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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NPIPL3
Full Name:
Nuclear pore complex-interacting protein-like 3
Alias:
Protein pps22-1
Type:
Mass (Da):
116847
Number AA:
1050
UniProt ID:
Q92617
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
S
H
D
Q
G
Q
L
T
K
E
L
Q
Q
H
V
Site 2
Y37
S
V
T
C
P
C
E
Y
L
R
K
V
I
N
T
Site 3
T44
Y
L
R
K
V
I
N
T
L
A
D
H
H
H
R
Site 4
T53
A
D
H
H
H
R
G
T
D
F
G
G
S
P
W
Site 5
S100
S
R
N
G
H
D
G
S
T
D
V
Q
Q
R
A
Site 6
T101
R
N
G
H
D
G
S
T
D
V
Q
Q
R
A
W
Site 7
S110
V
Q
Q
R
A
W
R
S
N
R
R
R
Q
E
G
Site 8
S120
R
R
Q
E
G
L
R
S
I
C
M
H
T
K
K
Site 9
T125
L
R
S
I
C
M
H
T
K
K
R
V
S
S
F
Site 10
S130
M
H
T
K
K
R
V
S
S
F
R
G
N
K
I
Site 11
S131
H
T
K
K
R
V
S
S
F
R
G
N
K
I
G
Site 12
T144
I
G
L
K
D
V
I
T
L
R
R
H
V
E
T
Site 13
T151
T
L
R
R
H
V
E
T
K
V
R
A
K
I
R
Site 14
T163
K
I
R
K
R
K
V
T
T
K
I
N
H
H
D
Site 15
T178
K
I
N
G
K
R
K
T
A
R
K
Q
K
M
F
Site 16
Y198
L
R
R
R
A
E
D
Y
H
K
C
K
I
P
P
Site 17
S206
H
K
C
K
I
P
P
S
A
R
K
A
L
C
N
Site 18
S225
A
A
A
E
H
R
H
S
S
G
L
P
Y
W
P
Site 19
S226
A
A
E
H
R
H
S
S
G
L
P
Y
W
P
Y
Site 20
Y230
R
H
S
S
G
L
P
Y
W
P
Y
L
T
A
E
Site 21
Y233
S
G
L
P
Y
W
P
Y
L
T
A
E
T
L
K
Site 22
T251
G
H
Q
P
P
P
P
T
Q
Q
H
S
I
T
D
Site 23
S255
P
P
P
T
Q
Q
H
S
I
T
D
N
S
L
S
Site 24
T257
P
T
Q
Q
H
S
I
T
D
N
S
L
S
L
K
Site 25
S260
Q
H
S
I
T
D
N
S
L
S
L
K
T
P
P
Site 26
S262
S
I
T
D
N
S
L
S
L
K
T
P
P
E
C
Site 27
T265
D
N
S
L
S
L
K
T
P
P
E
C
L
L
T
Site 28
T272
T
P
P
E
C
L
L
T
P
L
P
P
S
A
D
Site 29
S277
L
L
T
P
L
P
P
S
A
D
D
N
L
K
T
Site 30
T284
S
A
D
D
N
L
K
T
P
P
E
C
V
L
T
Site 31
T291
T
P
P
E
C
V
L
T
P
L
P
P
S
A
D
Site 32
S296
V
L
T
P
L
P
P
S
A
D
D
N
L
K
T
Site 33
T322
S
A
D
D
N
L
K
T
P
P
E
C
L
L
T
Site 34
S357
L
P
P
S
A
L
P
S
A
P
P
S
A
D
D
Site 35
S361
A
L
P
S
A
P
P
S
A
D
D
N
L
K
T
Site 36
T368
S
A
D
D
N
L
K
T
R
A
E
C
L
L
H
Site 37
S380
L
L
H
P
L
P
P
S
A
D
D
N
L
K
T
Site 38
T387
S
A
D
D
N
L
K
T
P
S
E
R
Q
L
T
Site 39
S389
D
D
N
L
K
T
P
S
E
R
Q
L
T
P
L
Site 40
T394
T
P
S
E
R
Q
L
T
P
L
P
P
S
A
P
Site 41
S399
Q
L
T
P
L
P
P
S
A
P
P
S
A
D
D
Site 42
S403
L
P
P
S
A
P
P
S
A
D
D
N
I
K
T
Site 43
T410
S
A
D
D
N
I
K
T
P
A
E
R
L
R
G
Site 44
S422
L
R
G
P
L
P
P
S
A
D
D
N
L
K
T
Site 45
S515
D
D
N
L
K
T
P
S
E
R
Q
L
T
A
L
Site 46
T520
T
P
S
E
R
Q
L
T
A
L
P
P
S
A
D
Site 47
S525
Q
L
T
A
L
P
P
S
A
D
D
N
I
K
T
Site 48
T574
S
A
D
D
N
I
K
T
P
A
F
H
P
Q
R
Site 49
S592
S
R
H
L
P
S
V
S
S
L
P
F
H
P
Q
Site 50
S593
R
H
L
P
S
V
S
S
L
P
F
H
P
Q
L
Site 51
S781
I
I
S
R
H
L
P
S
V
C
G
E
R
L
R
Site 52
T927
S
A
D
D
N
L
K
T
P
P
L
A
T
Q
E
Site 53
S983
A
A
D
V
E
P
S
S
P
E
P
K
R
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation