KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PHF16
Full Name:
Protein Jade-3
Alias:
JADE3; KIAA0215; PHD finger protein 16
Type:
Transcription protein
Mass (Da):
93808
Number AA:
823
UniProt ID:
Q92613
International Prot ID:
IPI00006077
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000123
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0043966
GO:0043983
GO:0043981
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
K
R
H
R
P
V
S
S
S
D
S
S
D
E
Site 2
S9
K
R
H
R
P
V
S
S
S
D
S
S
D
E
S
Site 3
S10
R
H
R
P
V
S
S
S
D
S
S
D
E
S
P
Site 4
S12
R
P
V
S
S
S
D
S
S
D
E
S
P
S
T
Site 5
S13
P
V
S
S
S
D
S
S
D
E
S
P
S
T
S
Site 6
S16
S
S
D
S
S
D
E
S
P
S
T
S
F
T
S
Site 7
S18
D
S
S
D
E
S
P
S
T
S
F
T
S
G
S
Site 8
T19
S
S
D
E
S
P
S
T
S
F
T
S
G
S
M
Site 9
S20
S
D
E
S
P
S
T
S
F
T
S
G
S
M
Y
Site 10
T22
E
S
P
S
T
S
F
T
S
G
S
M
Y
R
I
Site 11
S23
S
P
S
T
S
F
T
S
G
S
M
Y
R
I
K
Site 12
S25
S
T
S
F
T
S
G
S
M
Y
R
I
K
S
K
Site 13
Y27
S
F
T
S
G
S
M
Y
R
I
K
S
K
I
P
Site 14
S31
G
S
M
Y
R
I
K
S
K
I
P
N
E
H
K
Site 15
S50
V
F
R
K
D
L
I
S
A
M
K
L
P
D
S
Site 16
S57
S
A
M
K
L
P
D
S
H
H
I
N
P
D
S
Site 17
Y65
H
H
I
N
P
D
S
Y
Y
L
F
A
D
T
W
Site 18
Y66
H
I
N
P
D
S
Y
Y
L
F
A
D
T
W
K
Site 19
S85
K
G
V
Q
V
P
A
S
P
D
T
V
P
Q
P
Site 20
T88
Q
V
P
A
S
P
D
T
V
P
Q
P
S
L
R
Site 21
S93
P
D
T
V
P
Q
P
S
L
R
I
I
A
E
K
Site 22
Y112
L
F
I
R
P
R
K
Y
I
H
C
S
S
P
D
Site 23
S116
P
R
K
Y
I
H
C
S
S
P
D
T
T
E
P
Site 24
S117
R
K
Y
I
H
C
S
S
P
D
T
T
E
P
G
Site 25
T120
I
H
C
S
S
P
D
T
T
E
P
G
Y
I
N
Site 26
T121
H
C
S
S
P
D
T
T
E
P
G
Y
I
N
I
Site 27
Y125
P
D
T
T
E
P
G
Y
I
N
I
M
E
L
A
Site 28
T171
D
E
N
L
M
E
K
T
V
E
V
L
E
R
H
Site 29
Y197
E
E
G
L
G
I
E
Y
D
E
D
V
I
C
D
Site 30
S208
V
I
C
D
V
C
R
S
P
D
S
E
E
G
N
Site 31
S211
D
V
C
R
S
P
D
S
E
E
G
N
D
M
V
Site 32
T267
K
K
G
G
A
L
K
T
T
K
T
G
T
K
W
Site 33
T270
G
A
L
K
T
T
K
T
G
T
K
W
A
H
V
Site 34
T298
P
E
R
M
E
P
I
T
K
I
S
H
I
P
P
Site 35
T348
E
H
G
L
E
M
K
T
I
L
D
E
G
D
E
Site 36
S360
G
D
E
V
K
F
K
S
Y
C
L
K
H
S
Q
Site 37
S366
K
S
Y
C
L
K
H
S
Q
N
R
Q
K
L
G
Site 38
Y377
Q
K
L
G
E
A
E
Y
P
H
H
R
A
K
E
Site 39
S386
H
H
R
A
K
E
Q
S
Q
A
K
S
E
K
T
Site 40
S390
K
E
Q
S
Q
A
K
S
E
K
T
S
L
R
A
Site 41
S394
Q
A
K
S
E
K
T
S
L
R
A
Q
K
L
R
Site 42
Y408
R
E
L
E
E
E
F
Y
S
L
V
R
V
E
D
Site 43
S409
E
L
E
E
E
F
Y
S
L
V
R
V
E
D
V
Site 44
Y431
T
L
A
V
D
F
I
Y
N
Y
W
K
L
K
R
Site 45
Y433
A
V
D
F
I
Y
N
Y
W
K
L
K
R
K
S
Site 46
T467
P
K
E
E
S
I
H
T
R
M
R
M
F
M
H
Site 47
Y487
E
R
V
R
N
L
C
Y
M
I
S
R
R
E
K
Site 48
S490
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Site 49
S498
R
R
E
K
L
K
L
S
H
N
K
I
Q
E
Q
Site 50
S531
L
T
N
A
L
E
N
S
L
F
Y
P
P
P
R
Site 51
T540
F
Y
P
P
P
R
I
T
L
K
L
K
M
P
K
Site 52
S548
L
K
L
K
M
P
K
S
T
P
E
D
H
R
N
Site 53
T549
K
L
K
M
P
K
S
T
P
E
D
H
R
N
S
Site 54
S556
T
P
E
D
H
R
N
S
S
T
E
T
D
Q
Q
Site 55
S557
P
E
D
H
R
N
S
S
T
E
T
D
Q
Q
P
Site 56
T560
H
R
N
S
S
T
E
T
D
Q
Q
P
H
S
P
Site 57
S566
E
T
D
Q
Q
P
H
S
P
D
S
S
S
S
V
Site 58
S569
Q
Q
P
H
S
P
D
S
S
S
S
V
H
S
I
Site 59
S570
Q
P
H
S
P
D
S
S
S
S
V
H
S
I
R
Site 60
S571
P
H
S
P
D
S
S
S
S
V
H
S
I
R
N
Site 61
S572
H
S
P
D
S
S
S
S
V
H
S
I
R
N
M
Site 62
S575
D
S
S
S
S
V
H
S
I
R
N
M
Q
V
P
Site 63
S592
S
L
E
M
R
T
K
S
Y
P
R
Y
P
L
E
Site 64
Y593
L
E
M
R
T
K
S
Y
P
R
Y
P
L
E
S
Site 65
Y596
R
T
K
S
Y
P
R
Y
P
L
E
S
K
N
N
Site 66
S600
Y
P
R
Y
P
L
E
S
K
N
N
R
L
L
A
Site 67
S608
K
N
N
R
L
L
A
S
L
S
H
S
R
S
E
Site 68
S610
N
R
L
L
A
S
L
S
H
S
R
S
E
A
K
Site 69
S612
L
L
A
S
L
S
H
S
R
S
E
A
K
E
S
Site 70
S614
A
S
L
S
H
S
R
S
E
A
K
E
S
S
P
Site 71
S619
S
R
S
E
A
K
E
S
S
P
A
W
R
T
P
Site 72
S620
R
S
E
A
K
E
S
S
P
A
W
R
T
P
S
Site 73
T625
E
S
S
P
A
W
R
T
P
S
S
E
C
Y
H
Site 74
S627
S
P
A
W
R
T
P
S
S
E
C
Y
H
G
Q
Site 75
S628
P
A
W
R
T
P
S
S
E
C
Y
H
G
Q
S
Site 76
Y631
R
T
P
S
S
E
C
Y
H
G
Q
S
L
G
K
Site 77
S635
S
E
C
Y
H
G
Q
S
L
G
K
P
L
V
L
Site 78
S651
A
A
L
H
G
Q
S
S
I
G
N
G
K
S
Q
Site 79
S657
S
S
I
G
N
G
K
S
Q
P
N
S
K
F
A
Site 80
S661
N
G
K
S
Q
P
N
S
K
F
A
K
S
N
G
Site 81
S666
P
N
S
K
F
A
K
S
N
G
L
E
G
S
W
Site 82
S672
K
S
N
G
L
E
G
S
W
S
G
N
V
T
Q
Site 83
S674
N
G
L
E
G
S
W
S
G
N
V
T
Q
K
D
Site 84
T678
G
S
W
S
G
N
V
T
Q
K
D
S
S
S
E
Site 85
S682
G
N
V
T
Q
K
D
S
S
S
E
M
F
C
D
Site 86
S684
V
T
Q
K
D
S
S
S
E
M
F
C
D
Q
E
Site 87
S695
C
D
Q
E
P
V
F
S
P
H
L
V
S
Q
G
Site 88
S700
V
F
S
P
H
L
V
S
Q
G
S
F
R
K
S
Site 89
S703
P
H
L
V
S
Q
G
S
F
R
K
S
T
V
E
Site 90
S707
S
Q
G
S
F
R
K
S
T
V
E
H
F
S
R
Site 91
T708
Q
G
S
F
R
K
S
T
V
E
H
F
S
R
S
Site 92
S715
T
V
E
H
F
S
R
S
F
K
E
T
T
N
R
Site 93
T719
F
S
R
S
F
K
E
T
T
N
R
W
V
K
N
Site 94
T720
S
R
S
F
K
E
T
T
N
R
W
V
K
N
T
Site 95
Y733
N
T
E
D
L
Q
C
Y
V
K
P
T
K
N
M
Site 96
S741
V
K
P
T
K
N
M
S
P
K
E
Q
F
W
G
Site 97
S755
G
R
Q
V
L
R
R
S
A
G
R
A
P
Y
Q
Site 98
Y761
R
S
A
G
R
A
P
Y
Q
E
N
D
G
Y
C
Site 99
Y767
P
Y
Q
E
N
D
G
Y
C
P
D
L
E
L
S
Site 100
S774
Y
C
P
D
L
E
L
S
D
S
E
A
E
S
D
Site 101
S776
P
D
L
E
L
S
D
S
E
A
E
S
D
G
N
Site 102
S780
L
S
D
S
E
A
E
S
D
G
N
K
E
K
V
Site 103
S793
K
V
R
V
R
K
D
S
S
D
R
E
N
P
P
Site 104
S794
V
R
V
R
K
D
S
S
D
R
E
N
P
P
H
Site 105
S803
R
E
N
P
P
H
D
S
R
R
D
C
H
G
K
Site 106
S811
R
R
D
C
H
G
K
S
K
T
H
P
L
S
H
Site 107
T813
D
C
H
G
K
S
K
T
H
P
L
S
H
S
S
Site 108
S817
K
S
K
T
H
P
L
S
H
S
S
M
Q
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation