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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF4B
Full Name:
Transcription initiation factor TFIID subunit 4B
Alias:
Taf2c2; taf4b; taf4b rna polymerase ii, tata box binding protein (tbp)-associated factor, 105kda; tafii105; tata box binding protein (tbp)-associated factor 4b; tbp associated factor; transcription initiation factor TFIID 105 kDa subunit
Type:
Mass (Da):
91091
Number AA:
862
UniProt ID:
Q92750
International Prot ID:
IPI00023258
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005669
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0051059
GO:0003700
GO:0016986
PhosphoSite+
KinaseNET
Biological Process:
GO:0006368
GO:0006355
GO:0006367
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S59
V
C
V
E
P
T
A
S
Q
P
L
R
S
P
V
Site 2
S83
V
S
A
P
P
K
V
S
S
G
P
R
L
P
A
Site 3
S84
S
A
P
P
K
V
S
S
G
P
R
L
P
A
P
Site 4
T116
N
L
Q
L
P
P
G
T
V
L
I
K
S
N
S
Site 5
S130
S
G
P
L
M
L
V
S
P
Q
Q
T
V
T
R
Site 6
T134
M
L
V
S
P
Q
Q
T
V
T
R
A
E
T
T
Site 7
T140
Q
T
V
T
R
A
E
T
T
S
N
I
T
S
R
Site 8
S142
V
T
R
A
E
T
T
S
N
I
T
S
R
P
A
Site 9
S146
E
T
T
S
N
I
T
S
R
P
A
V
P
A
N
Site 10
T161
P
Q
T
V
K
I
C
T
V
P
N
S
S
S
Q
Site 11
S165
K
I
C
T
V
P
N
S
S
S
Q
L
I
K
K
Site 12
T190
Q
I
G
T
T
V
V
T
T
V
P
K
P
S
S
Site 13
S197
T
T
V
P
K
P
S
S
V
Q
S
V
A
V
P
Site 14
S200
P
K
P
S
S
V
Q
S
V
A
V
P
T
S
V
Site 15
T211
P
T
S
V
V
T
V
T
P
G
K
P
L
N
T
Site 16
T218
T
P
G
K
P
L
N
T
V
T
T
L
K
P
S
Site 17
T220
G
K
P
L
N
T
V
T
T
L
K
P
S
S
L
Site 18
T221
K
P
L
N
T
V
T
T
L
K
P
S
S
L
G
Site 19
S226
V
T
T
L
K
P
S
S
L
G
A
S
S
T
P
Site 20
S230
K
P
S
S
L
G
A
S
S
T
P
S
N
E
P
Site 21
S231
P
S
S
L
G
A
S
S
T
P
S
N
E
P
N
Site 22
T232
S
S
L
G
A
S
S
T
P
S
N
E
P
N
L
Site 23
S234
L
G
A
S
S
T
P
S
N
E
P
N
L
K
A
Site 24
S244
P
N
L
K
A
E
N
S
A
A
V
Q
I
N
L
Site 25
S277
I
K
L
A
C
S
G
S
Q
S
P
E
M
G
Q
Site 26
S279
L
A
C
S
G
S
Q
S
P
E
M
G
Q
N
V
Site 27
Y308
E
E
F
T
R
K
L
Y
V
E
L
K
S
S
P
Site 28
S313
K
L
Y
V
E
L
K
S
S
P
Q
P
H
L
V
Site 29
S314
L
Y
V
E
L
K
S
S
P
Q
P
H
L
V
P
Site 30
S337
L
R
Q
L
L
P
N
S
Q
S
F
I
Q
Q
C
Site 31
S339
Q
L
L
P
N
S
Q
S
F
I
Q
Q
C
V
Q
Site 32
T369
T
T
S
P
V
V
T
T
T
V
S
S
S
Q
S
Site 33
T370
T
S
P
V
V
T
T
T
V
S
S
S
Q
S
E
Site 34
S372
P
V
V
T
T
T
V
S
S
S
Q
S
E
K
S
Site 35
S374
V
T
T
T
V
S
S
S
Q
S
E
K
S
I
I
Site 36
S376
T
T
V
S
S
S
Q
S
E
K
S
I
I
V
S
Site 37
S379
S
S
S
Q
S
E
K
S
I
I
V
S
G
A
T
Site 38
S383
S
E
K
S
I
I
V
S
G
A
T
A
P
R
T
Site 39
T390
S
G
A
T
A
P
R
T
V
S
V
Q
T
L
N
Site 40
T395
P
R
T
V
S
V
Q
T
L
N
P
L
A
G
P
Site 41
S489
P
S
V
K
P
V
V
S
S
A
G
T
T
S
D
Site 42
S495
V
S
S
A
G
T
T
S
D
K
P
V
I
G
T
Site 43
S516
A
Q
P
G
P
V
L
S
Q
P
A
G
I
P
Q
Site 44
T544
G
G
N
E
K
Q
V
T
T
I
S
H
S
S
T
Site 45
T545
G
N
E
K
Q
V
T
T
I
S
H
S
S
T
L
Site 46
S547
E
K
Q
V
T
T
I
S
H
S
S
T
L
T
I
Site 47
T551
T
T
I
S
H
S
S
T
L
T
I
Q
K
C
G
Site 48
T553
I
S
H
S
S
T
L
T
I
Q
K
C
G
Q
K
Site 49
T566
Q
K
T
M
P
V
N
T
I
I
P
T
S
Q
F
Site 50
T570
P
V
N
T
I
I
P
T
S
Q
F
P
P
A
S
Site 51
S591
L
P
G
N
K
I
L
S
L
Q
A
S
P
T
Q
Site 52
S595
K
I
L
S
L
Q
A
S
P
T
Q
K
N
R
I
Site 53
S608
R
I
K
E
N
V
T
S
C
F
R
D
E
D
D
Site 54
T620
E
D
D
I
N
D
V
T
S
M
A
G
V
N
L
Site 55
S621
D
D
I
N
D
V
T
S
M
A
G
V
N
L
N
Site 56
T644
T
N
S
E
L
V
G
T
L
I
Q
S
C
K
D
Site 57
T674
I
G
K
K
H
D
I
T
E
L
N
S
D
A
V
Site 58
S678
H
D
I
T
E
L
N
S
D
A
V
N
L
I
S
Site 59
S685
S
D
A
V
N
L
I
S
Q
A
T
Q
E
R
L
Site 60
T700
R
G
L
L
E
K
L
T
A
I
A
Q
H
R
M
Site 61
T708
A
I
A
Q
H
R
M
T
T
Y
K
A
S
E
N
Site 62
T709
I
A
Q
H
R
M
T
T
Y
K
A
S
E
N
Y
Site 63
S720
S
E
N
Y
I
L
C
S
D
T
R
S
Q
L
K
Site 64
T722
N
Y
I
L
C
S
D
T
R
S
Q
L
K
F
L
Site 65
S724
I
L
C
S
D
T
R
S
Q
L
K
F
L
E
K
Site 66
S754
M
L
L
K
A
A
K
S
R
S
N
K
E
D
P
Site 67
S756
L
K
A
A
K
S
R
S
N
K
E
D
P
E
Q
Site 68
T789
Q
H
R
D
A
N
L
T
A
L
A
A
I
G
P
Site 69
T822
A
S
G
T
S
S
L
T
A
T
K
Q
L
H
R
Site 70
T824
G
T
S
S
L
T
A
T
K
Q
L
H
R
P
R
Site 71
T833
Q
L
H
R
P
R
I
T
R
I
C
L
R
D
L
Site 72
Y852
E
Q
E
R
E
M
K
Y
S
R
A
L
Y
L
A
Site 73
S853
Q
E
R
E
M
K
Y
S
R
A
L
Y
L
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation