
I
T
W
S
D
P
S
P
P
Site 82
S795
S
S
V
N
I
T
W
S
D
P
S
P
P
A
D
Site 83
S798
N
I
T
W
S
D
P
S
P
P
A
D
R
L
I
Site 84
Y808
A
D
R
L
I
L
N
Y
S
P
R
D
E
E
E
Site 85
S809
D
R
L
I
L
N
Y
S
P
R
D
E
E
E
E
Site 86
S821
E
E
E
M
M
E
V
S
L
D
A
T
K
R
H
Site 87
T871
I
D
P
P
K
D
I
T
I
S
N
V
T
K
D
Site 88
S873
P
P
K
D
I
T
I
S
N
V
T
K
D
S
V
Site 89
S879
I
S
N
V
T
K
D
S
V
M
V
S
W
S
P
Site 90
S883
T
K
D
S
V
M
V
S
W
S
P
P
V
A
S
Site 91
S890
S
W
S
P
P
V
A
S
F
D
Y
Y
R
V
S
Site 92
Y893
P
P
V
A
S
F
D
Y
Y
R
V
S
Y
R
P
Site 93
Y894
P
V
A
S
F
D
Y
Y
R
V
S
Y
R
P
T
Site 94
S897
S
F
D
Y
Y
R
V
S
Y
R
P
T
Q
V
G
Site 95
Y898
F
D
Y
Y
R
V
S
Y
R
P
T
Q
V
G
R
Site 96
T901
Y
R
V
S
Y
R
P
T
Q
V
G
R
L
D
S
Site 97
S908
T
Q
V
G
R
L
D
S
S
V
V
P
N
T
V
Site 98
S909
Q
V
G
R
L
D
S
S
V
V
P
N
T
V
T
Site 99
T927
I
T
R
L
N
P
A
T
E
Y
E
I
S
L
N
Site 100
Y929
R
L
N
P
A
T
E
Y
E
I
S
L
N
S
V
Site 101
S932
P
A
T
E
Y
E
I
S
L
N
S
V
R
G
R
Site 102
S935
E
Y
E
I
S
L
N
S
V
R
G
R
E
E
S
Site 103
S942
S
V
R
G
R
E
E
S
E
R
I
C
T
L
V
Site 104
T947
E
E
S
E
R
I
C
T
L
V
H
T
A
M
D
Site 105
T951
R
I
C
T
L
V
H
T
A
M
D
N
P
V
D
Site 106
T1018
L
L
P
S
T
H
Y
T
A
T
M
Y
A
T
N
Site 107
Y1022
T
H
Y
T
A
T
M
Y
A
T
N
G
P
L
T
Site 108
S1030
A
T
N
G
P
L
T
S
G
T
I
S
T
N
F
Site 109
T1032
N
G
P
L
T
S
G
T
I
S
T
N
F
S
T
Site 110
T1048
L
D
P
P
A
N
L
T
A
S
E
V
T
R
Q
Site 111
S1050
P
P
A
N
L
T
A
S
E
V
T
R
Q
S
A
Site 112
S1056
A
S
E
V
T
R
Q
S
A
L
I
S
W
Q
P
Site 113
S1060
T
R
Q
S
A
L
I
S
W
Q
P
P
R
A
E
Site 114
Y1071
P
R
A
E
I
E
N
Y
V
L
T
Y
K
S
T
Site 115
T1074
E
I
E
N
Y
V
L
T
Y
K
S
T
D
G
S
Site 116
Y1075
I
E
N
Y
V
L
T
Y
K
S
T
D
G
S
R
Site 117
S1077
N
Y
V
L
T
Y
K
S
T
D
G
S
R
K
E
Site 118
S1081
T
Y
K
S
T
D
G
S
R
K
E
L
I
V
D
Site 119
T1115
L
L
Q
A
A
Q
D
T
T
W
S
S
I
T
S
Site 120
T1116
L
Q
A
A
Q
D
T
T
W
S
S
I
T
S
T
Site 121
S1118
A
A
Q
D
T
T
W
S
S
I
T
S
T
A
F
Site 122
S1119
A
Q
D
T
T
W
S
S
I
T
S
T
A
F
T
Site 123
S1122
T
T
W
S
S
I
T
S
T
A
F
T
T
G
G
Site 124
T1123
T
W
S
S
I
T
S
T
A
F
T
T
G
G
R
Site 125
T1147
Q
H
L
M
N
G
D
T
L
S
G
V
Y
P
I
Site 126
Y1167
L
S
Q
K
L
Q
V
Y
C
D
M
T
T
D
G
Site 127
Y1197
F
F
R
K
W
A
D
Y
R
V
G
F
G
N
V
Site 128
T1219
L
D
N
I
H
R
I
T
S
Q
G
R
Y
E
L
Site 129
S1220
D
N
I
H
R
I
T
S
Q
G
R
Y
E
L
R
Site 130
Y1224
R
I
T
S
Q
G
R
Y
E
L
R
V
D
M
R
Site 131
S1240
G
Q
E
A
A
F
A
S
Y
D
R
F
S
V
E
Site 132
Y1241
Q
E
A
A
F
A
S
Y
D
R
F
S
V
E
D
Site 133
S1245
F
A
S
Y
D
R
F
S
V
E
D
S
R
N
L
Site 134
S1249
D
R
F
S
V
E
D
S
R
N
L
Y
K
L
R
Site 135
Y1253
V
E
D
S
R
N
L
Y
K
L
R
I
G
S
Y
Site 136
S1259
L
Y
K
L
R
I
G
S
Y
N
G
T
A
G
D
Site 137
Y1260
Y
K
L
R
I
G
S
Y
N
G
T
A
G
D
S
Site 138
T1263
R
I
G
S
Y
N
G
T
A
G
D
S
L
S
Y
Site 139
S1267
Y
N
G
T
A
G
D
S
L
S
Y
H
Q
G
R
Site 140
S1269
G
T
A
G
D
S
L
S
Y
H
Q
G
R
P
F
Site 141
S1277
Y
H
Q
G
R
P
F
S
T
E
D
R
D
N
D
Site 142
Y1294
V
T
N
C
A
M
S
Y
K
G
A
W
W
Y
K
Site 143
Y1312
R
T
N
L
N
G
K
Y
G
E
S
R
H
S
Q
Site 144
Y1343
V
E
M
K
M
R
P
Y
N
H
R
L
M
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation