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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIGK
Full Name:
GPI-anchor transamidase
Alias:
GPI8 homolog;Phosphatidylinositol-glycan biosynthesis class K protein
Type:
Mass (Da):
Number AA:
UniProt ID:
Q92643
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042765
Uniprot
OncoNet
Molecular Function:
GO:0003923
GO:0004197
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016255
GO:0006467
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
S
F
G
S
V
A
A
S
H
I
E
D
Q
A
E
Site 2
Y59
T
S
R
F
W
F
N
Y
R
H
V
A
N
T
L
Site 3
T65
N
Y
R
H
V
A
N
T
L
S
V
Y
R
S
V
Site 4
S67
R
H
V
A
N
T
L
S
V
Y
R
S
V
K
R
Site 5
Y69
V
A
N
T
L
S
V
Y
R
S
V
K
R
L
G
Site 6
S71
N
T
L
S
V
Y
R
S
V
K
R
L
G
I
P
Site 7
T101
P
R
N
P
K
P
A
T
V
F
S
H
K
N
M
Site 8
Y113
K
N
M
E
L
N
V
Y
G
D
D
V
E
V
D
Site 9
Y121
G
D
D
V
E
V
D
Y
R
S
Y
E
V
T
V
Site 10
S123
D
V
E
V
D
Y
R
S
Y
E
V
T
V
E
N
Site 11
Y124
V
E
V
D
Y
R
S
Y
E
V
T
V
E
N
F
Site 12
T127
D
Y
R
S
Y
E
V
T
V
E
N
F
L
R
V
Site 13
T136
E
N
F
L
R
V
L
T
G
R
I
P
P
S
T
Site 14
S142
L
T
G
R
I
P
P
S
T
P
R
S
K
R
L
Site 15
T143
T
G
R
I
P
P
S
T
P
R
S
K
R
L
L
Site 16
S146
I
P
P
S
T
P
R
S
K
R
L
L
S
D
D
Site 17
S151
P
R
S
K
R
L
L
S
D
D
R
S
N
I
L
Site 18
S155
R
L
L
S
D
D
R
S
N
I
L
I
Y
M
T
Site 19
Y160
D
R
S
N
I
L
I
Y
M
T
G
H
G
G
N
Site 20
S175
G
F
L
K
F
Q
D
S
E
E
I
T
N
I
E
Site 21
Y196
Q
M
W
Q
K
R
R
Y
N
E
L
L
F
I
I
Site 22
T205
E
L
L
F
I
I
D
T
C
Q
G
A
S
M
Y
Site 23
Y212
T
C
Q
G
A
S
M
Y
E
R
F
Y
S
P
N
Site 24
Y216
A
S
M
Y
E
R
F
Y
S
P
N
I
M
A
L
Site 25
S217
S
M
Y
E
R
F
Y
S
P
N
I
M
A
L
A
Site 26
S232
S
S
Q
V
G
E
D
S
L
S
H
Q
P
D
P
Site 27
S234
Q
V
G
E
D
S
L
S
H
Q
P
D
P
A
I
Site 28
S264
L
E
E
I
N
P
A
S
Q
T
N
M
N
D
L
Site 29
S282
C
P
K
S
L
C
V
S
T
P
G
H
R
T
D
Site 30
T283
P
K
S
L
C
V
S
T
P
G
H
R
T
D
L
Site 31
T313
S
V
R
K
V
E
I
T
T
E
T
I
K
L
Q
Site 32
S323
T
I
K
L
Q
Q
D
S
E
I
M
E
S
S
Y
Site 33
S328
Q
D
S
E
I
M
E
S
S
Y
K
E
D
Q
M
Site 34
S329
D
S
E
I
M
E
S
S
Y
K
E
D
Q
M
D
Site 35
Y345
K
L
M
E
P
L
K
Y
A
E
Q
L
P
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation