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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARPC1A
Full Name:
Actin-related protein 2/3 complex subunit 1A
Alias:
Actin-related protein 2/3 complex 1A; ARC1A; SOP2L; SOP2-like protein
Type:
Cytoskeleton protein, Component of the Arp2/3 complex which is involved in regulation of actin polymerization
Mass (Da):
41569
Number AA:
370
UniProt ID:
Q92747
International Prot ID:
IPI00333068
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0030833
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
H
A
W
N
R
D
R
T
Q
I
A
L
S
P
N
Site 2
S26
D
R
T
Q
I
A
L
S
P
N
N
H
E
V
H
Site 3
T69
P
K
S
D
R
I
V
T
C
G
A
D
R
N
A
Site 4
Y77
C
G
A
D
R
N
A
Y
V
W
S
Q
K
D
G
Site 5
S105
A
A
T
F
V
K
W
S
P
L
E
N
K
F
A
Site 6
Y124
A
R
L
I
S
V
C
Y
F
E
S
E
N
D
W
Site 7
S143
H
I
K
K
P
I
R
S
T
V
L
S
L
D
W
Site 8
T144
I
K
K
P
I
R
S
T
V
L
S
L
D
W
H
Site 9
S147
P
I
R
S
T
V
L
S
L
D
W
H
P
N
N
Site 10
Y172
K
C
R
V
F
S
A
Y
I
K
E
V
D
E
K
Site 11
S182
E
V
D
E
K
P
A
S
T
P
W
G
S
K
M
Site 12
T183
V
D
E
K
P
A
S
T
P
W
G
S
K
M
P
Site 13
S187
P
A
S
T
P
W
G
S
K
M
P
F
G
Q
L
Site 14
S196
M
P
F
G
Q
L
M
S
E
F
G
G
S
G
T
Site 15
S201
L
M
S
E
F
G
G
S
G
T
G
G
W
V
H
Site 16
S211
G
G
W
V
H
G
V
S
F
S
A
S
G
S
R
Site 17
S223
G
S
R
L
A
W
V
S
H
D
S
T
V
S
V
Site 18
T227
A
W
V
S
H
D
S
T
V
S
V
A
D
A
S
Site 19
S229
V
S
H
D
S
T
V
S
V
A
D
A
S
K
S
Site 20
S236
S
V
A
D
A
S
K
S
V
Q
V
S
T
L
K
Site 21
S240
A
S
K
S
V
Q
V
S
T
L
K
T
E
F
L
Site 22
T281
Y
D
D
R
G
C
L
T
F
V
S
K
L
D
I
Site 23
S284
R
G
C
L
T
F
V
S
K
L
D
I
P
K
Q
Site 24
S298
Q
S
I
Q
R
N
M
S
A
M
E
R
F
R
N
Site 25
T311
R
N
M
D
K
R
A
T
T
E
D
R
N
T
A
Site 26
T312
N
M
D
K
R
A
T
T
E
D
R
N
T
A
L
Site 27
T317
A
T
T
E
D
R
N
T
A
L
E
T
L
H
Q
Site 28
Y333
S
I
T
Q
V
S
I
Y
E
V
D
K
Q
D
C
Site 29
T359
M
T
I
W
D
F
K
T
L
E
S
S
I
Q
G
Site 30
S363
D
F
K
T
L
E
S
S
I
Q
G
L
R
I
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation