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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAD54L
Full Name:
DNA repair and recombination protein RAD54-like
Alias:
HHR54; HR54; RAD54; RAD54 homolog; RAD54A; RAD54-like
Type:
Cell cycle regulation, DNA repair, Helicase, Carbohydrate Metabolism group, Starch and sucrose metabolism family, Metabolism of Cofactors and Vitamins group, Folate biosynthesis family
Mass (Da):
84352
Number AA:
747
UniProt ID:
Q92698
International Prot ID:
IPI00294292
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003677
GO:0004386
PhosphoSite+
KinaseNET
Biological Process:
GO:0007126
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
R
R
S
L
A
P
S
Q
L
A
Site 2
S8
M
R
R
S
L
A
P
S
Q
L
A
K
R
K
P
Site 3
S19
K
R
K
P
E
G
R
S
C
D
D
E
D
W
Q
Site 4
T31
D
W
Q
P
G
L
V
T
P
R
K
R
K
S
S
Site 5
S37
V
T
P
R
K
R
K
S
S
S
E
T
Q
I
Q
Site 6
S38
T
P
R
K
R
K
S
S
S
E
T
Q
I
Q
E
Site 7
S39
P
R
K
R
K
S
S
S
E
T
Q
I
Q
E
C
Site 8
T41
K
R
K
S
S
S
E
T
Q
I
Q
E
C
F
L
Site 9
S49
Q
I
Q
E
C
F
L
S
P
F
R
K
P
L
S
Site 10
S56
S
P
F
R
K
P
L
S
Q
L
T
N
Q
P
P
Site 11
T59
R
K
P
L
S
Q
L
T
N
Q
P
P
C
L
D
Site 12
S68
Q
P
P
C
L
D
S
S
Q
H
E
A
F
I
R
Site 13
S76
Q
H
E
A
F
I
R
S
I
L
S
K
P
F
K
Site 14
Y89
F
K
V
P
I
P
N
Y
Q
G
P
L
G
S
R
Site 15
Y121
E
K
D
A
L
V
L
Y
E
P
P
P
L
S
A
Site 16
S127
L
Y
E
P
P
P
L
S
A
H
D
Q
L
K
L
Site 17
T169
K
F
L
W
E
C
V
T
S
R
R
I
P
G
S
Site 18
S176
T
S
R
R
I
P
G
S
H
G
C
I
M
A
D
Site 19
T199
Q
C
I
T
L
M
W
T
L
L
R
Q
S
P
E
Site 20
S204
M
W
T
L
L
R
Q
S
P
E
C
K
P
E
I
Site 21
Y227
S
S
L
V
K
N
W
Y
N
E
V
G
K
W
L
Site 22
S267
N
Q
R
G
A
R
V
S
S
P
I
L
I
I
S
Site 23
S304
E
G
H
R
L
K
N
S
E
N
Q
T
Y
Q
A
Site 24
T308
L
K
N
S
E
N
Q
T
Y
Q
A
L
D
S
L
Site 25
Y309
K
N
S
E
N
Q
T
Y
Q
A
L
D
S
L
N
Site 26
S314
Q
T
Y
Q
A
L
D
S
L
N
T
S
R
R
V
Site 27
T317
Q
A
L
D
S
L
N
T
S
R
R
V
L
I
S
Site 28
S318
A
L
D
S
L
N
T
S
R
R
V
L
I
S
G
Site 29
S324
T
S
R
R
V
L
I
S
G
T
P
I
Q
N
D
Site 30
S370
K
G
R
D
A
A
A
S
E
A
D
R
Q
L
G
Site 31
T385
E
E
R
L
R
E
L
T
S
I
V
N
R
C
L
Site 32
T396
N
R
C
L
I
R
R
T
S
D
I
L
S
K
Y
Site 33
S397
R
C
L
I
R
R
T
S
D
I
L
S
K
Y
L
Site 34
S401
R
R
T
S
D
I
L
S
K
Y
L
P
V
K
I
Site 35
Y403
T
S
D
I
L
S
K
Y
L
P
V
K
I
E
Q
Site 36
Y424
T
P
L
Q
T
E
L
Y
K
R
F
L
R
Q
A
Site 37
S445
L
E
G
K
M
S
V
S
S
L
S
S
I
T
S
Site 38
S446
E
G
K
M
S
V
S
S
L
S
S
I
T
S
L
Site 39
S448
K
M
S
V
S
S
L
S
S
I
T
S
L
K
K
Site 40
S452
S
S
L
S
S
I
T
S
L
K
K
L
C
N
H
Site 41
Y485
L
D
L
F
P
P
G
Y
S
S
K
A
L
E
P
Site 42
Y503
G
K
M
L
V
L
D
Y
I
L
A
V
T
R
S
Site 43
T508
L
D
Y
I
L
A
V
T
R
S
R
S
S
D
K
Site 44
S510
Y
I
L
A
V
T
R
S
R
S
S
D
K
V
V
Site 45
S513
A
V
T
R
S
R
S
S
D
K
V
V
L
V
S
Site 46
Y538
K
L
C
R
A
R
R
Y
L
Y
V
R
L
D
G
Site 47
Y540
C
R
A
R
R
Y
L
Y
V
R
L
D
G
T
M
Site 48
T546
L
Y
V
R
L
D
G
T
M
S
I
K
K
R
A
Site 49
S548
V
R
L
D
G
T
M
S
I
K
K
R
A
K
V
Site 50
S561
K
V
V
E
R
F
N
S
P
S
S
P
D
F
V
Site 51
S563
V
E
R
F
N
S
P
S
S
P
D
F
V
F
M
Site 52
S564
E
R
F
N
S
P
S
S
P
D
F
V
F
M
L
Site 53
Y617
D
G
Q
K
K
T
C
Y
I
Y
R
L
L
S
A
Site 54
S623
C
Y
I
Y
R
L
L
S
A
G
T
I
E
E
K
Site 55
S636
E
K
I
F
Q
R
Q
S
H
K
K
A
L
S
S
Site 56
S657
Q
D
V
E
R
H
F
S
L
G
E
L
K
E
L
Site 57
S671
L
F
I
L
D
E
A
S
L
S
D
T
H
D
R
Site 58
S673
I
L
D
E
A
S
L
S
D
T
H
D
R
L
H
Site 59
T675
D
E
A
S
L
S
D
T
H
D
R
L
H
C
R
Site 60
S697
I
R
P
P
P
D
G
S
D
C
T
S
D
L
A
Site 61
T700
P
P
D
G
S
D
C
T
S
D
L
A
G
W
N
Site 62
S701
P
D
G
S
D
C
T
S
D
L
A
G
W
N
H
Site 63
T732
D
A
A
S
T
A
I
T
F
V
F
H
Q
R
S
Site 64
S739
T
F
V
F
H
Q
R
S
H
E
E
Q
R
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation